DOI QR코드

DOI QR Code

Prevalence of posttraumatic stress disorder in orthopedic trauma patients and a call to implement the Injured Trauma Survivor Screen as a prospective screening protocol in the United States

  • Victoria J. Nedder (Department of Orthopedic Surgery, Case Western Reserve University School of Medicine) ;
  • Mary A. Breslin (Department of Orthopedic Surgery, Case Western Reserve University School of Medicine) ;
  • Vanessa P. Ho (Department of Orthopedic Surgery, Case Western Reserve University School of Medicine) ;
  • Heather A. Vallier (Department of Orthopedic Surgery, Case Western Reserve University School of Medicine)
  • 투고 : 2023.09.23
  • 심사 : 2023.11.10
  • 발행 : 2024.03.31

초록

Purpose: Posttraumatic stress disorder (PTSD) is prevalent and is associated with protracted recovery and worse outcomes after injury. This study compared PTSD prevalence using the PTSD Checklist for DSM-5 (PCL-5) with the prevalence of PTSD risk using the Injured Trauma Survivor Screen (ITSS). Methods: Adult trauma patients at a level I trauma center were screened with the PCL-5 (sample 1) at follow-up visits or using the ITSS as inpatients (sample 2). Results: Sample 1 (n=285) had significantly fewer patients with gunshot wounds than sample 2 (n=45) (8.1% vs. 22.2%, P=0.003), nonsignificantly fewer patients with a fall from a height (17.2% vs. 28.9%, P=0.06), and similar numbers of patients with motor vehicle collision (40.7% vs. 37.8%, P=0.07). Screening was performed at a mean of 154 days following injury for sample 1 versus 7.1 days in sample 2. The mean age of the patients in sample 1 was 45.4 years, and the mean age of those in sample 2 was 46.1 years. The two samples had similar proportions of female patients (38.2% vs. 40.0%, P=0.80). The positive screening rate was 18.9% in sample 1 and 40.0% in sample 2 (P=0.001). For specific mechanisms, the positive rates were as follows: motor vehicle collisions, 17.2% in sample 1 and 17.6% in sample 2 (P>0.999); fall from height, 12.2% in sample 1 and 30.8% in sample 2 (P=0.20); and gunshot wounds, 39.1% in sample 1 and 80.0% in sample 2 (P=0.06). Conclusions: The ITSS was obtained earlier than PCL-5 and may identify PTSD in more orthopedic trauma patients. Differences in the frequency of PTSD may also be related to the screening tool itself, or underlying patient risk factors, such as mechanism of injury, or mental or social health.

키워드

과제정보

Vanessa P. Ho is supported by the Clinical and Translational Science Collaborative (CTSC) of Cleveland (No. KL2TR002547 from the National Center for Advancing Translational Sciences [NCATS] component of the US National Institutes of Health and NIH Roadmap for Medical Research).

참고문헌

  1. Joseph NM, Benedick A, Flanagan CD, et al. Prevalence of posttraumatic stress disorder in acute trauma patients. OTA Int 2020;3:e056.
  2. Aaron DL, Fadale PD, Harrington CJ, Born CT. Posttraumatic stress disorders in civilian orthopaedics. J Am Acad Orthop Surg 2011;19:245-50. https://doi.org/10.5435/00124635-201105000-00001
  3. Muscatelli S, Spurr H, O'Hara NN, O'Hara LM, Sprague SA, Slobogean GP. Prevalence of depression and posttraumatic stress disorder after acute orthopaedic trauma: a systematic review and meta-analysis. J Orthop Trauma 2017;31:47-55.
  4. Ponsford J, Hill B, Karamitsios M, Bahar-Fuchs A. Factors influencing outcome after orthopedic trauma. J Trauma 2008;64:1001-9.
  5. Williams AE, Newman JT, Ozer K, Juarros A, Morgan SJ, Smith WR. Posttraumatic stress disorder and depression negatively impact general health status after hand injury. J Hand Surg Am 2009;34:515-22.
  6. Helmerhorst GT, Vranceanu AM, Vrahas M, Smith M, Ring D. Risk factors for continued opioid use one to two months after surgery for musculoskeletal trauma. J Bone Joint Surg Am 2014;96:495-9. https://doi.org/10.2106/JBJS.L.01406
  7. Simske NM, Audet MA, Kim CY, Benedick A, Vallier HA. Mental illness is associated with more pain and worse functional outcomes after ankle fracture. OTA Int 2019;2:e037.
  8. Davis LL, Schein J, Cloutier M, et al. The economic burden of posttraumatic stress disorder in the United States from a societal perspective. J Clin Psychiatry 2022;83:21m14116.
  9. Flanagan CD, Rascoe AS, Wang DM, Vallier HA. Revenue for initial orthopaedic trauma care: effects of patient and injury characteristics. J Orthop Trauma 2018;32:433-8. https://doi.org/10.1097/BOT.0000000000001192
  10. Vranceanu AM, Beks RB, Guitton TG, Janssen SJ, Ring D. How do orthopaedic surgeons address psychological aspects of illness? Arch Bone Jt Surg 2017;5:2-9.
  11. US National Institute of Mental Health (NIMH). Post-traumatic stress disorder [Internet]. NIMH; 2023 [cited 2023 Apr 25]. Available from: https://www.nimh.nih.gov/health/topics/post-traumatic-stress-disorder-ptsd
  12. Hunt JC, Sapp M, Walker C, Warren AM, Brasel K, deRoon-Cassini TA. Utility of the injured trauma survivor screen to predict PTSD and depression during hospital admission. J Trauma Acute Care Surg 2017;82:93-101. https://doi.org/10.1097/TA.0000000000001306
  13. Hunt JC, Chesney SA, Brasel K, deRoon-Cassini TA. Sixmonth follow-up of the injured trauma survivor screen: clinical implications and future directions. J Trauma Acute Care Surg 2018;85:263-70. https://doi.org/10.1097/TA.0000000000001944
  14. National Center for PTSD. PTSD Checklist for DSM-5 (PCL-5) [Internet]. US Department of Veterans Affairs; [cited 2023 Apr 25]. Available from: https://www.ptsd.va.gov/professional/assessment/adult-sr/ptsd-checklist.asp
  15. National Center for Education Statistics. Fast facts [Internet]. US Department of Education; [cited 2023 Apr 25]. Available from: https://nces.ed.gov/fastfacts/display.asp?id=69
  16. Rothbaum BO, Kearns MC, Price M, et al. Early intervention may prevent the development of posttraumatic stress disorder: a randomized pilot civilian study with modified prolonged exposure. Biol Psychiatry 2012;72:957-63. https://doi.org/10.1016/j.biopsych.2012.06.002
  17. Maples-Keller JL, Post LM, Price M, et al. Investigation of optimal dose of early intervention to prevent posttraumatic stress disorder: a multiarm randomized trial of one and three sessions of modified prolonged exposure. Depress Anxiety 2020;37:429-37. https://doi.org/10.1002/da.23015
  18. Rothbaum BO, Kearns MC, Reiser E, et al. Early intervention following trauma may mitigate genetic risk for PTSD in civilians: a pilot prospective emergency department study. J Clin Psychiatry 2014;75:1380-7.
  19. American College of Surgeons. Resources for optimal care of the injured patient [Internet]. American College of Surgeons; 2023 [cited 2023 Apr 25]. Available from: https://www.facs.org/quality-programs/trauma/quality/verification-review-and-consultation-program/standards/
  20. American Psychiatric Association (APA). Diagnostic and statistical manual of mental disorders: DSM-5. 5th ed. APA; 2013.
  21. Galatzer-Levy IR, Bryant RA. 636,120 Ways to have posttraumatic stress disorder. Perspect Psychol Sci 2013;8:651-62. https://doi.org/10.1177/1745691613504115
  22. Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1995;52:1048-60. https://doi.org/10.1001/archpsyc.1995.03950240066012
  23. Schein J, Houle C, Urganus A, et al. Prevalence of post-traumatic stress disorder in the United States: a systematic literature review. Curr Med Res Opin 2021;37:2151-61. https://doi.org/10.1080/03007995.2021.1978417
  24. Gillespie CF, Bradley B, Mercer K, et al. Trauma exposure and stress-related disorders in inner city primary care patients. Gen Hosp Psychiatry 2009;31:505-14. https://doi.org/10.1016/j.genhosppsych.2009.05.003
  25. Rothbaum BO, Foa EB, Riggs DS, Murdock T, Walsh W. A prospective examination of post-traumatic stress disorder in rape victims. J Trauma Stress 1992;5:455-75.
  26. Hinrichs R, Michopoulos V, Winters S, et al. Mobile assessment of heightened skin conductance in posttraumatic stress disorder. Depress Anxiety 2017;34:502-7. https://doi.org/10.1002/da.22610
  27. Hinrichs R, van Rooij SJ, Michopoulos V, et al. Increased skin conductance response in the immediate aftermath of trauma predicts PTSD risk. Chronic Stress (Thousand Oaks) 2019;3:2470547019844441.