International Journal of Stem Cells

Korean Society for Stem Cell Research (한국줄기세포학회)
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Guidelines for Packaging, Transport, and Storage of Source Cells for Organoids

  • Sungin Lee (Institute of Quantum Biophysics, Sungkyunkwan University) ;
  • Dayeon Kwon (Institute of Quantum Biophysics, Sungkyunkwan University) ;
  • Han Byeol Lee (Institute of Quantum Biophysics, Sungkyunkwan University) ;
  • Sooyeon Jeon (Institute of Quantum Biophysics, Sungkyunkwan University) ;
  • Chihye Park (Institute of Quantum Biophysics, Sungkyunkwan University) ;
  • Tae Sung Kim (Division of Toxicological Research, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety) ;
  • Jin Hee Lee (Division of Toxicological Research, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety) ;
  • Il Ung Oh (Division of Toxicological Research, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety) ;
  • Sun-Ju Ahn (Institute of Quantum Biophysics, Sungkyunkwan University)
  • Received : 2024.04.08
  • Accepted : 2024.04.24
  • Published : 2024.05.30
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Abstract

This report presents guidelines for the systematic management of packaging, storage, transportation, and traceability of source cells used for organoid research. Given the important role of source cells in organoid studies, it is important to ensure the preservation of their quality and integrity throughout transportation and distribution processes. The proposed guidelines, therefore, call for a cohesive strategy through these stages to minimize the risks of contamination, deterioration, and loss-threats that significantly compromise the safety, efficacy, and efficiency of source cells. Central to these guidelines is the quality control measures that include roles and responsibilities across the entire supply chain, with recommendations specific to packaging materials, transportation facilities, and storage management. Furthermore, the need for an integrated management system is emphasized, spanning from source cell collection to the final application. This system is crucial for maintaining the traceability and accountability of source cells, facilitating the sharing, distribution, and utilization on a global scale, and supporting to advance organoid research and development.

Keywords

Acknowledgement

We thank those who contributed to the successful completion of this manuscript. We would like to thank first the Ministry of Food and Drug Safety, OSI committee chairs and members, and the Institute of Quantum Biophysics, especially, Professor Luke Lee for his invaluable insights.

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