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Atypical Fibroma and Fibrosarcoma Derived from Cutaneous Ganglion Cell-Like Cells in Ten Djungarian Hamsters (Phodopus sungorus)

  • Ji-Youl Jung (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Han-Na Kim (Hana Animal Hospital) ;
  • Da-Ye Nam (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • So-Jeong Yim (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jae-Hoon Kim (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 투고 : 2023.12.06
  • 심사 : 2024.01.31
  • 발행 : 2024.02.28

초록

Ten cutaneous masses from Djungarina hamsters (Phodopus sungorus) were diagnosed as nine atypical fibromas and one fibrosarcoma derived from cutaneous ganglion cell-like cells. Among these patients, nine were male and one was female. Histologically, these abnormal masses were composed of spindle-shaped or polygonal neoplastic 'ganglion cell-like' cells with abundant amphophilic vacuolated cytoplasm. Immunohistochemically, these neoplastic cells were stained for vimentin, S100, and neuron-specific enolase. Out of 9 males, 3 showed positive reactions to the androgen receptor. This report provides a detailed histologic and immunohistochemical characterization of atypical fibroma, fibrosarcoma, and the tumorigenesis of ganglion cell-like cells in Djungarian hamsters.

키워드

과제정보

This research was supported by the 2023 Scientific Promotion Program funded by Jeju National University.

참고문헌

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