DOI QR코드

DOI QR Code

Mortality Burden Due to Short-term Exposure to Fine Particulate Matter in Korea

  • Jongmin Oh (Department of Environmental Medicine, Ewha Womans University College of Medicine) ;
  • Youn-Hee Lim (Section of Environmental Health, Department of Public Health, University of Copenhagen) ;
  • Changwoo Han (Department of Preventive Medicine, Chungnam National University College of Medicine) ;
  • Dong-Wook Lee (Department of Occupational and Environmental Medicine, Inha University Hospital) ;
  • Jisun Myung (Inha Research Institute for Medical Science, Inha University College of Medicine) ;
  • Yun-Chul Hong (Department of Human Systems Medicine, Seoul National University College of Medicine) ;
  • Soontae Kim (Department of Environmental and Safety Engineering, Ajou University) ;
  • Hyun-Joo Bae (Division of Environmental Health, Korea Environment Institute)
  • 투고 : 2023.11.13
  • 심사 : 2024.02.22
  • 발행 : 2024.03.31

초록

Objectives: Excess mortality associated with long-term exposure to fine particulate matter (PM2.5) has been documented. However, research on the disease burden following short-term exposure is scarce. We investigated the cause-specific mortality burden of short-term exposure to PM2.5 by considering the potential non-linear concentration-response relationship in Korea. Methods: Daily cause-specific mortality rates and PM2.5 exposure levels from 2010 to 2019 were collected for 8 Korean cities and 9 provinces. A generalized additive mixed model was employed to estimate the non-linear relationship between PM2.5 exposure and cause-specific mortality levels. We assumed no detrimental health effects of PM2.5 concentrations below 15 ㎍/m3. Overall deaths attributable to short-term PM2.5 exposure were estimated by summing the daily numbers of excess deaths associated with ambient PM2.5 exposure. Results: Of the 2 749 704 recorded deaths, 2 453 686 (89.2%) were non-accidental, 591 267 (21.5%) were cardiovascular, and 141 066 (5.1%) were respiratory in nature. A non-linear relationship was observed between all-cause mortality and exposure to PM2.5 at lag0, whereas linear associations were evident for cause-specific mortalities. Overall, 10 814 all-cause, 7855 non-accidental, 1642 cardiovascular, and 708 respiratory deaths were attributed to short-term exposure to PM2.5. The estimated number of all-cause excess deaths due to short-term PM2.5 exposure in 2019 was 1039 (95% confidence interval, 604 to 1472). Conclusions: Our findings indicate an association between short-term PM2.5 exposure and various mortality rates (all-cause, non-accidental, cardiovascular, and respiratory) in Korea over the period from 2010 to 2019. Consequently, action plans should be developed to reduce deaths attributable to short-term exposure to PM2.5.

키워드

과제정보

JO was supported as a trainee of the environmental health training program provided by the Environmental Health Centre of the Catholic University of Korea, funded by the Ministry of Environment, Republic of Korea (2023).

참고문헌

  1. Fuller R, Landrigan PJ, Balakrishnan K, Bathan G, Bose-O'Reilly S, Brauer M, et al. Pollution and health: a progress update. Lancet Planet Health 2022;6(6):e535-e547. https://doi.org/10.1016/S2542-5196(22)00090-0 
  2. Cohen AJ, Brauer M, Burnett R, Anderson HR, Frostad J, Estep K, et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet 2017;389(10082):1907-1918. https://doi.org/10.1016/S0140-6736(17)30505-6 
  3. Burnett R, Chen H, Szyszkowicz M, Fann N, Hubbell B, Pope CA 3rd, et al. Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter. Proc Natl Acad Sci U S A 2018;115(38):9592-9597. https://doi.org/10.1073/pnas.1803222115 
  4. Sang S, Chu C, Zhang T, Chen H, Yang X. The global burden of disease attributable to ambient fine particulate matter in 204 countries and territories, 1990-2019: a systematic analysis of the Global Burden of Disease Study 2019. Ecotoxicol Environ Saf 2022;238:113588. 
  5. Han C, Kim S, Lim YH, Bae HJ, Hong YC. Spatial and temporal trends of number of deaths attributable to ambient PM2.5 in the Korea. J Korean Med Sci 2018;33(30):e193. https://doi.org/10.3346/jkms.2018.33.e193 
  6. Orellano P, Reynoso J, Quaranta N, Bardach A, Ciapponi A. Short-term exposure to particulate matter (PM10 and PM2.5), nitrogen dioxide (NO2), and ozone (O3) and all-cause and cause-specific mortality: systematic review and meta-analysis. Environ Int 2020;142:105876. https://doi.org/10.1016/j.envint.2020.105876 
  7. Chen R, Yin P, Meng X, Liu C, Wang L, Xu X, et al. Fine particulate air pollution and daily mortality. A nationwide analysis in 272 Chinese cities. Am J Respir Crit Care Med 2017;196(1):73-81. https://doi.org/10.1164/rccm.201609-1862OC 
  8. Chen C, Zhu P, Lan L, Zhou L, Liu R, Sun Q, et al. Short-term exposures to PM2.5 and cause-specific mortality of cardiovascular health in China. Environ Res 2018;161:188-194. https://doi.org/10.1016/j.envres.2017.10.046 
  9. Li T, Guo Y, Liu Y, Wang J, Wang Q, Sun Z, et al. Estimating mortality burden attributable to short-term PM2.5 exposure: a national observational study in China. Environ Int 2019;125:245-251. https://doi.org/10.1016/j.envint.2019.01.073 
  10. Lim YH, Kim S, Han C, Bae HJ, Seo SC, Hong YC. Source country-specific burden on health due to high concentrations of PM2.5. Environ Res 2020;182:109085. https://doi.org/10.1016/j.envres.2019.109085 
  11. Burnett RT, Pope CA 3rd, Ezzati M, Olives C, Lim SS, Mehta S, et al. An integrated risk function for estimating the global burden of disease attributable to ambient fine particulate matter exposure. Environ Health Perspect 2014;122(4):397-403. https://doi.org/10.1289/ehp.1307049 
  12. Yan M, Wilson A, Bell ML, Peng RD, Sun Q, Pu W, et al. The shape of the concentration-response association between fine particulate matter pollution and human mortality in Beijing, China, and its implications for health impact assessment. Environ Health Perspect 2019;127(6):67007. https://doi.org/10.1289/EHP4464 
  13. World Health Organization. WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide; 2021 [cited 2024 Jan 2]. Available from: https://www.who.int/publications/i/item/9789240034228 
  14. Ramachandran S, Rajesh TA. Black carbon aerosol mass concentrations over Ahmedabad, an urban location in western India: comparison with urban sites in Asia, Europe, Canada, and the United States. J Geophys Res 2007;112:D06211. https://doi.org/10.1029/2006JD007488 
  15. Cheng Z, Luo L, Wang S, Wang Y, Sharma S, Shimadera H, et al. Status and characteristics of ambient PM2.5 pollution in global megacities. Environ Int 2016;89-90:212-221. https://doi.org/10.1016/j.envint.2016.02.003 
  16. Kim J, Kim SY. Comparative analysis of administrative databases for particulate matter air pollution between South Korea and the United States. J Environ Policy Adm 2020;28(1):71-100 (Korean). https://doi.org/10.15301/jepa.2020.28.1.71 
  17. Byun D, Schere KL. Review of the governing equations, computational algorithms, and other components of the Models-3 Community Multiscale Air Quality (CMAQ) modeling system. Appl Mech Rev 2006;59(2):51-77. https://doi.org/10.1115/1.2128636 
  18. Lee S, Park H, Kim S, Lee EK, Lee J, Hong YS, et al. Fine particulate matter and incidence of metabolic syndrome in non-CVD patients: a nationwide population-based cohort study. Int J Hyg Environ Health 2019;222(3):533-540. https://doi.org/10.1016/j.ijheh.2019.01.010 
  19. Almeida SP, Casimiro E, Calheiros J. Effects of apparent temperature on daily mortality in Lisbon and Oporto, Portugal. Environ Health 2010;9:12. https://doi.org/10.1186/1476-069X9-12 
  20. Alessandrini E, Zauli Sajani S, Scotto F, Miglio R, Marchesi S, Lauriola P. Emergency ambulance dispatches and apparent temperature: a time series analysis in Emilia-Romagna, Italy. Environ Res 2011;111(8):1192-1200. https://doi.org/10.1016/j.envres.2011.07.005 
  21. Guan M, Sun C, Tang D, Kang H, Chen F. A time-series analysis on the association between fine particulate matter and daily mortality - Shijiazhuang city, Hebei Province, China, 2015-2020. China CDC Wkly 2022;4(11):226-231. https://doi.org/10.46234/ccdcw2022.052 
  22. Shi Y, Xiao J, Shen Y, Yamaguchi Y. Quantifying the spatial differences of landscape change in the Hai River Basin, China, in the 1990s. Int J Remote Sens 2012;33(14):4482-4501. https://doi.org/10.1080/01431161.2011.649863 
  23. Cho ME, Kim MJ. Residents' perceptions of and response behaviors to particulate matter-a case study in Seoul, Korea. Appl Sci 2019;9(18):3660. https://doi.org/10.3390/app9183660 
  24. Baik D, Kim BW, Ki M. Increasing trends in mortality and costs of infectious diseases in Korea: trends in mortality and costs of infectious diseases. Epidemiol Health 2022;44:e2022010. https://doi.org/10.4178/epih.e2022010 
  25. Heo S, Son JY, Lim CC, Fong KC, Choi HM, Hernandez-Ramirez RU, et al. Effect modification by sex for associations of fine particulate matter (PM2.5) with cardiovascular mortality, hospitalization, and emergency room visits: systematic review and meta-analysis. Environ Res Lett 2022;17(5):053006. https://doi.org/10.1088/1748-9326/ac6cfb 
  26. Liao M, Braunstein Z, Rao X. Sex differences in particulate air pollution-related cardiovascular diseases: a review of human and animal evidence. Sci Total Environ 2023;884:163803. https://doi.org/10.1016/j.scitotenv.2023.163803 
  27. Kim HK, Lee SH. The effects of population aging on South Korea's economy: the National Transfer Accounts approach. J Econ Ageing 2021;20:100340. https://doi.org/10.1016/j.jeoa.2021.100340 
  28. Boing AF, deSouza P, Boing AC, Kim R, Subramanian SV. Air pollution, socioeconomic status, and age-specific mortality risk in the United States. JAMA Netw Open 2022;5(5):e2213540. https://doi.org/10.1001/jamanetworkopen.2022.13540 
  29. Schraufnagel DE, Balmes JR, De Matteis S, Hoffman B, Kim WJ, Perez-Padilla R, et al. Health benefits of air pollution reduction. Ann Am Thorac Soc 2019;16(12):1478-1487. https://doi.org/10.1513/AnnalsATS.201907-538CME 
  30. Qu Z, Wang X, Li F, Li Y, Chen X, Chen M. PM2.5-related health economic benefits evaluation based on air improvement action plan in Wuhan city, middle China. Int J Environ Res Public Health 2020;17(2):620. https://doi.org/10.3390/ijerph17020620 
  31. Trnka D. OECD environment working papers No. 158: policies, regulatory framework and enforcement for air quality management: the case of Korea; 2020 [cited 2024 Jan 2]. Available from: https://doi.org/10.1787/19970900 
  32. Baker D, Nieuwenhuijsen MJ. Environmental epidemiology: study methods and application. Oxford: Oxford University Press; 2008, p. 93-112. 
  33. Xi Y, Richardson DB, Kshirsagar AV, Wade TJ, Flythe JE, Whitsel EA, et al. Effects of short-term ambient PM2.5 exposure on cardiovascular disease incidence and mortality among U.S. hemodialysis patients: a retrospective cohort study. Environ Health 2022;21(1):33. https://doi.org/10.1186/s12940-022-00836-0
  34. Ward-Caviness CK, Weaver AM, Buranosky M, Pfaff ER, Neas LM, Devlin RB, et al. Associations between long-term fine particulate matter exposure and mortality in heart failure patients. J Am Heart Assoc 2020;9(6):e012517. https://doi.org/10.1161/JAHA.119.012517