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홍삼가공식품의 식품유형별 및 제형별 진세노사이드 함량 비교

Comparative Analysis of Ginsenoside Content in Processed Red Ginseng Foods Based on Food Type and Formulation

  • Yun-Jeong Yi (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Min-Su Chang (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • In-Sook Lee (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Hyun-Jeong Kim (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Hyun-Jeong Jang (Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • In-Sook Hwang (Seoul Metropolitan Government Research Institute of Public Health and Environment)
  • 투고 : 2023.12.27
  • 심사 : 2024.04.18
  • 발행 : 2024.04.30

초록

서울 시내 유통점과 온라인 쇼핑몰에서 구입한 홍삼함유식품 66건과 건강기능식품 홍삼제품 35건의 기능 성분인 진세노사이드 함량을 비교·분석하였다. 홍삼함유식품 66건 중 전통시장에서 구입한 2건은 진세노사이드가 검출되지 않았고 64건의 제품에서는 진세노사이드 함량에 대한 기준은 없지만 일일 섭취량 기준 0.55-71.56 mg을 함유하고 있었다. 건강기능식품의 홍삼제품은 진세노사이드 평균 함량이 분말형 제품을 제외하고 일일 섭취량 기준 18.23 mg으로 홍삼함유식품의 8.80 mg 보다 약 2배 정도가 많았다. 홍삼과 흑삼 비교 시 진세노사이드 함량은 홍삼 제품이 흑삼 제품보다 많거나 비슷하였으나 분말형 제품의 경우 흑삼 제품이 2배 많았다. 제형별 진세노사이드 평균 함량은 일일섭취량 기준 농축액 21.95 mg으로 가장 많고 분말 형태 12.54 mg, 스틱형 7.36 mg, 파우치형이 4.10 mg 순이었다. 흑삼제품은 고기능성으로 알려져 있으나 대부분 일반 식품으로 판매되고 있어 건강기능식품 수준의 관리와 규제가 필요할 것으로 보이며 흑삼의 규격기준 설정 이후에는 흑삼제품의 기능성분 함량 재평가가 필요할 것으로 판단된다. 스틱형이나 농축액 제품의 경우 건강기능식품뿐만 아니라 일반식품인 액상차, 홍삼음료로도 널리 판매되고 있어 식품유형 표시를 명확히 해야 할 것으로 보인다. 최근 면역력 향상을 위한 소비자의 관심 증가로 다양한 건강기능식품의 수요가 늘어나고 있다. 따라서 홍삼을 함유한 식품을 섭취 목적에 맞게 선택할 수 있도록 정확한 함량정보 제공을 위해 다양한 제품에 대한 지속적인 품질평가가 필요하다.

Red ginseng is manufactured as a health-functional food and is also present in various food types and in different product forms. However, there is currently no standardized regulation of ginsenoside content in foods containing red ginseng. In the present study, we analyzed the ginsenoside content of 66 red ginseng-containing foods and 35 health-functional foods collected online and directly from the market. The ginsenoside content was assessed using liquid chromatography (LC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. The ginsenoside content of the various food types ranged 0.0 (not detected)-71.567 mg per daily intake of foods containing red ginseng. Sugar-preserved foods had the highest ginsenoside content, followed by solid teas, liquid teas, and red ginseng beverages. For health-functional foods, the ginsenoside content ranged 3.4-58.5 mg per daily intake, with levels ranging 83-607% of the indicated amounts. All values met the established standards. Upon comparing red ginseng health-functional foods and red ginseng-containing foods, the average ginsenoside content was determined to be 18.21 and 8.79 mg, respectively, thus being nearly twice as high in health-functional foods. However, there was a minimal difference between the ginsenoside content of red and black ginseng, with values of 11.84 and 12.63 mg, respectively. These findings provide insights on the variations in ginsenoside content of red and black ginseng in various food forms. This information is expected to be valuable for future regulations and consumer choice of products containing red ginseng.

키워드

참고문헌

  1. Ministry of Food and Drug Safety (MFDS), (2024, March 6). Korea health functional food code. Retrieved from https://various.foodsafetykorea.go.kr/fsd/#/ext/Document/FF 
  2. Jeong, H.C., Hong, H.D., Kim, Y.C., Rho, J., Kim, K.T., Cho, C.W., The research trend of ginsengprocessing technology and the status of ginseng industry. Food Sci. Ind., 45, 59- 67 (2012). 
  3. Kim, S.T., Heo, C.H., Kim, S.H., Lee, W.J., Jang, S.K., Joo, S.S., Quality stability of products containing fermented ginseng berry extracts. J. Food Hyg. Saf., 34, 473-479 (2019).  https://doi.org/10.13103/JFHS.2019.34.5.473
  4. Kim, D.C., Lee, T.J., In, M.J., Potential of proteolytic enzyme treatment for production of Korean redginseng extract. J. Appl. Biol. Chem., 62, 385-389 (2019).  https://doi.org/10.3839/jabc.2019.053
  5. Jeong, S.H., Im, W.H., Lim, Y.H., Kim, H.J., Ginsenoside contents and biological activities of blackginseng Pung-gi. J Korean. Immuno-Yakchim Soc., 5, 9-17 (2016). 
  6. Lee, G.D., Optimization of formation of the ginsenoside Rg3 in black ginseng steamed with acetic acid solution. Korean J. Food Preserv., 27, 66-73 (2020).  https://doi.org/10.11002/kjfp.2020.27.1.66
  7. Nam, K.Y., Lee, N.R., Moon, B.D., Song, G.Y., Shin, H.S., Choi, J.E., Changes of ginsenosides and color from black ginsengs prepared by steaming-drying cycles. Korean J. Med. Crop Sci., 20, 27-35(2012).  https://doi.org/10.7783/KJMCS.2012.20.1.027
  8. Ministry of Food and Drug Safety (MFDS), (2024, March 6). Trends in food and drug production and consumption based on food and drug statistics. Retrieved from https://www.mfds.go.kr/brd/m_382/list.do 
  9. Ipsos, (2024, March 6). South Korea 2021 leading the way: resilience, perspectives & innovations. Retrieved from https://www.ipsos.com/sites/default/files/ct/publication/documents/2021-04/ipsosflair-SouthKorea-eng.pdf 
  10. Ministry of Food and Drug Safety (MFDS), (2024, March 6). Food code. Retrieved fromhttps://various.foodsafetykorea.go.kr/fsd/#/ext/Document/FC 
  11. National Agricultural Products Quality Management Service (NAQS), (2024,March 6). Notification No. 2020-6. Retrieved https://www.naqs.go.kr/mobile/multiboard/board/detail.naqs?menu=MN30792&groupno=282&cate=0&page=1&schTye=&schKeyword=&seq=55399 
  12. Kim, H.J., Kwak, I.A., Kim, H.J., Ahn, J.S., Son, Y.B., A study on the amendment scheme of ginsenoside content standard regulation for red ginseng products in Korea. J. Food Hyg. Saf., 28, 24-30 (2013).  https://doi.org/10.13103/JFHS.2013.28.1.024
  13. Yu, J., Jang, I.B., Moon, J.W., Jang, I.B., Lee, S.W., Suh, S.J., Physicochemical characteristics of a 4-year-old ginseng based on steaming temperatures and times. Korean J. Med. Crop. Sci., 27, 86-95 (2019).  https://doi.org/10.7783/KJMCS.2019.27.2.86
  14. Lee, E.S., You, K.M., Kim, S.Y., Lee, K.S., Park, S.J., Jeon, B.S., Park, J.T., Hong, S.T., A Study on the utilization of byproducts from honeyed red ginseng: optimization of total ginsenoside extraction using response surface methodology. Food Eng. Prog., 21, 79-87 (2017).  https://doi.org/10.13050/foodengprog.2017.21.1.79
  15. Kim, J.P., Kim, J.H., Gang, G.L., Yang, Y.S., Hong, S.J., Kim, E.S., Moon, Y.W., Lee, J.C., Song, H.J., Chung, J.K., A survey on the content and safety of red ginseng products. Korean J. Food Sci. Technol., 43, 413-418 (2011).  https://doi.org/10.9721/KJFST.2011.43.4.413
  16. Ministry of Food and Drug Safety (MFDS), 2020. Ingredients of ginseng and red ginseng, Notice No. 2020-128. MFDS, Cheongju, Korea, pp. 64-67. 
  17. Ministry of Food and Drug Safety (MFDS), 2020. Ginsenocide (No, 3-55), Notice No. 2018-12. MFDS, Cheongju, Korea, pp. 384-388. 
  18. Association of Official Agricultural Chemists (AOAC), (2024, March 6). How to meet ISO 17025 requirements for method verification. Retrieved from https://www.aoac.org/wp-content/uploads/2019/09/ALACC-method-verification.pdf 
  19. Kim, D.K., Choi, S.J., Lee, M.Y., Yun, E.S., 2015. 2015 KFN international symposium and annual meeting : ginsenoside and sugar content of red ginseng products, The Korean Society of Food Science and Nutrition, Busan, Korea, pp.267. 
  20. Lee, K.H., Lee, D.Y., Lee, S.E., Nam, K.Y., Hwang, G.B., Kim, H.D., Lee, J.W., Choi, J.H., Ahn, Y.S., Kim, S.Y., Kim, G.S., Evaluation onextraction conditions and HPLC analysis method for ginsenosides in Panax ginseng. Korean J. Med. Crop. Sci., 24, 47-54 (2016).  https://doi.org/10.7783/KJMCS.2016.24.1.47
  21. Consumer 24, (2024, March 6). Red ginseng concentrate. Retrieved from https://www.consumer.go.kr/user/ftc/consumer/cnsmrBBS/79/selectInfoRptDetail.do?infoId=A1078607&page=1&row=10&searchCnsmrClId=&searchCnsmrClType=&upper-ProductClId=&searchGbn=REGIST_DT&cntntsNm=&upperCntntsNm=&rnum=1&infoTyIdList=&cntntsId=00000566&infoRealmIdList=&infoPrdlstIdList=&searchRange=searchRange-All&searchKeyword=%ED%99%8D%EC%82%BC 
  22. Ministry of Food and Drug Safety (MFDS), (2024, March 6). Notice regarding food productmanufacturing notification (black ginseng). Retrieved from https://www.mfds.go.kr/brd/m_841/view.do?seq=31419&srchFr=&srchTo=&srchWord= &srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=91 
  23. Kwon, S.W., (2024, March 6). Investigation for establishing the standardization of black ginseng. Retrieved from https://doi.org/10.23000/TRKO201700017629 
  24. Nam, K.Y., Choi, J.E., Hong, S.C., Pyo, M.K., Park, J.D., Recent progress in research on anticanceractivities of Ginsenoside-Rg3. Korean J. Pharmacogn., 45, 1-10 (2014). 
  25. Kim, E.H., Kim, S.W., Park, S.J., Kim, S., Yu, K.M., Kim, S.G., Lee, S.H., Seo, Y.K., Cho, N.H., Kang, K., Soung, D.Y., Choi, Y.K., Greater efficacy of blackginseng (CJ EnerG) over red ginseng against lethal influenza A virus infection. Nutrients, 11, 1879 (2019).