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Transdermal scopolamine for the treatment of recurrent parotid sialocele: a case report

  • Chi Hyun Lee (Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine) ;
  • Changryul Claud Yi (Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine) ;
  • Yong Chan Bae (Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine) ;
  • Jae Woo Lee (Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine) ;
  • Byung-Joo Lee (Biomedical Research Institute, Pusan National University Hospital) ;
  • Joo Hyoung Kim (Department of Plastic and Reconstructive Surgery, Pusan National University School of Medicine)
  • Received : 2023.07.13
  • Accepted : 2023.12.27
  • Published : 2024.02.20

Abstract

Recurrent parotid sialocele is rare and challenging to treat. Treatment options are limited for cases of parotid sialocele that recur despite ductal ligation. This case study presents a patient who underwent wide excision of the right buccal mucosa due to squamous cell carcinoma. During the wide excision, a segment of the parotid duct was excised, and ductal ligation was performed to prevent the occurrence of a sialocele, followed by reconstruction using a folded anterolateral thigh free flap. Twenty-two days after surgery, parotid sialocele occurred despite the initial ductal ligation and subsequent ductal ligation was performed; however, the sialocele recurred. As an alternative therapeutic option, a transdermal scopolamine patch was applied for 3 weeks, with one patch used every 3 days. The results were encouraging, with complete resolution of the sialocele. A transdermal scopolamine offers a noninvasive, convenient method of treating parotid sialocele with minimal side effects. The successful outcome of this case suggests that a transdermal scopolamine can be an effective therapeutic option for recurrent parotid sialocele in conjunction with surgical treatment.

Keywords

Acknowledgement

This work was supported by a 2-Year Research Grant of Pusan National University.

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