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Association between Blood Mercury and Seafood Consumption in Korean Adults: KoNEHS Cycle 4 (2018~2020)

  • Ji-Eun Oh (Department of Biomedical Laboratory Science, Far East University) ;
  • Tae-Hyeong Kim (Department of Military Science, Far East University) ;
  • Eun-Hee Lee (Department of Health Science, Graduate School of Far East University)
  • Received : 2024.02.19
  • Accepted : 2024.03.11
  • Published : 2024.03.31

Abstract

Mercury is a chemical pollutant widely present in the environment. Humans are generally exposed to mercury in the form of organic Hg (methylmercury) through the consumption of seafood. Koreans enjoy eating fish therefore blood mercury concentration is usually higher than in developed countries. By investigating blood mercury concentration according to the frequency of seafood consumption and sociodemographic factors, we aimed to identify recent trends in blood mercury concentration in Korean adults. This study was conducted using KoNEHS cycle 4 (2018~2020) from the National Institute Environmental Research Survey. The geometric mean concentration of blood mercury of the subjects was 2.959 (±1.018) ㎍/L, which was significantly higher in men than in women. It was observed that as the frequency of fish and shellfish consumption increased, the blood mercury concentration increased. In adjusted logistic regression, fish consumption was associated with 36.7% increased risk of blood mercury levels [Odds ratio, 1.367; 95% confidence interval (CI), 1.246~1.500], and shellfish consumption was associated with 26.5% increased risk of blood mercury levels [Odds ratio, 1.265; 95% confidence interval (CI), 1.134~1.410]. Blood mercury concentration was also found to increase as the socioeconomic level increased. In conclusion, the geometric mean concentration of blood mercury was increased compared to the one in the 3rd KoNEHS (2015~2017) and seafood consumption and socioeconomic level were still significantly associated with increasing blood mercury concentration in Korea. Therefore, it is necessary to encourage healthy seafood consumption habits and conduct continuous monitoring considering various factors to reduce blood mercury levels.

Keywords

Acknowledgement

This study used the Korean National Environmental Health Survey Cycle 4 (2018~2020) data, made by National Institute of Environmental Research (NIER-2018-01-01-001).

References

  1. Al-Sulaiti MM, Soubra L, Al-Ghouti MA. The Causes and Effects of Mercury and Methylmercury Contamination in the Marine Environment: A Review. Curr Pollution Rep. 2022. 8: 249-272. https://doi.org/10.1007/s40726-022-00226-7
  2. Amezcua F, Ruelas-Inzunza J, Coiraton C, Spanopoulos-Zarco P, Paez-Osuna F. A Global Review of Cadmium, Mercury, and Selenium in Sharks: Geographical Patterns, Baseline Levels and Human Health Implications. Reviews Env Contamination (formerly: Residue Reviews). 2022. 260: 4.
  3. Baek K, Park C, Sakong J. Increase of blood mercury level with shark meat consumption: A repeated-measures study before and after Chuseok, Korean holiday. Chemosphere. 2023. 344: 140317-140326.
  4. Basu N, Bastiansz A, Dorea JG, Fujimura M, Horvat M, Shroff E, Weihe P, Zastenskaya I. Our evolved understanding of the human health risks of mercury. Ambio. 2023. 52: 877-896. https://doi.org/10.1007/s13280-023-01831-6
  5. Basu N, Horvat M, Evers DC, Zastenskaya I, Weihe P, Tempowski J. A State-of-the-Science Review of Mercury Biomarkers in Human Populations Worldwide between 2000 and 2018. Environ Health Perspect. 2018. 126: 106001-106014. https://doi.org/10.1289/EHP3904
  6. Bene C, Barange M, Subasinghe R, Pinstrup-Andersen P, Merino G, Hemre GI, Williams M. Feeding 9 billion by 2050 - Putting fish back on the menu. Food Sec. 2015. 7: 261-274. https://doi.org/10.1007/s12571-015-0427-z
  7. Chen B, Dong S. Mercury Contamination in Fish and Its Effects on the Health of Pregnant Women and Their Fetuses, and Guidance for Fish Consumption-A Narrative Review. Int J Environ Res Public Health. 2022. 19: 15929-15946. https://doi.org/10.3390/ijerph192315929
  8. Choi H, Park SK, Kim MH. Risk Assessment of Mercury through Food Intake for Korean Population. Korean J Food Sci Technol. 2012. 44: 106-113. https://doi.org/10.9721/KJFST.2012.44.1.106
  9. Clarkson TW, Magos L. The toxicology of mercury and its chemical compounds. Crit Rev Toxicol. 2006. 36: 609-662. https://doi.org/10.1080/10408440600845619
  10. Groth E 3rd. Ranking the contributions of commercial fish and shellfish varieties to mercury exposure in the United States: implications for risk communication. Environ Res. 2010. 110:226-236. https://doi.org/10.1016/j.envres.2009.12.006
  11. Hightower JM, Moore D. Mercury levels in high-end consumers of fish. Environ Health Perspect. 2003. 111: 604-608. https://doi.org/10.1289/ehp.5837
  12. Kang SH, Lee MJ, Kim JK, Jung YJ, Hur ES, Cho YS, Moh A, Park KH. Contents of total mercury and methylmercury in deep-sea fish, tuna, billfish and fishery products. J Food Hyg Saf. 2017. 32: 42-49.
  13. Kim CW, Kim YW, Chae CH, Son JS, Kim JH, Park HO, Kang YS, Kim JR, Hong YS, Kim DS, Jeong BG. The Relationship between Fish Consumption and Blood Mercury Levels in Residents of Busan Metropolitan City and Gyeongnam Province. J Agric Med Community Health. 2012. 37: 223-232. https://doi.org/10.5393/JAMCH.2012.37.4.223
  14. Kim JH, Cho YT. Convergent association between socioeconomic status and the blood concentrations of mercury, lead, and cadmium in the Korean adult population: based on the sixth Korea National Health and Nutritional Examination Surveys (KNHANES 2013-2015). J Korea Conv Soc. 2019. 10: 51-61.
  15. Kim NY. Blood Mercury Concentration by the Frequency of Fish and Shellfish Consumption in Korean Adults. Jeju National University. 2020.
  16. Kim SM. A Study on the EU's Legislative Proposal for a Regulation on Mercury for the Implementation of the Minamata Convention. 2017. 17: 1-23.
  17. Mahaffey KR, Clickner RP, Jeffries RA. Adult women's blood mercury concentrations vary regionally in the United States: association with patterns of fish consumption (NHANES 1999-2004). Environ Health Perspect. 2009. 117: 47-53. https://doi.org/10.1289/ehp.11674
  18. Morrens B, Bruckers L, Hond ED, Nelen V, Schoeters G, Baeyens W, Van Larebeke N, Keune H, Bilau M, Loots I. Social distribution of internal exposure to environmental pollution in Flemish adolescents. Int J Hyg Environ Health. 2012. 215: 474-481. https://doi.org/10.1016/j.ijheh.2011.10.008
  19. Park GI, Byun YS, Joong Jeon M, Sakong J. The associations between blood mercury levels and shark meat intake among workers in Gyeongsangbuk-do. Ann of Occup and Environ Med. 2017. 29: 29-35. https://doi.org/10.1186/s40557-017-0185-9
  20. Sakong J. Health Effects of Mercury Exposure through Fish. Yeungnam Univ J Med. 2011. 28: 105-115. https://doi.org/10.12701/yujm.2011.28.2.105
  21. Seo JW, Kim BG, Kim YM, Kim RB, Chung JY, Lee KM, Hong YS. Trend of blood lead, mercury, and cadmium levels in Korean population: data analysis of the Korea National Health and Nutrition Examination Survey. Environ Monit Assess. 2015. 7: 146-158.
  22. Sheehan MC, Burke TA, Navas-Acien A, Breysse PN, McGready J, Fox MA. Global methylmercury exposure from seafood consumption and risk of developmental neurotoxicity: a systematic review. Bull World Health Organ. 2014. 92: 254-269F.
  23. Sioen I, De Henauw S, Van Camp J, Volatier JL, Leblanc JC. Comparison of the nutritional-toxicological conflict related to seafood consumption in different regions worldwide. Regul Toxicol Pharmacol. 2009. 55: 219-228.
  24. Tyrrell J, Melzer D, Henley W, Galloway TS, Osborne NJ. Associations between socioeconomic status and environmental toxicant concentrations in adults in the USA: NHANES 2001~2010. Environ Int. 2013. 59: 328-335. https://doi.org/10.1016/j.envint.2013.06.017
  25. Vrijheid M, Martinez D, Aguilera I, Ballester F, Basterrechea M, Esplugues A, Guxens M, Larrangaga M, Lertxundi A, Mendez M, Murcia M, Marina LS, Villanueva CM, Sunyer J. Socioeconomic status and exposure to multiple environmental pollutants during pregnancy: evidence for environmental inequity? J Epidemiol Community Health. 2012. 66: 106-113. https://doi.org/10.1136/jech.2010.117408
  26. Yorifuji T, Tsuda T, Inoue S, Takao S, Harada M. Long-term exposure to methylmercury and psychiatric symptoms in residents of Minamata, Japan. Environ Int. 2011. 37: 907-913. https://doi.org/10.1016/j.envint.2011.03.008