Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Penile neoplasm associated with Equus caballus papillomavirus type 2 infection in a miniature Appaloosa: a case report

  • Sang-Kyu Lee (Veterinary Center, Korea Racing Authority) ;
  • Jungho Yoon (Equine Referral Clinic, Jeju Stud Farm, Korea Racing Authority) ;
  • Youngjong Kim (Equine Hospital, Jeju Racecourse Park, Korea Racing Authority) ;
  • Inhyung Lee (Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Seoul National University)
  • Received : 2024.02.27
  • Accepted : 2024.03.21
  • Published : 2024.03.31
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Abstract

An 18-year-old miniature Appaloosa stallion presented with 6 months of history of sanguineous crusts on medial hind limbs and discomfort of micturition. Cauliflower-like and small masses were treated with cryotherapy for 6 months, but the regrowth of masses occurred. Subsequently, local excision via laser and topical treatment with 5% 5-fluorouracil for 5 months were followed. However, the horse was euthanized 4 months later due to regrowth of the masses. The mass was diagnosed as penile papilloma with cellular atypia and Equus caballus papillomavirus type 2 (EcPV-2) DNA was detected. This is the first report of equine penile neoplasm with EcPV-2 infection in Asia.

Keywords

Acknowledgement

The authors appreciate to Dr. Jung-Keun Lee for the expert advice on histopathology. The authors also thank veterinary staffs of Korea Racing Authority for the assistance and support.

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