Journal of Preventive Medicine and Public Health

  • 제57권4호
  • /
  • Pages.307-318
  • /
  • 2024
  • /
  • 1975-8375(pISSN)
  • /
  • 2233-4521(eISSN)
대한예방의학회 (The Korean Society for Preventive Medicine)
권호 표지
DOI QR코드

DOI QR Code

Assessment of Epidemiological Data and Surveillance in Korea Substance Use Research: Insights and Future Directions

  • Meekang Sung (Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health) ;
  • Vaughan W. Rees (Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health) ;
  • Hannah Lee (MGH Institute for Technology Assessment, Harvard Medical School) ;
  • Mohammad S. Jalali (MGH Institute for Technology Assessment, Harvard Medical School)
  • 투고 : 2024.03.28
  • 심사 : 2024.05.29
  • 발행 : 2024.07.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives: Effective data collection and surveillance of epidemiological trends are essential in confronting the growing challenges associated with substance use (SU), especially in light of emerging trends and underreporting of cases. However, research and data are scarce regarding SU and substance use disorder (SUD) in Korea. Methods: We conducted a scoping review to identify data sources and surveillance methods used in SU research in Korea up to December 2023. This review was complemented by semi-structured consultations with experts in this area in Korea, whose feedback led to revisions of previously identified data sources and assessments. Results: Our review identified 32 publications conducting secondary analyses on existing data to examine the epidemiology of SU and SUD in Korea. Of these, 14 studies utilized clinical databases to explore the prescription patterns of addictive substances, particularly opioids. Eleven data sources showed promise for advancing SU research; however, they face substantial limitations, including a lack of available data, missing data, the absence of key variables, the exclusion of marginalized populations not captured within the clinical system, and complexities in matching individual-level data across time points and datasets. Conclusions: Current surveillance methods for SU in Korea face considerable challenges in accessibility, usability, and standardization. Moreover, existing data repositories may fail to capture information on populations not served by clinical or judicial systems. To systematically improve surveillance approaches, it is necessary to develop a robust and nationally representative survey, refine the use of existing clinical data, and ensure the availability of data on treatment facilities.

키워드

과제정보

We express our gratitude to Dr. Kyu-nam Heo from the Seoul National University College of Pharmacy, Dr. Haesun Suh from Kyung Hee University, and Dongeun Lee from the Pharmaceutical Association for a Healthy Society for their valuable insights and advice provided during this research.

참고문헌

  1. World Health Organization. International standards for the treatment of drug use disorders: revised edition incorporating results of field-testing; 2020 [cited 2024 May 1]. Available from: https://www.who.int/publications/i/item/international-standards-for-the-treatment-of-drug-use-disorders 
  2. Whiteford HA, Ferrari AJ, Degenhardt L, Feigin V, Vos T. The global burden of mental, neurological and substance use disorders: an analysis from the Global Burden of Disease Study 2010. PLoS One 2015;10(2):e0116820. https://doi.org/10.1371/journal.pone.0116820 
  3. GBD 2016 Alcohol and Drug Use Collaborators. The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Psychiatry 2018;5(12):987-1012. https://doi.org/10.1016/S2215-0366(18)30337-7 
  4. Prosecution Service. Narcotic crimes report [cited 2024 Jan 15]. Available from: https://www.spo.go.kr/site/spo/ex/board/List.do?cbIdx=1204 (Korean). 
  5. Lee HK, Lim HW, Chung HS, Chun YH, Cho SJ, Jiang OJ. The survey of drug users in Korea 2021 [cited 2024 Jan 15]. Available from: https://www.ncmh.go.kr/ncmh/board/common-View.do;jsessionid=LHOrQblrhkRvBjEY0Kj1G8vPQ1cGhNlgCAKCrA3av26YN9rqxfmWcMtVg26JPS1w.mohwwas1_servlet_engine1?no=4268&fno=84&bn=newsView&depart=&menu_cd=04_04_00_04&bno=&pageIndex=1&search_item=&search_content= (Korean). 
  6. Substance Abuse and Mental Health Services Administration (SAMHSA). National survey on drug use and health (NSDUH) [cited 2024 Jan 31]. Available from: https://www.samhsa.gov/data/data-we-collect/nsduh-national-survey-drug-use-and-health 
  7. Substance Abuse and Mental Health Services Administration (SAMHSA). Drug abuse warning network (DAWN-2011-DS0001); 2011[cited 2024 Jan 31]. Available from: https://www.datafiles.samhsa.gov/dataset/drug-abuse-warning-network-2011-dawn-2011-ds0001 
  8. Substance Abuse and Mental Health Services Administration (SAMHSA). Treatment episode data set: admissions 2021 (TEDS-A-2021-DS0001): client-level substance use data: admissions; 2021 [cited 2024 Jan 31]. Available from: https://www.datafiles.samhsa.gov/dataset/treatment-episode-data-set-admissions-2021-teds-2021-ds0001 
  9. Substance Abuse and Mental Health Services Administration (SAMHSA). National survey on drug use and health (NSDUH): population data (NSDUH-2022-DS0001); 2022 [cited 2024 Jan 31]. Available from: https://www.samhsa.gov/data/release/2022-national-survey-drug-use-and-health-nsduh-releases 
  10. Substance Abuse and Mental Health Services Administration (SAMHSA). 2022 National substance use and mental health services survey (N-SUMHSS) release; 2022 [cited 2024 Jan 31]. Available from: https://www.samhsa.gov/data/release/2022-national-substance-use-and-mental-health-services-survey-release 
  11. Substance Abuse and Mental Health Services Administration (SAMHSA). National survey of substance abuse treatment services (N-SSATS-2020-DS0001): 2020, data on substance abuse treatment facilities; 2021 [cited 2024 Jan 31]. Available from: https://www.samhsa.gov/data/report/national-survey-substance-abuse-treatment-services-n-ssats-2020-data-substance-abuse 
  12. Substance Abuse and Mental Health Services Administration (SAMHSA). Mental health client-level data 2021 (MH-CLD-2021-DS0001); 2021 [cited 2024 Jan 31]. https://www.datafiles.samhsa.gov/dataset/mental-health-client-level-data-2021-mh-cld-2021-ds0001
  13. Smart R, Kase CA, Taylor EA, Lumsden S, Smith SR, Stein BD. Strengths and weaknesses of existing data sources to support research to address the opioids crisis. Prev Med Rep 2019;17:101015. https://doi.org/10.1016/j.pmedr.2019.101015 
  14. Jalali MS, Ewing E, Bannister CB, Glos L, Eggers S, Lim TY, et al. Data needs in opioid systems modeling: challenges and future directions. Am J Prev Med 2021;60(2):e95-e105. https://doi.org/10.1016/j.amepre.2020.08.017 
  15. McAninch J, Secora A, Kornegay C, Staffa J. Pharmacoepidemiologic research on drugs of abuse. In: Strom BL, Kimmel SE, Hennessy S, editors. Pharmacoepidemiology. 6th ed. Hoboken: Wiley-Blackwell; 2019, p. 701-722. https://doi.org/10.1002/9781119413431.ch28 
  16. Arksey H, O'malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol 2005;8(1):19-32. https://doi.org/10.1080/1364557032000119616 
  17. Levac D, Colquhoun H, O'Brien KK. Scoping studies: advancing the methodology. Implement Sci 2010;5:69. https://doi.org/10.1186/1748-5908-5-69 
  18. Ko S, Sohn A. Behaviors and culture of drinking among Korean people. Iran J Public Health 2018;47(Suppl 1):47-56. 
  19. Gunter R, Szeto E, Jeong SH, Suh S, Waters AJ. Cigarette smoking in South Korea: a narrative review. Korean J Fam Med 2020;41(1):3-13. https://doi.org/10.4082/kjfm.18.0015 
  20. Lim KH, Nguyen NN, Qian Y, Williams JL, Lui DD, Bruera E, et al. Frequency, outcomes, and associated factors for opioid-induced neurotoxicity in patients with advanced cancer receiving opioids in inpatient palliative care. J Palliat Med 2018;21(12):1698-1704. https://doi.org/10.1089/jpm.2018.0169 
  21. Noh Y, Heo KN, Kim DA, Han JM, Lee JY, Ah YM. Risk factors for emergency department presentations after the initiation of opioid analgesics in non-cancer patients in Korea: a nationwide study. Medicina (Kaunas) 2023;59(3):519. https://doi.org/10.3390/medicina59030519 
  22. Noh Y, Heo KN, Yu YM, Lee JY, Ah YM. Trends in potentially inappropriate opioid prescribing and associated risk factors among Korean noncancer patients prescribed non-injectable opioid analgesics. Ther Adv Drug Saf 2022;13:20420986221091001. https://doi.org/10.1177/20420986221091001 
  23. Cho Y. A comparative psychiatric study on the narcotic addicts in Seoul, Korea. Folia Psychiatr Neurol Jpn 1972;26(2):107-131. https://doi.org/10.1111/j.1440-1819.1972.tb01117.x 
  24. Choi SK, Kim YH, Kim SM, Wie JH, Lee DG, Kwon JY, et al. Opioid analgesics are the leading cause of adverse drug reactions in the obstetric population in South Korea. Medicine (Baltimore) 2019;98(21):e15756. https://doi.org/10.1097/MD.0000000000015756 
  25. Kim JY, Kim JH, Yee J, Song SJ, Gwak HS. Risk factors of opioid-induced adverse reactions in elderly male outpatients of Korea Veterans Hospital. BMC Geriatr 2018;18(1):293. https://doi.org/10.1186/s12877-018-0990-1 
  26. Cho NR, Chang YJ, Lee D, Kim JR, Ko DS, Choi JJ. Trends in opioid prescribing practices in South Korea, 2009-2019: are we safe from an opioid epidemic? PLoS One 2021;16(5):e0250972. https://doi.org/10.1371/journal.pone.0250972 
  27. Heo KN, Lee JY, Ah YM. Development and validation of a risk-score model for opioid overdose using a national claims database. Sci Rep 2022;12(1):4974. https://doi.org/10.1038/s41598-022-09095-y 
  28. Kim J, Shin SJ, Yoon J, Kim HS, Lee JW, Kim YS, et al. Recent trends in opioid prescriptions in Korea from 2002 to 2015 based on the Korean NHIS-NSC cohort. Epidemiol Health 2022;44:e2022029. https://doi.org/10.4178/epih.e2022029 
  29. Oh TK, Song IA. Association between socioeconomic status and treatment in patients with low back or neck pain: a population-based cross-sectional study in South Korea. Reg Anesth Pain Med 2023;48(11):561-566. https://doi.org/10.1136/rapm-2022-104246 
  30. Yang BR, Oh IS, Li J, Jeon HL, Shin JY. Association between opioid analgesic plus benzodiazepine use and death: a case-crossover study. J Psychosom Res 2020;135:110153. https://doi.org/10.1016/j.jpsychores.2020.110153 
  31. Kim MJ, Kim JY, Lim YH, Hong SJ, Jeong JH, Choi HR, et al. Actual situation and prescribing patterns of opioids by pain physicians in South Korea. Korean J Pain 2022;35(4):475-487. https://doi.org/10.3344/kjp.2022.35.4.475 
  32. Kim CL, Hong SJ, Lim YH, Jeong JH, Moon HS, Choi HR, et al. Patients' perception about opioids and addiction in South Korea. Korean J Pain 2020;33(3):234-244. https://doi.org/10.3344/kjp.2020.33.3.234 
  33. Oh TK, Hwang I, Song IA. Long-term benzodiazepine usage and mortality in patients with chronic non-cancer musculoskeletal pain: a nationwide cohort study. Pain Pract 2024;24(3):409-418. https://doi.org/10.1111/papr.13312 
  34. Cho HY, Hwang Y, Shin S, Yoon S, Lee HJ. Propofol abuse among healthcare workers: an analysis of criminal cases using the database of the Supreme Court of South Korea's judgments. Korean J Anesthesiol 2022;75(5):391-396. https://doi.org/10.4097/kja.21507 
  35. Park HJ, Shin JY, Kim MH, Park BJ. Increased use in propofol and reported patterns of adverse events among anesthetics in Korea. Regul Toxicol Pharmacol 2015;71(3):478-483. https://doi.org/10.1016/j.yrtph.2015.02.001 
  36. Oh JY, Kang YR, An J, Choo E, Lee JH, Kwon HS, et al. Codeine prescription pattern and treatment responses in patients with chronic cough: a routinely collected institutional database analysis. J Thorac Dis 2023;15(4):2344-2354. https://doi.org/10.21037/jtd-22-1857 
  37. Kim SY, Kwon SM, Cho SN, Kwon DH, Kang BJ, Kim HT. A study on personality disorder of methamphetamine abuse or dependent patients in Korea. J Korean Soc Biol Ther Psychiatry 2003;9(2):204-212 (Korean). 
  38. Kim S, Suh HS. A population-based study on the risk of prescription opioid abuse in patients with chronic opioid use and cost-effectiveness of prescription drug monitoring program using a patient simulation model in South Korea. Int J Drug Policy 2023;112:103953. https://doi.org/10.1016/j.drugpo.2023.103953 
  39. Oh TK, Jeon YT, Choi JW. Trends in chronic opioid use and association with five-year survival in South Korea: a population-based cohort study. Br J Anaesth 2019;123(5):655-663. https://doi.org/10.1016/j.bja.2019.08.012 
  40. Song IA, Choi HR, Oh TK. Long-term opioid use and mortality in patients with chronic non-cancer pain: ten-year follow-up study in South Korea from 2010 through 2019. EClinicalMedicine 2022;51:101558. https://doi.org/10.1016/j.eclinm.2022.101558 
  41. Yoon D, Lee H, Baek YH, Jeong HE, Shin JY. Prevalence and its correlation with sustained opioid use in Korea: a group-based trajectory analysis. J Psychoactive Drugs 2021;53(3):224-229. https://doi.org/10.1080/02791072.2020.1856456 
  42. Lim D, Lee WK, Park H. Disability-adjusted life years (DALYs) for mental and substance use disorders in the Korean burden of disease study 2012. J Korean Med Sci 2016;31(Suppl 2):S191-S199. https://doi.org/10.3346/jkms.2016.31.S2.S191 
  43. Lee GY, Choi YJ. Analysis of Korean adolescents' sexual experience and substance use. Soc Behav Pers 2017;45(5):809-817. https://doi.org/10.2224/sbp.5935 
  44. Yang SJ, Stewart R, Lee JY, Kim JM, Kim SW, Shin IS, et al. Prevalence and correlates of problematic internet experiences and computer-using time: a two-year longitudinal study in Korean school children. Psychiatry Investig 2014;11(1):24-31. https://doi.org/10.4306/pi.2014.11.1.24 
  45. Sung S, Park SK, Min YH. Comparison of the factors associated with the habitual drug use among adolescents from multicultural and non-multicultural families in South Korea: analysis of data from the 14-15th (2018-2019) Korea Youth Risk Behavior Wed-based Survey. J Korean Soc Sch Health 2021;34(1):1-12 (Korean). https://doi.org/10.15434/kssh.2021.34.1.1 
  46. Yon H, Park S, Shin JU, Koyanagi A, Jacob L, Smith L, et al. Differences in pandemic-related factors associated with alcohol and substance use among Korean adolescents: nationwide representative study. Biomed Environ Sci 2023;36(6):542-548. https://doi.org/10.3967/bes2023.066 
  47. Kim R. Introduction to HIRA-NPS; 2012 [cited 2024 Jan 31]. Available from: https://repository.hira.or.kr/handle/2019.oak/894 (Korean). 
  48. Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol 2005;58(4):323-337. https://doi.org/10.1016/j.jclinepi.2004.10.012 
  49. National Health Insurance Service (NHIS). Introduction to the sample cohort DB [cited 2024 Jan 31]. Available from: https://nhiss.nhis.or.kr/bd/ab/bdaba002cv.do (Korean). 
  50. Kim SY, Cho NW, Yoo MS, Han SY, Oh JW. Narcotics information management system in South Korea: system development and innovation. BMC Health Serv Res 2023;23(1):73. https://doi.org/10.1186/s12913-023-09060-z 
  51. Yoon SH, Kim J, Yoon S, Lee HJ. Current status of opioid prescription in South Korea using narcotics information management system. Korean J Pain 2024;37(1):41-50. https://doi.org/10.3344/kjp.23234 
  52. Korean Association Against Drug Abuse (KAADA). 2022 Report on public awareness of misuse of drugs [cited 2024 Jan 31]. Available from: http://antidrug.drugfree.or.kr/page/?mIdx=100&mode=view&idx=16472&retUrl=mIdx%3D100 (Korean). 
  53. Korea Institute of Drug Safety & Risk Management. Korea adverse events reporting systems database (KAERS DB) [cited 2024 Jan 31]. Available from: https://open.drugsafe.or.kr/original/invitation.jsp (Korean). 
  54. Choi YJ, Kim MH, Chung EK, Lee JK, Yoon J, Yug JS, et al. Prevalence and seriousness of analgesic-induced adverse events in Korea: a 10-year nationwide surveillance. J Patient Saf 2020;16(4):e215-e224. https://doi.org/10.1097/PTS.0000000000000742 
  55. Kim Y, Choi S, Chun C, Park S, Khang YH, Oh K. Data resource profile: the Korea Youth Risk Behavior Web-based Survey (KYRBS). Int J Epidemiol 2016;45(4):1076-1076e. https://doi.org/10.1093/ije/dyw070 
  56. Korea Disease Control and Prevention Agency. Discharge injury survey [cited 2024 Jan 15]. Available from: https://www.kdca.go.kr/injury/biz/injury/bsnsIntrcn/lhstlDamgDepthsExaminMain.do (Korean). 
  57. Korea Disease Control and Prevention Agency. Emergency room injury survey [cited 2024 Jan 15]. Available from: https://www.kdca.go.kr/injury/biz/injury/bsnsIntrcn/emrrscDamgPatntDepthsExaminMain.do (Korean). 
  58. Statistics Korea. Research and planning division of mental health research institute South Korea mental health survey 2022 [cited 2024 Jan 15]. Available from: https://kostat.go.kr/board.es?mid=a10409070000&bid=12030&tag=&act=view&list_no=422670&ref_bid= (Korean). 
  59. Korean Statistical Information Service. Cause of death survey [cited 2024 Jan 15]. Available from: https://kosis.kr/statHtml/statHtml.do?orgId=101&tblId=DT_1B34E07&conn_path=I2 (Korean). 
  60. Hong JP. Mental health survey 2016 [cited 2024 Jan 15]. Available from: https://www.mohw.go.kr/synap/doc.html?fn=1493191278238_20170426162121.pdf&rs=/upload/result/202407/ (Korean). 
  61. Kim SW. Narcotic substances addiction survey 2014 [cited 2024 Feb 9]. Available from: https://shprc.dongguk.edu/cmmn/fileDown.do?filename=2014+%EB%A7%88%EC%95%BD%EB%A5%98+%EC%A4%91%EB%8F%85%EC%9E%90+%EC%8B%A4%ED%83%9C%EC%A1%B0%EC%82%AC.pdf&filepath=/shprc/files/article/project/185638/&filerealname=7AAA3369F6EE4A90BA0EC2F1EA06C486.pdf (Korean). 
  62. Kim D, Cho K, Chae SH, Choi MM, Oh SY, Lee KM, et al. A fact-finding survey on the people addicted to drugs in year 2009; 2010 [cited 2024 Feb 9]. Available from: https://www.mohw.go.kr/boardDownload.es?bid=0046&list_no=357647&seq=1 (Korean). 
  63. Seong SC, Kim YY, Khang YH, Park JH, Kang HJ, Lee H, et al. Data resource profile: the National Health Information Database of the National Health Insurance Service in South Korea. Int J Epidemiol 2017;46(3):799-800. https://doi.org/10.1093/ije/dyw253 
  64. Substance Abuse and Mental Health Services Administration (SAMHSA). 2022 NSDUH detailed tables; 2023 [cited 2024 Jan 15]. Available from: https://www.samhsa.gov/data/report/2022-nsduh-detailed-tables 
  65. Wang J, Doogan N, Thompson K, Bernson D, Feaster D, Villani J, et al. Massachusetts prevalence of opioid use disorder estimation revisited: comparing a Bayesian approach to standard capture-recapture methods. Epidemiology 2023;34(6):841-849. https://doi.org/10.1097/EDE.0000000000001653 
  66. 7th Narcotics Countermeasures Council. Comprehensive measures for narcotics control. Office for government policy coordination [cited 2024 Apr 29]. Available from: https://www.korea.kr/briefing/policyBriefingView.do?newsId=156601098#policyBriefing (Korean). 
  67. Azofeifa A, Stroup DF, Lyerla R, Largo T, Gabella BA, Smith CK, et al. Evaluating behavioral health surveillance systems. Prev Chronic Dis 2018;15:E53. https://doi.org/10.5888/pcd15.170459 
  68. Groseclose SL, Buckeridge DL. Public health surveillance systems: recent advances in their use and evaluation. Annu Rev Public Health 2017;38:57-79. https://doi.org/10.1146/annurevpublhealth-031816-044348 
  69. Trevethan R. Sensitivity, specificity, and predictive values: foundations, pliabilities, and pitfalls in research and practice. Front Public Health 2017;5:307. https://doi.org/10.3389/fpubh.2017.00307