Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Giant Malignant Peripheral Nerve Sheath Tumor of Neck

경부의 거대 악성 말초 신경성 종양 예

  • Choonghun Han (Department of Otorhinolaryngology-Head & Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Hanaro Park (Department of Otorhinolaryngology-Head & Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine)
  • 한충헌 (성균관대학교 의과대학 삼성창원병원 이비인후과학교실) ;
  • 박하나로 (성균관대학교 의과대학 삼성창원병원 이비인후과학교실)
  • Received : 2023.08.21
  • Accepted : 2024.01.18
  • Published : 2024.05.30
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Abstract

Malignant peripheral nerve sheath tumor (MPNST) is an extremely rare sarcoma of soft tissue. It is locally invasive, frequently recurred and metastasizes distantly, therefore has a very poor prognosis. the most involved sites are human body and extremities, and MPNST occurs and involved very rarely in the parapharynx of neck. MPNST does not react to radiotherapy and chemotherapy, therefore complete surgical resection is the most important treatment. Since immunohistochemical staining is essential for the final diagnosis, it is common to be confirmed after surgery. We report a case of giant MPNST without symptom in the head and neck involving the right parapharynx with multiple distant metastases in a 74-year-old patient on a review of the literature.

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References

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