The Plant Pathology Journal

한국식물병리학회 (The Korean Society of Plant Pathology)
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Antifungal Activity-Guided Analysis of Actinostemma lobatum Extracts through Serial Sub-fractions

  • Seonwoo Choi (Department of Biotechnology, College of Life and Applied Sciences, Yeungnam University) ;
  • Song Hee Lee (Plant Immunity Research Center, Seoul National University) ;
  • Byeong Su Hwang (Animal and Plant Research Department, Nakdonggang National Institute of Biological Resources) ;
  • Young Taek Oh (Animal and Plant Research Department, Nakdonggang National Institute of Biological Resources) ;
  • Junhyun Jeon (Department of Biotechnology, College of Life and Applied Sciences, Yeungnam University)
  • 투고 : 2023.11.12
  • 심사 : 2024.03.06
  • 발행 : 2024.04.01
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초록

Plants are treasure trove of novel compounds that have potential for antifungal chemicals and drugs. In our previous study, we had screened plant extracts obtained from more than eight hundred plant materials collected in Korea, and found that butanol fraction of the Actinostemma lobatum were most potent in suppressing growth of diverse fungal pathogens of plants. Here in this study, we describe further analysis of the butanol fraction, and summarize the results of subsequent antifungal activity test for the sub-fractions against a selected set of plant pathogenic fungi. This line of analyses allowed us to identify the sub-fractions that could account for a significant proportion of observed antifungal activity of initial butanol fraction from A. lobatum. Further analysis of these sub-fractions and determination of structure would provide the shortlist for novel compounds that can be a lead to new agrochemicals.

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과제정보

This work was supported by a grant from the Nakdonggang National Institute of Biological Resources (NNIBR), funded by the Ministry of Environment (MOE) of the Republic of Korea (NNIBR202102101).

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