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Angioinvasive Mucormycosis Mimicking Mass and Pulmonary Thromboembolism in a Patient with Myelodysplastic Syndrome: A Case Report

골수이형성 증후군 환자에서 발생한 종괴와 폐색전증을 모방하는 혈관침습성 점막진균증: 증례 보고

  • Hyo Ju Na (Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine) ;
  • Song Soo Kim (Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine) ;
  • Shinhye Cheon (Division of Infectious Diseases, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine) ;
  • Jin Hwan Kim (Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine) ;
  • Hyeyoung Kwon (Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine)
  • 나효주 (충남대학교 의과대학 충남대학교병원 영상의학과) ;
  • 김성수 (충남대학교 의과대학 충남대학교병원 영상의학과) ;
  • 천신혜 (충남대학교 의과대학 충남대학교병원 감염내과) ;
  • 김진환 (충남대학교 의과대학 충남대학교병원 영상의학과) ;
  • 권혜영 (충남대학교 의과대학 충남대학교병원 영상의학과)
  • Received : 2023.02.13
  • Accepted : 2023.09.08
  • Published : 2024.03.01

Abstract

Mucormycosis encompasses a range of fungal infections that can impact various organs. Although pulmonary mucormycosis is relatively rare, it poses a significant threat, particularly to individuals with compromised immune systems. Pulmonary mucormycosis presents with various radiological manifestations. Notably, the involvement of the angioinvasive pulmonary artery in pulmonary mucormycosis cases has seldom been documented. In this report, we showcase the radiological characteristics of angioinvasive mucormycosis, which can mimic pulmonary thromboembolism or a pulmonary artery tumor, in a patient diagnosed with myelodysplastic syndrome.

Mucormycosis는 Mucorales에 의해 유발되는 진균 감염으로, 다양한 장기를 침범할 수 있으며 그중에서도 폐점균증은 드물지만 특히 면역 저하 환자에서 생명을 위협하는 기회 감염이다. 폐점균증의 영상 소견은 다양하지만, 폐점액진균증 환자에서 점점 커지는 폐동맥색전증을 모방하는 경우는 드물게 보고되었다. 저자들은 골수이형성 증후군 환자에서 종괴와 폐색전증을 모방한 혈관 침습성 점막 진균증의 증례에 대해 보고하고자 한다.

Keywords

References

  1. Hammer MM, Madan R, Hatabu H. Pulmonary mucormycosis: radiologic features at presentation and over time. AJR Am J Roentgenol 2018;210:742-747
  2. Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 2012;54(Suppl 1):S23-S34
  3. Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 9th ed. Philadelphia, PA: Elsevier 2019
  4. Fernandez JF, Maselli DJ, Simpson T, Restrepo MI. Pulmonary mucormycosis: what is the best strategy for therapy? Respir Care 2013;58:e60-e63
  5. Mititelu R, Bourassa-Blanchette S, Sharma K, Roth V. Angioinvasive mucormycosis and paradoxical stroke: a case report. JMM Case Rep 2016;3:e005048
  6. Agrawal R, Yeldandi A, Savas H, Parekh ND, Lombardi PJ, Hart EM. Pulmonary mucormycosis: risk factors, radiologic findings, and pathologic correlation. Radiographics 2020;40:656-666