Acknowledgement
The authors thank Mx. Yoko Sasaki, animal technician, for directing animal care and use at the Laboratory of Biopharmaceutics at Chiba University. The authors also thank Kumi Honda (Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd, Tokyo, Japan) for performing the blood chemistry analysis. We acknowledge Editage (www. edita ge. com) for English language editing.
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