DOI QR코드

DOI QR Code

A study on the positioning of fine scintillation pixels in a positron emission tomography detector through deep learning of simulation data

  • Byungdu Jo (Department of Radiological Science, Dongseo University) ;
  • Seung-Jae Lee (Department of Radiological Science, Dongseo University)
  • 투고 : 2023.11.15
  • 심사 : 2023.12.11
  • 발행 : 2024.05.25

초록

In order to specify the location of the scintillation pixel that interacted with gamma rays in the positron emission tomography (PET) detector, conventionally, after acquiring a flood image, the location of interaction between the scintillation pixel and gamma ray could be specified through a pixel-segmentation process. In this study, the experimentally acquired signal was specified as the location of the scintillation pixel directly, without any conversion process, through the simulation data and the deep learning algorithm. To evaluate the accuracy of the specification of the scintillation pixel location through deep learning, a comparative analysis with experimental data through pixel segmentation was performed. In the same way as in the experiment, a detector was configured on the simulation, a model was built using the acquired data through deep learning, and the location was specified by applying the experimental data to the built model. Accuracy was calculated through comparative analysis between the specified location and the location obtained through the segmentation process. As a result, it showed excellent accuracy of about 85 %. When this method is applied to a PET detector, the position of the scintillation pixel of the detector can be specified simply and conveniently, without additional work.

키워드

과제정보

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (No. 2022R1I1A3064473).

참고문헌

  1. M.U. Ghani, W.C. Karl, Fast enhanced CT metal artifact reduction using data domain deep learning, IEEE Trans. Comput. Imag. 6 (2020) 181-193.  https://doi.org/10.1109/TCI.2019.2937221
  2. K. Zhang, W. Zuo, Y. Chen, D. Meng, L. Zhang, Beyond a Gaussian denoiser: residual learning of deep CNN for image denoising, IEEE Trans. Image Process. 26 (2017) 3142-3155.  https://doi.org/10.1109/TIP.2017.2662206
  3. M.F. Spadea, M. Maspero, P. Zaffino, J. Seco, Deep learning based synthetic-CT generation in radiotherapy and PET: a review, Med. Phys. 48 (2021) 6537-6566.  https://doi.org/10.1002/mp.15150
  4. M.H. Hesamian, W. Jia, X. He, P. Kennedy, Deep learning techniques for medical image segmentation: achievements and challenges, J. Digit. Imag. 32 (2019) 582-596.  https://doi.org/10.1007/s10278-019-00227-x
  5. J. Solomon, P. Lyu, D. Marin, E. Samei, Noise and spatial resolution properties of a commercially available deep learning-based CT reconstruction algorithm, Med. Phys. 47 (2020) 3961-3971.  https://doi.org/10.1002/mp.14319
  6. A.S. Chaudhari, E. Mittra, G.A. Davidzon, P. Gulaka, H. Gandhi, A. Brown, T. Zhang, S. Srinivas, E. Gong, G. Zaharchuk, H. Jadvar, NpJ Digit. Med. 23 (2021) 127. 
  7. G. Jaliparthi, P.F. Martone, A.V. Stolin, R.R. Raylman, Deep residual-convolutional neural networks for event positioning in an monolithic annular PET scanner, Phys. Med. Biol. 66 (2021), 145008. 
  8. H. Arabi, A. AkhavanAllaf, A. Sanaat, I. Shiri, H. Zaidi, The promise of artificial intelligence and deep learning in PET and SPECT imaging, Phys. Med. 83 (2021) 122-137.  https://doi.org/10.1016/j.ejmp.2021.03.008
  9. T. Wang, Y. Lei, Y. Fu, W.J. Curran, T. Liu, J.A. Nye, X. Yang, Machine learning in quantitative PET: a review of attenuation correction and low-count image reconstruction methods, Phys. Med. 76 (2020) 294-306.  https://doi.org/10.1016/j.ejmp.2020.07.028
  10. S.-J. Lee, C.-H. Baek, A new method for position determination of scintillation pixel in PET detector module using simulation LUT and MLPE, Nucl. Instrum. Methods Phys. Res. 1016 (2021), 165750. 
  11. B. Jo, S.-J. Lee, Preliminary study on PET detector digital positioning of scintillation pixels using deep learning, J. Kor. Phys. Soc. 83 (2023) 403-408.
  12. F. Cayouette, D. Laurendeau, C. Moisan, DETECT2000: an improved monte-carlo simulator for the computer aided design of photon sensing devices, Proc. SPIE, Quebec 4833 (2003) 69-76. 
  13. M. Makek, D. Bosnar, A.M. Kozuljevic, L. Pavelic, Investigation of GaGG:Ce with TOFPET2 ASIC readout for applications in gamma imaging systems, Crystals 10 (2020) 1073. 
  14. J. Du, J.P. Schmall, Y. Yang, K. Di, E. Roncali, G.S. Mitchell, S. Buckley, C. Jackson, S.R. Cherry, Med. Phys. 42 (2015) 585-599. https://doi.org/10.1118/1.4905088