Annals of Laboratory Medicine

Korean Society for Laboratory Medicine (대한진단검사의학회)
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The LEAP Checklist for Laboratory Evaluation and Analytical Performance Characteristics Reporting of Clinical Measurement Procedures

  • Tze Ping Loh (Department of Laboratory Medicine, National University Hospital) ;
  • Brian R Cooke (Department of Clinical Biochemistry, PathWest Laboratory Medicine, Fiona Stanley Hospital) ;
  • Thi Chi Mai Tran (Faculty of Medical Technology, Hanoi Medical University) ;
  • Corey Markus (Flinders University International Centre for Point-of-Care Testing, Flinders Health and Medical Research Institute) ;
  • Rosita Zakaria (Department of Laboratory Medicine, School of Health and Biomedical Sciences, RMIT University) ;
  • Chung Shun Ho (Biomedical Mass Spectrometry Unit, Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong) ;
  • Elvar Theodorsson (Division of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Linkoping University) ;
  • Ronda F Greaves (Victorian Clinical Genetics Services, Murdoch Children's Research Institute) ;
  • IFCC Working Group on Method Evaluation Protocols (WG-MEP) (IFCC Working Group on Method Evaluation Protocols (WG-MEP))
  • Received : 2023.08.31
  • Accepted : 2023.09.07
  • Published : 2024.03.01
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Abstract

Reporting a measurement procedure and its analytical performance following method evaluation in a peer-reviewed journal is an important means for clinical laboratory practitioners to share their findings. It also represents an important source of evidence base to help others make informed decisions about their practice. At present, there are significant variations in the information reported in laboratory medicine journal publications describing the analytical performance of measurement procedures. These variations also challenge authors, readers, reviewers, and editors in deciding the quality of a submitted manuscript. The International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Method Evaluation Protocols (IFCC WG-MEP) developed a checklist and recommends its adoption to enable a consistent approach to reporting method evaluation and analytical performance characteristics of measurement procedures in laboratory medicine journals. It is envisioned that the Laboratory Evaluation and Analytical Performance Characteristics (LEAP) checklist will improve the standardisation of journal publications describing method evaluation and analytical performance characteristics, improving the quality of the evidence base that is relied upon by practitioners.

Keywords

Acknowledgement

We wish to acknowledge the helpful comments provided by the corresponding members of the IFCC WG-MEP that have been incorporated into the published version of the checklist.

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