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Lysolecithins improved growth performance, nutrient digestibility, immunity, and antioxidant ability in broiler chickens

  • Yuanli Cai (College of Life Science, Qilu Normal University) ;
  • Lu Gao (Key Laboratory of Efficient Utilization of Non-grain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University) ;
  • Bochen Song (Key Laboratory of Efficient Utilization of Non-grain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University) ;
  • Zhigang Song (Key Laboratory of Efficient Utilization of Non-grain Feed Resources, College of Animal Science and Technology, Shandong Agricultural University)
  • 투고 : 2023.10.24
  • 심사 : 2023.12.27
  • 발행 : 2024.08.01

초록

Objective: This study investigated the effects of dietary supplementation with lysolecithins (LPC) on growth performance, nutrient digestibility, blood profiles, immunity, and liver health in broiler chickens. Methods: A cohort of 240 one-day-old male Arbor Acres broilers of comparable weight was divided into four treatment groups, each comprising six replicates of 10 birds. The groups were defined as follows: positive control with recommended metabolizable energy (PC+ME), negative control with 90 kcal/kg reduced ME (NC+ME), PC supplemented with 300 mg/kg LPC (PC+LPC), and NC supplemented with 300 mg/kg LPC (NC+LPC). Results: LPC supplementation led to a statistically significant reduction in the feed conversion ratio (p = 0.05) and a decrease in the proportion of abdominal fat and the liver (p<0.05). Digestibility of dry matter was also enhanced (p<0.05). Malondialdehyde concentrations in the liver were significantly reduced by LPC (p<0.01), with a noteworthy interaction between energy levels and LPC affecting this reduction (p<0.05). Serum levels of interleukin-6 were reduced on day 21, and both endotoxin and interleukin-6 levels were lower on day 42. Notably, a significant interaction was observed between the energy levels and LPC on relative liver weight and endotoxin concentrations in the serum (p<0.05). Conclusion: The study concluded that LPC positively affects growth performance, nutrient digestibility, immune response, and antioxidative capacity in broiler chickens, affirming its value as a beneficial feed additive in poultry nutrition.

키워드

과제정보

This work was supported by the Shandong Provincial Poultry Industry and Technology System (SDAIT-11-08), Shandong Provincial Postdoctoral Program for Innovative Talent (SDBX 2021013), and Youth Fund of Shandong Natural Science Foundation (ZR2022QC139).

참고문헌

  1. Noy Y, Sklan D. Metabolic responses to early nutrition. J Appl Poult Res 1998;7:437-51. https://doi.org/10.1093/japr/7.4.437 
  2. Gheisar MM, Hosseindoust A, Kim HB, Kim IH. Effects of lysolecithin and sodium stearoyl-2-lactylate on growth performance and nutrient digestibility in broilers. Korean J Poult Sci 2015;42:133-7. https://doi.org/10.5536/KJPS.2015.42.2.133 
  3. Wealleans AL, Jansen M, di Benedetto M. The addition of lysolecithin to broiler diets improves growth performance across fat levels and sources: a meta-analysis of 33 trials. Br Poult Sci 2020;61:51-6. https://doi.org/10.1080/00071668.2019.1671955 
  4. Jansen M, Nuyens F, Buyse J, Leleu S, Van Campenhout L. Interaction between fat type and lysolecithin supplementation in broiler feeds. Poul Sci 2015;94:2506-15. https://doi.org/10.3382/ps/pev181 
  5. Zhang B, Li H, Zhao D, Guo Y, Barri A. Effect of fat type and lysophosphatidylcholine addition to broiler diets on performance, apparent digestibility of fatty acids, and apparent metabolizable energy content. Anim Feed Sci Technol 2011;163:177-84. https://doi.org/10.1016/j.anifeedsci.2010.10.004 
  6. Ahmad A, Mughal GA, Abro R, et al. Effect of lipase and lysolecithin supplementation with low energy diet on growth performance, biochemical attributes and fatty acid profile of breast muscle of broiler chickens. Animals (Basel) 2023;13:737. https://doi.org/10.3390/ani13040737 
  7. Wickramasuriya SS, Cho HM, Macelline SP, et al. Effect of calcium stearoyl-2 lactylate and lipase supplementation on growth performance, gut health, and nutrient digestibility of broiler chickens. Asian-Australas J Anim Sci 2020;33:981-91. https://doi.org/10.5713/ajas.19.0595 
  8. Arshad MA, Bhatti SA, Hassan I, Rahman MA, Rehman MS. Effects of bile acids and lipase supplementation in low-energy diets on growth performance, fat digestibility and meat quality in broiler chickens. Braz J Poult Sci 2020;22:1-8. https://doi.org/10.1590/1806-9061-2020-1258 
  9. McCarthy JF, Aherene FX, Okai DB. Use of HCl insoluble ash as an index material for determining apparent digestibility with pigs. Can J Anim Sci 1974;54:107-9. https://doi.org/10.4141/cjas74-016 
  10. Niu ZY, Shi JS, Liu FZ, Wang XH, Gao CQ, Yao LK. Effects of dietary energy and protein on growth performance and carcass quality of broilers during starter phase. Int J Poult Sci 2009;8:508-11. https://doi.org/10.3923/ijps.2009.508.511 
  11. Ge XK, Wang AA, Ying ZX, et al. Effects of diets with different energy and bile acids levels on growth performance and lipid metabolism in broilers. Poult Sci 2019;98:887-95. https://doi.org/10.3382/ps/pey434 
  12. Boontiam W, Jung B, Kim YY. Effects of lysophospholipid supplementation to lower nutrient diets on growth performance, intestinal morphology, and blood metabolites in broiler chickens. Poult Sci 2017;96:593-601. https://doi.org/10.3382/ps/pew269 
  13. Khonyoung D, Yamauchi K, Suzuki K. Influence of dietary fat sources and lysolecithin on growth performance, visceral organ size, and histological intestinal alteration in broiler chickens. Livest Sci 2015;176:111-20. https://doi.org/10.1016/j.livsci.2015.03.011 
  14. Boontiam W, Hyun YK, Jung B, Kim YY. Effects of lysophospholipid supplementation to reduced energy, crude protein, and amino acid diets on growth performance, nutrient digestibility, and blood profiles in broiler chickens. Poult Sci 2019;98:6693-701. https://doi.org/10.3382/ps/pex005 
  15. Overland M, Tokach MD, Cornelius SG, Pettigrew JE, Rust JW. Lecithin in swine diets: I. weanling pigs. J Anim Sci 1993;71:1187-93. https://doi.org/10.2527/1993.7151187x 
  16. Zhao PY, Kim IH. Effect of diets with different energy and lysophospholipids levels on performance, nutrient metabolism, and body composition in broilers. Poult Sci 2017;96:1341-7. https://doi.org/10.3382/ps/pew469 
  17. Honda K, Kamisoyama H, Isshiki Y, Hasegawa S. Effects of dietary fat levels on nutrient digestibility at different sites of chicken intestines. J Poult Sci 2009;46:291-5. https://doi.org/10.2141/jpsa.46.291 
  18. Li BS, Li Z, Sun YZ, Wang SX, Huang BS, Wang JY. Effects of dietary lysolecithin (LPC) on growth, apparent digestibility of nutrient and lipid metabolism in juvenile turbot Scophthalmus maximus L. Aquac Fish 2019;4:61-6. https://doi.org/10.1016/j.aaf.2018.11.003 
  19. Brautigan DL, Li R, Kubicka E, et al. Lysolecithin as feed additive enhances collagen expression and villus length in the jejunum of broiler chickens. Poult Sci 2017;96:2889-98. https://doi.org/10.3382/ps/pex078 
  20. Papadopoulos GA, Poutahidis T, Chalvatzi S, et al. Effects of lysolecithin supplementation in low-energy diets on growth performance, nutrient digestibility, viscosity and intestinal morphology of broilers. Br Poult Sci 2018;59:232-9. https://doi.org/10.1080/00071668.2018.1423676 
  21. Taghavizadeh M, Shekarabi SPH, Mehrgan MS, Islami HR. Efficacy of dietary lysophospholipids (Lipidol™) on growth performance, serum immuno-biochemical parameters, and the expression of immune and antioxidant-related genes in rainbow trout (Oncorhynchus mykiss). Aquaculture 2020;525:735315. https://doi.org/10.1016/j.aquaculture.2020.735315 
  22. Ghazalah A, Abd-Elsamee M, Ibrahim M, et al. Effects of a combination of lysolecithin, synthetic emulsifier, and monoglycerides on growth performance, intestinal morphology, and selected carcass traits in broilers fed low-energy diets. Animals 2021;11:3037. https://doi.org/10.3390/ani11113037 
  23. Park JH, Nguyen DH, Kim IH. Effects of exogenous lysolecithin emulsifier supplementation on the growth performance, nutrient digestibility, and blood lipid profiles of broiler chickens. J Poult Sci 2018;55:190-4. https://doi.org/10.2141/jpsa.0170100 
  24. Lu CH. Application research of substitution of emulsifier for partial oil in the production of broilers [master's thesis]. Nanjing, China: Nanjing Agricultural Univ; 2015. 
  25. Weng M, Zhang W, Zhang Z, et al. Effects of dietary lysolecithin on growth performance, serum biochemical indexes, antioxidant capacity, lipid metabolism and inflammation-related genes expression of juvenile large yellow croaker (Larimichthys crocea). Fish Shellfish Immunol 2022;128:50-9. https://doi.org/10.1016/j.fsi.2022.07.020 
  26. Deng S, Fu A, Junaid M, et al. Nitrogen-doped graphene quantum dots (N-GQDs) perturb redox-sensitive system via the selective inhibition of antioxidant enzyme activities in zebrafish. Biomaterials 2019;206:61-72. https://doi.org/10.1016/j.biomaterials.2019.03.028 
  27. Ayala A, Munoz MF, Arguelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev 2014;2014:360438. https://doi.org/10.1155/2014/360438 
  28. Mucksova J, Chalupsky K, Plachy J, et al. Simultaneous detection of chicken cytokines in plasma samples using the Bio-Plex assay. Poult Sci 2018;97:1127-33. https://doi.org/10.3382/ps/pex411 
  29. Ghareeb K, Awad WA, Soodoi C, Sasgary S, Strasser A, Bohm J. Effects of feed contaminant deoxynivalenol on plasma cytokines and mRNA expression of immune genes in the intestine of broiler chickens. PLoS One 2013;8:e71492. https://doi.org/10.1371/journal.pone.0071492 
  30. Benson S, Engler H, Wegner A, et al. What makes you feel sick after inflammation? predictors of acute and persisting physical sickness symptoms induced by experimental endotoxemia. Clin Pharmacol Ther 2017;102:141-51. https://doi.org/10.1002/cpt.618