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인천광역시 유통 한약재의 잔류농약 실태 조사 및 위해평가

Monitoring and Risk Assessment of Pesticide Residues in Herbal Medicines in Incheon

  • 강민정 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 권성희 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 김선회 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 염미숙 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 박병규 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 이희정 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 김지형 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 주광식 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 허명제 (인천광역시 보건환경연구원 삼산농산물검사소) ;
  • 권문주 (인천광역시 보건환경연구원 삼산농산물검사소)
  • Min-jeong Kang (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Sung-Hee Kwon (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Sun-Hoi Kim (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Mi-Sook Yeom (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Byung-Kyu Park (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Hee-jeong Lee (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Ji-Hyeung Kim (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Kwang-sig Joo (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Myung-je Heo (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment) ;
  • Mun-ju Kwon (Department of Samsan Agricultural Products Inspection Center, Incheon Metropolitan City Institute of Public Health and Environment)
  • 투고 : 2024.01.31
  • 심사 : 2024.04.02
  • 발행 : 2024.04.30

초록

본 연구에서는 인천광역시에서 유통 중인 한약재의 안전성을 확인하기 위해 24품목의 50건을 대상으로 345종의 잔류농약을 분석하였다. 잔류농약은 미량으로도 인체의 건강에 해를 가할 수 있는 유해 물질로 주의가 필요하다. 기준 규격외 다양한 잔류농약 확인을 위해, QuEChERS법으로 전처리후 분석한 결과, 7품목 24건(48%)의 한약재에서 총 22종의 잔류농약이 검출되었으며, 농약이 검출된 한약재는 천궁, 택사, 당귀, 백지 순으로 많았다. 검출 농약 중 2건을 제외하고는 모두 기준이 설정되어 있지 않은 농약이었으나, 위해 평가 결과 안전한 수준으로 확인되었다. 또한, 동일 품목에서 다빈도로 검출되는 농약을 확인하여, 해당 품목의 지속적인 잔류농약 모니터링의 필요성을 시사하였으며, 대한약전의 전처리법에 따른 비교분석에서도 동일한 농약이 검출되어, QuEChERS법을 이용한 생약의 잔류농약 분석 가능성을 제시하였다. 결과적으로, 소비자 안전을 위해서 기준규격 잔류농약 항목 외에도, 생약에 대한 지속적인 잔류농약 모니터링과 신뢰성 높은 고효율 분석법 개발 연구가 계속 필요할 것이다.

This study investigated the levels of 345 pesticide residues in 50 herbal medicines sold in Incheon metropolitan city to determine their safety. Pesticide residues are harmful substances that can cause serious health problems owing to their toxicity and carcinogenicity. The analysis of pesticide residues in the samples was conducted using the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method, known for its high analysis efficiency, to analyze a wide range of pesticides for which no standards have been set. The analysis was cross-validated with the pretreatment method outlined in the Korea Pharmacopoeia. Among the 50 samples encompassing 24 different herbs, 22 pesticide residues were detected in 24 samples, covering 7 distinct herbs, resulting in a detection rate of 48%. It is noteworthy that, except for two cases, all detected pesticides were those for which no standards were set. However, after conducting a risk evaluation considering the daily dosage of herb, it was determined that the levels of pesticide residues were within safe limits. Pesticides with high frequency within the same category of herbs were detected, indicating the necessity for continuous monitoring and regulation. In addition, comparative analysis using the pretreatment method outlined in the Korean Pharmacopoeia, yielded similar results, suggesting the possibility of analyzing pesticide residues in herbs using the QuEChERS method. The study emphasizes the importance of continuous monitoring of pesticide residues in herbs and the development of high-efficiency reliability analysis methods should continue to ensure consumer safety.

키워드

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