DOI QR코드

DOI QR Code

Fascicular Involvement of the Median Nerve Trunk in the Upper Arm: Manifestation as Anterior Interosseous Nerve Syndrome With Unique Imaging Features

  • Jae Eun Park (Department of Radiology, Nowon Eulji Medical Center, Eulji University) ;
  • Darryl B. Sneag (Department of Radiology and Imaging, Hospital for Special Surgery) ;
  • Yun Sun Choi (Department of Radiology, Nowon Eulji Medical Center, Eulji University) ;
  • Sung Hoon Oh (Department of Radiology, Nowon Eulji Medical Center, Eulji University) ;
  • SeongJu Choi (Department of Orthopedic Surgery, Nowon Eulji Medical Center, Eulji University)
  • Received : 2023.12.07
  • Accepted : 2024.02.10
  • Published : 2024.05.01

Abstract

Selective fascicular involvement of the median nerve trunk above the elbow leading to anterior interosseous nerve (AIN) syndrome is a rare form of peripheral neuropathy. This condition has recently garnered increased attention within the medical community owing to advancements in imaging techniques and a growing number of reported cases. In this article, we explore the topographical anatomy of the median nerve trunk and the clinical features associated with AIN palsy. Our focus extends to unique manifestations captured through MRI and ultrasonography (US) studies, highlighting noteworthy findings, such as nerve fascicle swelling, incomplete constrictions, hourglass-like constrictions, and torsions, particularly in the posterior/posteromedial region of the median nerve. Surgical observations have further enhanced the understanding of this complex neuropathic condition. High-resolution MRI not only reveals denervation changes in the AIN and median nerve territories but also illuminates these alterations without the presence of compressing structures. The pivotal roles of high-resolution MRI and US in diagnosing this condition and guiding the formulation of an optimal treatment strategy are emphasized.

Keywords

References

  1. Sneag DB, Aranyi Z, Zusstone EM, Feinberg JH, Queler SC, Nwawka OK, et al. Fascicular constrictions above elbow typify anterior interosseous nerve syndrome. Muscle Nerve 2020;61:301-310
  2. Jung YY, Choi YS, Lee CH, Kwon O, Kim M. Selective fascicular involvement of the median nerve trunk causing pseudoanterior interosseous nerve syndrome: ultrasound and MR imaging features. Yonsei Med J 2020;61:547-552
  3. Godel T, Pham M, Kele H, Kronlage M, Schwarz D, Brunee M, et al. Diffusion tensor imaging in anterior interosseous nerve syndrome - functional MR neurography on a fascicular level. Neuroimage Clin 2019;21:101659
  4. Noda Y, Sekiguchi K, Tokuoka H, Oda T, Hamaguchi H, Kanda F, et al. Ultrasonographic findings of proximal median neuropathy: a case series of suspected distal neuralgic amyotrophy. J Neurol Sci 2017;377:1-5
  5. Pham M, Baumer P, Meinck HM, Schiefer J, Weiler M, Bendszus M, et al. Anterior interosseous nerve syndrome: fascicular motor lesions of median nerve trunk. Neurology 2014;82:598-606
  6. Aranyi Z, Csillik A, Devay K, Rosero M, Barsi P, Bohm J, et al. Ultrasonographic identification of nerve pathology in neuralgic amyotrophy: enlargement, constriction, fascicular entwinement, and torsion. Muscle Nerve 2015;52:503-511
  7. Pan Y, Wang S, Zheng D, Tian W, Tian G, Ho PC, et al. Hourglass-like constrictions of peripheral nerve in the upper extremity: a clinical review and pathological study. Neurosurgery 2014;75:10-22
  8. Yasunaga H, Shiroishi T, Ohta K, Matsunaga H, Ota Y. Fascicular torsion in the median nerve within the distal third of the upper arm: three cases of nontraumatic anterior interosseous nerve palsy. J Hand Surg Am 2003;28:206-211
  9. Nagano A, Shibata K, Tokimura H, Yamamoto S, Tajiri Y. Spontaneous anterior interosseous nerve palsy with hourglasslike fascicular constriction within the main trunk of the median nerve. J Hand Surg Am 1996;21:266-270
  10. Chin DH, Meals RA. Anterior interosseous nerve syndrome. J Hand Surg Am 2001;1:249-257
  11. Caetano EB, Vieira LA, Sabongi Neto JJ, Caetano MBF, Sabongi RG. Anterior interosseous nerve: anatomical study and clinical implications. Rev Bras Ortop 2018;53:575-581
  12. Davidge KM, Sammer DM. Median nerve entrapment and injury. In: Mackinnon SE, ed. Nerve surgery. 1st ed. New York: Thieme, 2015:208-209
  13. van Alfen N, van Engelen BG. The clinical spectrum of neuralgic amyotrophy in 246 cases. Brain 2006;129(Pt 2):438-450
  14. Qi HT, Wang XM, Li SY, Wang GB, Wang DH, Wang ZT, et al. The role of ultrasonography and MRI in patients with non-traumatic nerve fascicle torsion of the upper extremity. Clin Radiol 2013;68:e479-e483
  15. Nakashima Y, Sunagawa T, Shinomiya R, Ochi M. Highresolution ultrasonographic evaluation of "hourglass-like fascicular constriction" in peripheral nerves: a preliminary report. Ultrasound Med Biol 2014;40:1718-1721
  16. Lundborg G. Commentary: hourglass-like fascicular nerve compressions. J Hand Surg Am 2003;28:212-214
  17. Deng H, Lu B, Yin C, Xu Y, Ding Y, Mi Y, et al. The effectiveness of ultrasonography in the diagnosis of spontaneous hourglasslike constriction of peripheral nerve in the upper extremity. World Neurosurg 2020;134:e103-e111
  18. Maldonado AA, Amrami KK, Mauermann ML, Spinner RJ. Reinterpretation of electrodiagnostic studies and magnetic resonance imaging scans in patients with nontraumatic "isolated" anterior interosseous nerve palsy. Plast Reconstr Surg 2016;138:1033-1039
  19. Sneag DB, Rancy SK, Wolfe SW, Lee SC, Kalia V, Lee SK, et al. Brachial plexitis or neuritis? MRI features of lesion distribution in Parsonage-Turner syndrome. Muscle Nerve 2018;58:359-366
  20. Cejas C, Pastor Rueda JM, Hernandez Pinzon J, Stefanoff N, Barroso F. Neuralgic amyotrophy detected by magnetic resonance neurography: subclinical, bilateral, and multifocal brachial plexus involvement. Neurol Res 2023;45:283-289
  21. Chhabra A, Madhuranthakam AJ, Andreisek G. Magnetic resonance neurography: current perspectives and literature review. Eur Radiol 2018;28:698-707
  22. Sneag DB, Saltzman EB, Meister DW, Feinberg JH, Lee SK, Wolfe SW. MRI bullseye sign: an indicator of peripheral nerve constriction in parsonage-turner syndrome. Muscle Nerve 2017;56:99-106
  23. Kim SJ, Hong SH, Jun WS, Choi JY, Myung JS, Jacobson JA, et al. MR imaging mapping of skeletal muscle denervation in entrapment and compressive neuropathies. Radiographics 2011;31:319-332
  24. Ochi K, Horiuchi Y, Tazaki K, Takayama S, Matsumura T. Fascicular constrictions in patients with spontaneous palsy of the anterior interosseous nerve and the posterior interosseous nerve. J Plast Surg Hand Surg 2012;46:19-24
  25. Ulrich D, Piatkowski A, Pallua N. Anterior interosseous nerve syndrome: retrospective analysis of 14 patients. Arch Orthop Trauma Surg 2011;131:1561-1565
  26. Rodner CM, Tinsley BA, O'Malley MP. Pronator syndrome and anterior interosseous nerve syndrome. J Am Acad Orthop Surg 2013;21:268-275
  27. Krishnan KR, Sneag DB, Feinberg JH, Wolfe SW. Anterior interosseous nerve syndrome reconsidered: a critical analysis review. JBJS Rev 2020;8:e2000011