DOI QR코드

DOI QR Code

A Case Study on Improving Hair Loss Using Ortho-cellular Nutrition Therapy (OCNT)

세포교정영양요법(OCNT)을 이용한 탈모 개선 사례

  • Received : 2024.03.29
  • Accepted : 2024.03.29
  • Published : 2024.03.29

Abstract

Objective: Case report on hair loss improvement by ortho-cellular nutrition therapy. Methods: A Korean woman in her 60s suffers from hair loss. Results: Hair loss was significantly improved after OCNT. Conclusion: OCNT may help alleviate hair loss symptoms.

Keywords

References

  1. Ho, C.-Y. et al. Female Pattern Hair Loss: An Overview with Focus on the Genetics. Genes 14, 1326 (2023).
  2. Rushton, D., Norris, M., Dover, R. & Busuttil, N. Causes of hair loss and the developments in hair rejuvenation. International journal of cosmetic science 24, 17-23 (2002).
  3. Sadick, N. & Arruda, S. Understanding causes of hair loss in women. Dermatologic clinics 39, 371-374 (2021). https://doi.org/10.1016/j.det.2021.03.002
  4. Ohn, J. et al. Early onset female pattern hair loss: A case-control study for analyzing clinical features and genetic variants. Journal of Dermatological Science 106, 21-28 (2022). https://doi.org/10.1016/j.jdermsci.2022.02.011
  5. Mirmirani, P. Hormonal changes in menopause: do they contribute to a 'midlife hair crisis' in women? British Journal of Dermatology 165, 7-11 (2011). https://doi.org/10.1111/j.1365-2133.2011.10629.x
  6. Finner, A. M. Nutrition and hair: deficiencies and supplements. Dermatologic clinics 31, 167-172 (2013). https://doi.org/10.1016/j.det.2012.08.015
  7. Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P. & Tosti, A. The role of vitamins and minerals in hair loss: a review. Dermatology and therapy 9, 51-70 (2019). https://doi.org/10.1007/s13555-018-0278-6
  8. Pearson, L. K. Adiponectin in equine reproduction, Washington State University, (2015).
  9. Ohn, J. et al. Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth. EMBO Molecular Medicine 13, e13790 (2021).
  10. Tosti, A. & Schwartz, J. R. Role of scalp health in achieving optimal hair growth and retention. International journal of cosmetic science 43, S1-S8 (2021).
  11. Darvin, M. E. et al. Influence of the systemic application of blue-green Spirulina platensis algae on the cutaneous carotenoids and elastic fibers in vivo. Cosmetics 2, 302-312 (2015). https://doi.org/10.3390/cosmetics2030302
  12. Horii, Y., Mizoguchi, T., Fujisaki, Y., Fuyuki, R. & Nagai, K. Effects of Chlorella pyrenoidosa on cutaneous arterial sympathetic nerve activity, cutaneous blood flow and transepidermal water loss in rats. Current Topics in Nutraceutical Research 12 (2014).
  13. Adelman, M. J., Bedford, L. M. & Potts, G. A. Clinical efficacy of popular oral hair growth supplement ingredients. International Journal of Dermatology 60, 1199-1210 (2021).
  14. Benjamin, R. Methylsulfonylmethane and Hair Health.
  15. Shanmugam, S. et al. The effect of methylsulfonylmethane on hair growth promotion of magnesium ascorbyl phosphate for the treatment of alopecia. Biomolecules & Therapeutics 17, 241-248 (2009). https://doi.org/10.4062/biomolther.2009.17.3.241
  16. Karashima, T. et al. Oral zinc therapy for zinc deficiency-related telogen effluvium. Dermatologic Therapy 25, 210-213 (2012).
  17. Miniaci, M. C. et al. Cysteine prevents the reduction in keratin synthesis induced by iron deficiency in human keratinocytes. Journal of cellular biochemistry 117, 402-412 (2016).
  18. Hu, X. et al. Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis. European Journal of Pharmacology 963, 176237 (2024).
  19. 문인석. Fucoidan promotes mechanosensory hair cell regeneration following aminoglycoside induced cell damage, Graduate School, Yonsei University, (2011).
  20. Bayer, M., Gahrtz, M., Voss, W., Schlippe, G. & Whitfield, T. The effect of a food supplement and a hair lotion on the progression of androgenetic alopecia. Journal of Cosmetics, Dermatological Sciences and Applications 9, 292-304 (2019). https://doi.org/10.4236/jcdsa.2019.94026
  21. Edgar, S. et al. Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts. Scientific Reports 8, 10474 (2018).
  22. Park, Y. et al. Sulforaphane, L-Menthol, and Dexpanthenol as a Novel Active Cosmetic Ingredient Composition for Relieving Hair Loss Symptoms. Cosmetics 8, 63 (2021).
  23. Kim, H.-T. et al. Double-blind randomized placebo-controlled study of the efficacy and safety of hair loss prevention shampoo containing salicylic acid, panthenol, and niacinamide in alopecia patients. Toxicology and Environmental Health Sciences 14, 173-185 (2022). https://doi.org/10.1007/s13530-022-00126-9
  24. Zerbinati, N. et al. In Vitro Hair Growth Promoting Effect of a Noncrosslinked Hyaluronic Acid in Human Dermal Papilla Cells. BioMed Research International 2021, 5598110 (2021).
  25. Choi, Y. M. et al. Titrated extract of Centella asiatica increases hair inductive property through inhibition of STAT signaling pathway in three-dimensional spheroid cultured human dermal papilla cells. Bioscience, biotechnology, and biochemistry 81, 2323-2329 (2017). https://doi.org/10.1080/09168451.2017.1385383
  26. Le Floc'h, C. et al. Effect of a nutritional supplement on hair loss in women. Journal of cosmetic dermatology 14, 76-82 (2015).
  27. Al-Niaimi, F. & Chiang, N. Y. Z. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol 10, 14-17 (2017).
  28. Xiong, Z. et al. An overview of the bioactivity of monacolin K / lovastatin. Food and Chemical Toxicology 131, 110585 (2019).
  29. Zhang, Y. et al. An overview on the biosynthesis and metabolic regulation of monacolin K/lovastatin. Food & function 11, 5738-5748 (2020). https://doi.org/10.1039/D0FO00691B