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Advanced Bronchoscopic Diagnostic Techniques in Lung Cancer

  • Dongil Park (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Chungnam National University College of Medicine)
  • 투고 : 2023.10.06
  • 심사 : 2024.02.22
  • 발행 : 2024.07.31

초록

The increasing incidence of incidental pulmonary nodules necessitates effective biopsy techniques for accurate diagnosis and treatment planning. This paper reviews the widely used advanced bronchoscopic techniques, such as radial endobronchial ultrasound-guided transbronchial lung biopsy, electromagnetic navigation bronchoscopy, and the cutting-edge robotic-assisted bronchoscopy. In addition, the cryobiopsy technique, which can enhance diagnostic yield by combination with conventional biopsy tools, is described for application to peripheral pulmonary lesions and mediastinal lesions, respectively.

키워드

과제정보

This work was supported by the National Research Foundation of Korea (NRF) grant, funded by the Korean Government (MSIT) (No. 2022R1A2C2010148).

참고문헌

  1. National Institutes of Health, National Cancer Institute. Cancer stat facts: lung and bronchus cancer [Internet]. Bethesda: NIH; 2023 [cited 2024 Mar 25]. Available from: https://seer.cancer.gov/statfacts/html/lungb.html.
  2. National Lung Screening Trial Research Team; Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011;365:395-409.
  3. de Koning HJ, van der Aalst CM, de Jong PA, Scholten ET, Nackaerts K, Heuvelmans MA, et al. Reduced lung-cancer mortality with volume CT screening in a randomized trial. N Engl J Med 2020;382:503-13.
  4. US Preventive Services Task Force; Krist AH, Davidson KW, Mangione CM, Barry MJ, Cabana M, et al. Screening for lung cancer: US Preventive Services Task Force Recommendation Statement. JAMA 2021;325:962-70.
  5. Okereke IC, Nishi S, Zhou J, Goodwin JS. Trends in lung cancer screening in the United States, 2016-2017. J Thorac Dis 2019;11:873-81.
  6. Schmid-Bindert G, Vogel-Claussen J, Gutz S, Fink J, Hoffmann H, Eichhorn ME, et al. Incidental pulmonary nodules: what do we know in 2022. Respiration 2022;101:1024-34.
  7. National Comprehensive Cancer Network. Non-small cell lung cancer (version 3.2023) [Internet]. Plymouth Meeting: NCCN; 2023 [cited 2024 Mar 25]. Available from: https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf.
  8. Ho AT, Gorthi R, Lee R, Chawla M, Patolia S. Solitary lung nodule: CT-guided transthoracic biopsy vs transbronchial biopsy with endobronchial ultrasound and flexible bronchoscope, a meta-analysis of randomized controlled trials. Lung 2023;201:85-93.
  9. Yu Lee-Mateus A, Reisenauer J, Garcia-Saucedo JC, Abia-Trujillo D, Buckarma EH, Edell ES, et al. Robotic-assisted bronchoscopy versus CT-guided transthoracic biopsy for diagnosis of pulmonary nodules. Respirology 2023;28:66-73.
  10. Kim SH, Mok J, Jo EJ, Kim MH, Lee K, Kim KU, et al. The additive impact of transbronchial cryobiopsy using a 1.1-mm diameter cryoprobe on conventional biopsy for peripheral lung nodules. Cancer Res Treat 2023;55:506-12.
  11. Matsumoto Y, Nakai T, Tanaka M, Imabayashi T, Tsuchida T, Ohe Y. Diagnostic outcomes and safety of cryobiopsy added to conventional sampling methods: an observational study. Chest 2021;160:1890-901.
  12. Chung C, Kim Y, Lee JE, Kang DH, Park D. Diagnostic value of transbronchial lung cryobiopsy using an ultrathin cryoprobe and guide sheath for peripheral pulmonary lesions. J Bronchology Interv Pulmonol 2024;31:13-22.
  13. Chen A, Chenna P, Loiselle A, Massoni J, Mayse M, Misselhorn D. Radial probe endobronchial ultrasound for peripheral pulmonary lesions: a 5-year institutional experience. Ann Am Thorac Soc 2014;11:578-82.
  14. Wang Memoli JS, Nietert PJ, Silvestri GA. Meta-analysis of guided bronchoscopy for the evaluation of the pulmonary nodule. Chest 2012;142:385-93.
  15. Sainz Zuniga PV, Vakil E, Molina S, Bassett RL Jr, Ost DE. Sensitivity of radial endobronchial ultrasound-guided bronchoscopy for lung cancer in patients with peripheral pulmonary lesions: an updated meta-analysis. Chest 2020;157:994-1011.
  16. Mehta RM, Biraris P, Aurangabadwalla R, Kalpakam H, Bhat R, Bajaj P. Use of an extended working channel in high-risk transbronchial biopsy: an innovative use of an existing modality to minimize bleeding and hypoxia. Innovations (Phila) 2021;16:75-9.
  17. Huang CT, Chang LY, Chen CY, Ruan SY, Lin CK, Tsai YJ, et al. Endobronchial ultrasound-guided transbronchial biopsy with or without a guide sheath for peripheral pulmonary malignancy. ERJ Open Res 2021;7:00267-2021.
  18. Oki M, Saka H, Imabayashi T, Himeji D, Nishii Y, Nakashima H, et al. Guide sheath versus non-guide sheath method for endobronchial ultrasound-guided biopsy of peripheral pulmonary lesions: a multicentre randomised trial. Eur Respir J 2022;59:2101678.
  19. Park S, Yoon HY, Han Y, Wang KS, Park SY, Ryu YJ, et al. Diagnostic yield of additional conventional transbronchial lung biopsy following radial endobronchial ultrasound lung biopsy for peripheral pulmonary lesions. Thorac Cancer 2020;11:1639-46.
  20. Kunimasa K, Tachihara M, Tamura D, Tokunaga S, Nakata K, Hazeki N, et al. Diagnostic utility of additional conventional techniques after endobronchial ultrasonography guidance during transbronchial biopsy. Respirology 2016;21:1100-5.
  21. Oki M, Saka H. Diagnostic value of ultrathin bronchoscopy in peripheral pulmonary lesions: a narrative review. J Thorac Dis 2020;12:7675-82.
  22. Oki M, Saka H, Himeji D, Imabayashi T, Nishii Y, Ando M. Value of adding ultrathin bronchoscopy to thin bronchoscopy for peripheral pulmonary lesions: a multicentre prospective study. Respirology 2023;28:152-8.
  23. Pickering EM, Kalchiem-Dekel O, Sachdeva A. Electromagnetic navigation bronchoscopy: a comprehensive review. AME Med J 2018;3:117.
  24. Patrucco F, Gavelli F, Daverio M, Antonini C, Boldorini R, Casadio C, et al. Electromagnetic navigation bronchoscopy: where are we now?: five years of a single-center experience. Lung 2018;196:721-7.
  25. Seijo LM, de Torres JP, Lozano MD, Bastarrika G, Alcaide AB, Lacunza MM, et al. Diagnostic yield of electromagnetic navigation bronchoscopy is highly dependent on the presence of a bronchus sign on CT imaging: results from a prospective study. Chest 2010;138:1316-21.
  26. Yutaka Y, Sato T, Isowa M, Murata Y, Tanaka S, Yamada Y, et al. Electromagnetic navigation bronchoscopy versus virtual bronchoscopy navigation for improving the diagnosis of peripheral lung lesions: analysis of the predictors of successful diagnosis. Surg Today 2022;52:923-30.
  27. Folch EE, Pritchett MA, Nead MA, Bowling MR, Murgu SD, Krimsky WS, et al. Electromagnetic navigation bronchoscopy for peripheral pulmonary lesions: one-year results of the prospective, multicenter NAVIGATE study. J Thorac Oncol 2019;14:445-58.
  28. Ali MS, Sethi J, Taneja A, Musani A, Maldonado F. Computed tomography bronchus sign and the diagnostic yield of guided bronchoscopy for peripheral pulmonary lesions: a systematic review and meta-analysis. Ann Am Thorac Soc 2018;15:978-87.
  29. Folch EE, Bowling MR, Pritchett MA, Murgu SD, Nead MA, Flandes J, et al. NAVIGATE 24-month results: electromagnetic navigation bronchoscopy for pulmonary lesions at 37 centers in Europe and the United States. J Thorac Oncol 2022;17:519-31.
  30. Folch EE, Labarca G, Ospina-Delgado D, Kheir F, Majid A, Khandhar SJ, et al. Sensitivity and safety of electromagnetic navigation bronchoscopy for lung cancer diagnosis: systematic review and meta-analysis. Chest 2020; 158:1753-69.
  31. Chaddha U, Kovacs SP, Manley C, Hogarth DK, Cumbo-Nacheli G, Bhavani SV, et al. Robot-assisted bronchoscopy for pulmonary lesion diagnosis: results from the initial multicenter experience. BMC Pulm Med 2019;19:243.
  32. Kalchiem-Dekel O, Connolly JG, Lin IH, Husta BC, Adusumilli PS, Beattie JA, et al. Shape-sensing robotic-assisted bronchoscopy in the diagnosis of pulmonary parenchymal lesions. Chest 2022;161:572-82.
  33. Styrvoky K, Schwalk A, Pham D, Chiu HT, Rudkovskaia A, Madsen K, et al. Shape-sensing robotic-assisted bronchoscopy with concurrent use of radial endobronchial ultrasound and cone beam computed tomography in the evaluation of pulmonary lesions. Lung 2022;200:755-61.
  34. ClinicalTrials.gov. Clinical utility for ion endoluminal system (ClinicalTrials.gov Identifier: NCT03893539) [Internet]. Bethesda: NIH; 2022 [cited 2024 Mar 25]. Available from: https://classic.clinicaltrials.gov/ct2/show/NCT03893539.
  35. Ost D, Pritchett M, Reisenauer J, Simoff M, Diaz-Mendoza J, Fernandez-Bussy S, et al. Prospective multicenter analysis of shape-sensing robotic-assisted bronchoscopy for the biopsy of pulmonary nodules: results from the PRECIsE study. Chest 2021;160:A2531-3.
  36. Wikipedia. Joule-Thomson effect [Internet]. San Francisco: Wikimedia; 2024 [cited 2024 Mar 25]. Available from: https://en.wikipedia.org/wiki/Joule%E2%80%93Thomson_effect.
  37. Korevaar DA, Colella S, Fally M, Camuset J, Colby TV, Hagmeyer L, et al. European Respiratory Society guidelines on transbronchial lung cryobiopsy in the diagnosis of interstitial lung diseases. Eur Respir J 2022;60:2200425.
  38. Wang S, Feng Y, Zhang Y, Tian Y, Gu S, Wu X, et al. Transbronchial lung biopsy versus transbronchial lung cryobiopsy in critically ill patients with undiagnosed acute hypoxemic respiratory failure: a comparative study. BMC Pulm Med 2022;22:177.
  39. Oberg CL, Lau RP, Folch EE, He T, Ronaghi R, Susanto I, et al. Novel robotic-assisted cryobiopsy for peripheral pulmonary lesions. Lung 2022;200:737-45.
  40. Benn BS, Gmehlin CG, Kurman JS, Doan J. Does transbronchial lung cryobiopsy improve diagnostic yield of digital tomosynthesis-assisted electromagnetic navigation guided bronchoscopic biopsy of pulmonary nodules?: a pilot study. Respir Med 2022;202:106966.
  41. Herath S. Using cryobiopsy with radial EBUS in highbleeding-risk, peripheral pulmonary lesions (PPL): description of cases and technique. Respirol Case Rep 2023;11:e01125.
  42. Nakai T, Watanabe T, Kaimi Y, Ogawa K, Matsumoto Y, Sawa K, et al. Safety profile and risk factors for bleeding in transbronchial cryobiopsy using a two-scope technique for peripheral pulmonary lesions. BMC Pulm Med 2022;22:20.
  43. Herth FJ, Ernst A, Eberhardt R, Vilmann P, Dienemann H, Krasnik M. Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically normal mediastinum. Eur Respir J 2006;28:910-4.
  44. Liu YL, Liu XR, Li H, Chen FJ, Liao H, Xie CM. Efficiency of EBUS-TBNA for diagnosing benign and malignant lymphadenopathy. J Acute Dis 2018;7:197-201.
  45. Fan Y, Zhang AM, Wu XL, Huang ZS, Kontogianni K, Sun K, et al. Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial. Lancet Respir Med 2023;11:256-64.
  46. Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, et al. Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial. Eur Respir J 2021;58:2100055.
  47. Agrawal A, Ghori U, Chaddha U, Murgu S. Combined EBUS-IFB and EBUS-TBNA vs EBUS-TBNA alone for intrathoracic adenopathy: a meta-analysis. Ann Thorac Surg 2022;114:340-8.
  48. Dooms C, Vander Borght S, Yserbyt J, Testelmans D, Wauters E, Nackaerts K, et al. A randomized clinical trial of Flex 19G needles versus 22G needles for endobronchial ultrasonography in suspected lung cancer. Respiration 2018;96:275-82.
  49. Kinoshita T, Ujiie H, Schwock J, Fujino K, McDonald C, Lee CY, et al. Clinical evaluation of the utility of a flexible 19-gauge EBUS-TBNA needle. J Thorac Dis 2018;10:2388-96.