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Factors Associated with Gastric and Duodenal Neuroendocrine Tumor Development

  • Kwangwoo Nam (Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine) ;
  • Su Youn Nam (Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University)
  • Received : 2024.02.26
  • Accepted : 2024.03.23
  • Published : 2024.04.20

Abstract

The incidence and prevalence of upper gastrointestinal neuroendocrine tumors (NETs), including gastric NETs (GNETs) and duodenal NETs (DNETs), have been gradually increasing. These trends may be associated with the increased use of health checkups, which includes upper endoscopy, in conjunction with better disease recognition. However, the clinical factors associated with GNETs and DNETs remain unknown; previous studies revealed discrepancies. Recently, metabolic disorders have been indicated as potential factors that are associated with GNETs and DNETs. This review summarizes the results of previous studies and briefly introduces the results of a recent Korean multicenter study on the factors associated with GNETs and DNETs.

Keywords

Acknowledgement

This study was supported by the Korean Society of Gastrointestinal Cancer Research (2021). The funding source did not play any role in the planning or implementation of this study, interpreting the results, or writing the manuscript. The views and opinions expressed are those of the authors and do not necessarily reflect those of the supporting institutions.

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