과제정보
This research was supported by the Bio & Medical Technology Development Program (grant number: NRF-2017M3A9A7050614, NRF-2017M3A9A7050610 and NRF-2023M3A9A7009442) and the Korea BioData Station Program.
참고문헌
- Das PM and Singal R (2004) DNA methylation and cancer. J Clin Oncol 22, 4632-4642 https://doi.org/10.1200/JCO.2004.07.151
- Lakshminarasimhan R and Liang G (2016) The role of DNA methylation in cancer. Adv Exp Med Biol 945, 151-172 https://doi.org/10.1007/978-3-319-43624-1_7
- Nishiyama A and Nakanishi M (2021) Navigating the DNA methylation landscape of cancer. Trends Genet 37, 1012-1027 https://doi.org/10.1016/j.tig.2021.05.002
- Herman JG, Umar A, Polyak K et al (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 95, 6870-6875 https://doi.org/10.1073/pnas.95.12.6870
- Zhao P, Li L, Jiang X and Li Q (2019) Mismatch repair deficiency/microsatellite instability-high as a predictor for anti-PD-1/PD-L1 immunotherapy efficacy. J Hematol Oncol 12, 54
- Zlobec I, Bihl M, Foerster A, Rufle A and Lugli A (2011) Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features. J Pathol 225, 336-343 https://doi.org/10.1002/path.2879
- Nazemalhosseini Mojarad E, Kuppen PJ, Aghdaei HA and Zali MR (2013) The CpG island methylator phenotype (CIMP) in colorectal cancer. Gastroenterol Hepatol Bed Bench 6, 120-128
- Guinney J, Dienstmann R, Wang X et al (2015) The consensus molecular subtypes of colorectal cancer. Nat Med 21, 1350-1356 https://doi.org/10.1038/nm.3967
- Singh MP, Rai S, Pandey A, Singh NK and Srivastava S (2021) Molecular subtypes of colorectal cancer: an emerging therapeutic opportunity for personalized medicine. Genes Dis 8, 133-145 https://doi.org/10.1016/j.gendis.2019.10.013
- Joe S, Kim J, Lee JY et al (2023) Epigenetic insights into colorectal cancer: comprehensive genome-wide DNA methylation profiling of 294 patients in Korea. BMB Rep 56, 563-568 https://doi.org/10.5483/BMBRep.2023-0096
- Galanter JM, Gignoux CR, Oh SS et al (2017) Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures. eLife 6, e20532
- Jeon SA, Ha YJ, Kim JH et al (2022) Genomic and transcriptomic analysis of Korean colorectal cancer patients. Genes Genomics 44, 967-979 https://doi.org/10.1007/s13258-022-01275-4
- Lee SH, Lee B, Shim JH et al (2019) Landscape of actionable genetic alterations profiled from 1,071 tumor samples in Korean cancer patients. Cancer Res Treat 51, 211-222 https://doi.org/10.4143/crt.2018.132
- Yang X, Han H, De Carvalho DD, Lay FD, Jones PA and Liang G (2014) Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 26, 577-590 https://doi.org/10.1016/j.ccr.2014.07.028
- McInnes T, Zou D, Rao DS et al (2017) Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. BMC Cancer 17, 228
- Silva AL, Dawson SN, Arends MJ et al (2014) Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists. BMC Cancer 14, 891
- Guo X and Wang XF (2009) Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res 19, 71-88 https://doi.org/10.1038/cr.2008.302
- Huang F and Chen YG (2012) Regulation of TGF-beta receptor activity. Cell Biosci 2, 9
- Ding N, Luo H, Zhang T, Peng T, Yao Y and He Y (2023) Correlation between SMADs and colorectal cancer expression, prognosis, and immune infiltrates. Int J Anal Chem 2023, 8414040
- Hata A and Chen YG (2016) TGF-beta signaling from receptors to Smads. Cold Spring Harb Perspect Biol 8, a022061
- Wagstaff L, Kelwick R, Decock J and Edwards DR (2011) The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis. Front Biosci (Landmark Ed) 16, 1861-1872 https://doi.org/10.2741/3827
- Choi JE, Kim DS, Kim EJ et al (2008) Aberrant methylation of ADAMTS1 in non-small cell lung cancer. Cancer Genet Cytogenet 187, 80-84 https://doi.org/10.1016/j.cancergencyto.2008.08.001
- Lind GE, Kleivi K, Meling GI et al (2006) ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis. Cell Oncol 28, 259-272 https://doi.org/10.1155/2006/949506
- Cal S and Lopez-Otin C (2015) ADAMTS proteases and cancer. Matrix Biol 44-46, 77-85 https://doi.org/10.1016/j.matbio.2015.01.013
- Hibi K, Kodera Y, Ito K, Akiyama S and Nakao A (2004) Methylation pattern of CDH13 gene in digestive tract cancers. Br J Cancer 91, 1139-1142 https://doi.org/10.1038/sj.bjc.6602095
- Yan H, He J, Guan Q et al (2017) Identifying CpG sites with different differential methylation frequencies in colorectal cancer tissues based on individualized differential methylation analysis. Oncotarget 8, 47356-47364 https://doi.org/10.18632/oncotarget.17647
- Zhang Y, Yang J, Wang X and Li X (2021) GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses. Sci Rep 11, 20441
- Fan Y, Mu J, Huang M et al (2019) Epigenetic identification of ADCY4 as a biomarker for breast cancer: an integrated analysis of adenylate cyclases. Epigenomics 11, 1561-1579 https://doi.org/10.2217/epi-2019-0207
- Jass JR (2007) Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 50, 113-130 https://doi.org/10.1111/j.1365-2559.2006.02549.x
- Sugai T, Habano W, Jiao YF et al (2006) Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: proposal for new molecular profile of colorectal carcinomas. J Mol Diagn 8, 193-201 https://doi.org/10.2353/jmoldx.2006.050052
- Petrelli F, Tomasello G, Borgonovo K et al (2017) Prognostic survival associated with left-sided vs right-sided colon cancer: a systematic review and meta-analysis. JAMA Oncol 3, 211-219 https://doi.org/10.1001/jamaoncol.2016.4227
- Lee B, Hwang S, Kim PG et al (2023) Introduction of the Korea BioData Station (K-BDS) for sharing biological data. Genomics Inform 21, e12