Nuclear Engineering and Technology

Korean Nuclear Society (한국원자력학회)
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Evaluation of exposure to ionizing radiation of medical staff performing procedures with glucose labeled with radioactive fluorine - 18F-FDG

  • Received : 2023.07.25
  • Accepted : 2023.10.04
  • Published : 2024.01.25
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Abstract

Employees of nuclear medicine facilities performing medical procedures with the use of open radioactive sources require continuous detailed control of exposure to ionizing radiation. Thermoluminescent (TL) detectors placed in dosimeters: for the whole body, for lenses, ring and wrist dosimeters were used to assess exposure. The highest whole-body exposure of (1.70 ± 1.09) µSv/GBq was recorded in nurses administering radiopharmaceutical to patients. The highest exposure to lenses and fingers was recorded for employees of the quality control zone and it was (8.08 ± 2.84) µSv/GBq and a maximum of (1261.46 ± 338.93) µSv/GBq, respectively. Workers in the production zone received the highest doses on their hands, i.e. (175.67 ± 13.25) µSv/GBq. The measurements performed showed that the analyzed workers may be classified as exposure category A. Wrist dosimeters are not recommended for use in isotope laboratories due to underestimation of ionizing radiation doses. Appropriately selected shields, which significantly reduce the dose received by employees, must be used in isotope laboratories. Periodic measurements confirmed that the appropriate optimization of exposure reduces the radiation doses received by employees.

Keywords

Acknowledgement

The study was conducted in accordance with the Declaration of Helsinki, and approved by the Bioethical Commission of the Medical University of Lodz, Poland (approval No RNN/144/23/KE, date 16 May 2023).

References

  1. M. Biegala, T. Jakubowska, Levels of exposure to ionizing radiation among the personnel engaged in cyclotron operation and the personnel engaged in the production of radiopharmaceuticals, based on radiation monitoring system, Radiat. Protect. Dosim. 189 (1) (2020 Jul 7) 56-62, https://doi.org/10.1093/rpd/ncaa012. PMID: 32115636; PMCID: PMC7703741. 
  2. M. Biegala, T. Jakubowska, M. Wrzesien, L. Albiniak, Exposure to ionizing radiation by service personnel working with cyclotrons used to produce radiopharmaceuticals in PET diagnostics, Int. J. Occup. Med. Environ. Health 35 (6) (2022 Dec 15) 753-760, https://doi.org/10.13075/ijomeh.1896.01992. Epub 2022 Sep 5. PMID: 36069588. 
  3. F.A. Mettler Jr., W. Huda, T.T. Yoshizumi, M. Mahesh, Effective doses in radiology and diagnostic nuclear medicine: a catalog, Radiology 248 (1) (2008 Jul) 254-263, https://doi.org/10.1148/radiol.2481071451. PMID: 18566177. 
  4. D. Villoing, D. Borrego, D.L. Preston, B.H. Alexander, A. Rose, M. Salasky, M. S. Linet, C. Lee, C.M. Kitahara, Trends in occupational radiation doses for U.S. Radiologic technologists performing general radiologic and nuclear medicine procedures, 1980-2015, Radiology 300 (3) (2021 Sep) 605-612, https://doi.org/10.1148/radiol.2021204501. Epub 2021 Jun 22. PMID: 34156301; PMCID: PMC8409105. 
  5. M. Wrzesien, 18F-FDG production procedures as a source of eye lens exposure to radiation, J. Radiol. Prot. 38 (1) (2018 Feb 15) 382-393, https://doi.org/10.1088/1361-6498/aaa287. Epub ahead of print. PMID: 29447122. 
  6. M. Wrzesien, L. Krolicki, L. Albiniak, J. Olszewski, Is eye lens dosimetry needed in nuclear medicine? J. Radiol. Prot. 38 (2) (2018 Jun) 763-774, https://doi.org/10.1088/1361-6498/aabef5. Epub 2018 Apr 18. PMID: 29667600. 
  7. S. Basu, S. Hess, P.E. Nielsen Braad, B.B. Olsen, S. Inglev, P.F. Hoilund-Carlsen, The basic principles of FDG-PET/CT imaging, Pet. Clin. 9 (4) (2014 Oct) 355-370, https://doi.org/10.1016/j.cpet.2014.07.006. Epub 2014 Aug 5. PMID: 26050942. 
  8. T. Kron, P. Lonski, E.G. Yukihara, Thermoluminescence dosimetry (TLD) in medicine: five 'W'S and one HOW, Radiat. Protect. Dosim. 192 (2) (2020 Dec 30) 139-151. 
  9. T. Rivera, Thermoluminescence in medical dosimetry, Appl. Radiat. Isot. 71 (Suppl) (2012 Dec) 30-34, https://doi.org/10.1016/j.apradiso.2012.04.018. Epub 2012 Apr 30. PMID: 22633888. 
  10. T. Niewiadomski, P. Bilski, M. Budzanowski, P. Olko, E. Ryba, Progress in Thermoluminescent Dosimetry for Radiation Protection and Medicine, vol. 41, Cracow, Nukleonika: Institute of Nuclear Physics, 1996, pp. 93-104. 
  11. M.P.R. Waligorski, J. Lesiak, E. Babula, E. Byrski, E. Ryba, P. Olko, P. Bilski, Application of individually calibrated solid LiF:Mg, Ti (MTS-N) detectors in clinical dosimetry, Radiat. Protect. Dosim. 85 (1-4) (1999) 377-380. 
  12. International Organization for Standardization (ISO), X and Gamma Reference Radiation for Calibrating Dosemeters and Doserate Meters and Determining Their Response as a Function of Photon Energy. Part 3: Calibration of Area and Personal Dosemeters and the Measurement of Their Response as a Function of Energy and Angle of Incidence (Geneva: ISO), International Standard ISO- 4037-3, 1999. 
  13. National Research Council of the National Academies, Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2, The National Academies Press, Washington, DC, 2006, p. 245. 
  14. M. Wrzesien, L. Albiniak, M. Biegala, The structure of Hp(0.07) values obtained by the nuclear medicine personnel during 18f-FDG production and injection, Radiat. Protect. Dosim. 184 (2) (2019 Aug 1) 224-229. 
  15. F. Vanhavere, et al., Optimization of Radiation Protection of Medical Staff EURADOS Report 2012-02 Braunschweig, 2012. 
  16. P. Covens, D. Berus, N. Buls, P. Clerinx, F. Vanhavere, Personal dose monitoring in hospitals: global assessment, critical applications and future needs, Radiat. Protect. Dosim. 124 (3) (2007) 250-258. 
  17. B. Pavicar, J. Davidovic, B. Petrovic, G. Vuleta, S. Trivic, V. Sajinovic, N. Egeljic-Mihailovic, N. Todorovic, B. Predojevic, Nuclear medicine staff exposure to ionising radiation in 18F-FDG PET/CT practice: a preliminary retrospective study, Arh. Hig. Rada. Toksikol. 72 (3) (2021 Sep 28) 216-224, https://doi.org/10.2478/aiht-2021-72-3517. PMID: 34587667; PMCID: PMC8576747. 
  18. J. Wang, F. Wang, Y. Liu, Y. Xu, J. Liang, Z. Su, Estimation of nuclear medicine exposure measures based on intelligent computer processing, 2021, J. Healthc. Eng. (2021 Sep 27), 4102183, https://doi.org/10.1155/2021/4102183. PMID: 34616531; PMCID: PMC8490043. 
  19. A. Carnicer, et al., Hand exposure in diagnostic nuclear medicine with 18F- and 99mTc-labelled radiopharmaceuticals - results of the ORAMED project, Radiat. Meas. 46 (2011) 1277-1282.