Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Imaging guided adrenalectomy with Indocyanine green fluorescence in a dog with a pheochromocytoma

  • Seung-yeon Yu (Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University) ;
  • Sungin Lee (Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University)
  • Received : 2024.05.15
  • Accepted : 2024.06.25
  • Published : 2024.07.31
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Abstract

Importance: This case report presents the successful surgical removal of a pheochromocytoma in a dog using indocyanine green (ICG) fluorescence imaging. Case Presentation: A 10-year-old, 6.87 kg, spayed female poodle was referred for an abdominal mass and eight episodes of vomiting. Computed tomography revealed masses in the spleen and left adrenal gland. Based on the plasma normetanephrine levels, the patient was diagnosed with pheochromocytoma. Subsequently, a total splenectomy and left adrenalectomy were performed. A dose of 5 mg/kg ICG was administered intravenously 24 h prior to surgery. Using ICG allowed visualization of tumor margins, aiding in complete resection and minimizing anesthesia-related risks. Conclusions and Relevance: No evidence of recurrence or metastasis has been observed for 12 months. To our knowledge, this is the first report of the surgical removal of a pheochromocytoma using intraoperative ICG imaging in veterinary medicine. This case highlights the efficacy of ICG fluorescence imaging as a valuable tool for the surgical management of adrenal tumors in veterinary medicine.

Keywords

Acknowledgement

This research was supported by "Regional Innovation Strategy (RIS)" through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (MOE) (2024RIS-001), and also supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (RS-2023-00253736).

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