Journal of Food Hygiene and Safety (한국식품위생안전성학회지)

The Korean Society of Food Hygiene and Safety (한국식품위생안전성학회)
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Microcystins and Nodularin in Agricultural Products: Toxicity, Analytical Methods, Contamination Pathway, Occurrence, and Safety Management

농산물 내 마이크로시스틴과 노둘라린: 독성, 분석법, 오염 경로, 오염 현황 및 관리 동향

  • Su Been Park (School of Food Science and Technology, Chung-Ang University) ;
  • Sang Yoo Lee (School of Food Science and Technology, Chung-Ang University) ;
  • Ji Eun Park (School of Food Science and Technology, Chung-Ang University) ;
  • Jae Sung Kim (KOTITI Testing & Research Institute) ;
  • Hyang Sook Chun (School of Food Science and Technology, Chung-Ang University)
  • 박수빈 (중앙대학교 생명공학대학 식품공학과) ;
  • 이상유 (중앙대학교 생명공학대학 식품공학과) ;
  • 박지은 (중앙대학교 생명공학대학 식품공학과) ;
  • 김재성 ((사)코티티시험연구원) ;
  • 전향숙 (중앙대학교 생명공학대학 식품공학과)
  • Received : 2024.04.02
  • Accepted : 2024.04.25
  • Published : 2024.06.30
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Abstract

The peptide-type hepatotoxins microcystins (MCs) and nodularin (NOD) are secondary metabolites produced by cyanobacteria. MCs and NOD can bioaccumulate in agricultural products through toxin-contaminated water, soil, and manure and can cause human health risks through the consumption of agricultural products. As interest in the contamination of agricultural products by MCs or NOD has recently emerged, occurrence studies based on various analysis methods for agricultural products have been conducted. However, studies on agricultural products are still insufficient compared to research on drinking water and seafood. In addition, research is primarily conducted on agricultural products grown in areas where green algae occur, but not on marketed products. In the present study, we review the physicochemical properties, toxicity, analysis methods, occurrence studies, and management status of MCs and NOD in agricultural products to build a foundation for systematic monitoring and safety management.

펩타이드형 독소인 마이크로시스틴(microcystins, MCs)과 노둘라린(nodularin, NOD)은 남조류라고도 알려진 시아노박테리아에 의해 생성되는 2차 대사산물로, 독소에 오염된 물, 토양 및 비료를 사용함으로써 농산물 내에 축적되고 이를 사람이 섭취함으로써 건강상 위해가 발생할 수 있다. 최근 MCs과 NOD의 농산물 내 오염에 대한 관심이 대두되며 국내외에서 여러 분석법을 기반으로 농산물 내 오염 수준을 조사하고 있다. 하지만 아직까지 수행된 연구가 많지 않으며, 특히 펩타이드형 독소 중 MCs의 분석 연구에 치중되어 있거나 오염 취약 지역에서 재배한 농산물이 주로 오염도 조사에 사용되는 등 연구에 한계가 있으므로 MCs과 NOD의 관리를 위해서는 보다 많은 체계적인 연구가 필요할 것으로 생각된다. 본 연구에서는 체계적인 모니터링 및 안전관리의 기반을 마련하기 위해 MCs 및 NOD의 이화학적 특성, 독성, 분석법, 오염사례 및 관리현황에 대해 기술하였다.

Keywords

Acknowledgement

본 연구는 2024년도 식품의약품안전처의 연구개발비(24192MFDS303, 21153MFDS605)로 수행되었으며, 이에 감사드립니다.

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