DOI QR코드

DOI QR Code

A Case Study on the Improvement of Multiple Alopecia Areata using Ortho-Cellular Nutrition Therapy (OCNT)

세포교정영양요법(OCNT)을 이용한 다발성 원형 탈모 개선 사례 연구

  • Received : 2023.11.30
  • Accepted : 2023.11.30
  • Published : 2023.11.30

Abstract

Objective: Report on the case of improvement of multiple alopecia areata through implementation of Ortho-Cellular Nutrition Therapy (OCNT). Methods: A Korean female in her 50s suffering from multiple alopecia areata. Results: Multiple alopecia areata was improved following implementation of OCNT. Conclusion: Application of OCNT can be helpful to multiple alopecia areata.

Keywords

References

  1. Scott, S. B. et al. The effects of stress on cognitive aging, physiology and emotion (ESCAPE) project. BMC psychiatry 15, 1-14 (2015).  https://doi.org/10.1186/s12888-014-0378-5
  2. Tobin, D. J., Orentreich, N., Fenton, D. A. & Bystryn, J. C. Antibodies to hair follicles in alopecia areata. J Invest Dermatol 102, 721-724 (1994).  https://doi.org/10.1111/1523-1747.ep12375477
  3. Ziegler, M. G. in Primer on the Autonomic Nervous System (Third Edition) (eds David Robertson et al.) 291-293 (Academic Press, 2012). 
  4. Khansari, D. N., Murgo, A. J. & Faith, R. E. Effects of stress on the immune system. Immunology Today 11, 170-175 (1990).  https://doi.org/10.1016/0167-5699(90)90069-L
  5. Stojanovich, L. & Marisavljevich, D. Stress as a trigger of autoimmune disease. Autoimmunity Reviews 7, 209-213 (2008).  https://doi.org/10.1016/j.autrev.2007.11.007
  6. Vinay, K., Sawatkar, G. U. & Dogra, S. Hair manifestations of endocrine diseases: A brief review. Indian Journal of Dermatology, Venereology and Leprology 84, 528 (2018). 
  7. Rajabi, F., Drake, L., Senna, M. & Rezaei, N. Alopecia areata: a review of disease pathogenesis. British Journal of Dermatology 179, 1033-1048 (2018).  https://doi.org/10.1111/bjd.16808
  8. Abdel-Daim, M. M. et al. Fucoidan supplementation modulates hepatorenal oxidative stress and DNA damage induced by aflatoxin B1 intoxication in rats. Science of the Total Environment 768, 144781 (2021). 
  9. Dae-Hong Min & Nagan. Fucoidan-based nanoionic complexes for enhancement of the antioxidant activity of anthocyanins. Journal of Biomaterials 16, 60-66 (2012). 
  10. Han, N. R. et al. The immune-enhancing effect of anthocyanin-fucoidan nanocomplex in RAW264. 7 macrophages and cyclophosphamide-induced immunosuppressed mice. Journal of Food Biochemistry 45, e13631 (2021). 
  11. Hagve, T.-A. Effects of unsaturated fatty acids on cell membrane functions. Scandinavian journal of clinical and laboratory investigation 48, 381-388 (1988).  https://doi.org/10.1080/00365518809085746
  12. Litwiniuk, M., Krejner, A., Speyrer, M. S., Gauto, A. R. & Grzela, T. Hyaluronic acid in inflammation and tissue regeneration. Wounds 28, 78-88 (2016). 
  13. Patel, D. P., Swink, S. M. & Castelo-Soccio, L. A review of the use of biotin for hair loss. Skin appendage disorders 3, 166-169 (2017).  https://doi.org/10.1159/000462981
  14. Miniaci, M. C. et al. Cysteine prevents the reduction in keratin synthesis induced by iron deficiency in human keratinocytes. Journal of cellular biochemistry 117, 402-412 (2016).  https://doi.org/10.1002/jcb.25286
  15. Boyera, N., Galey, I. & Bernard, B. Effect of vitamin C and its derivatives on collagen synthesis and cross-linking by normal human fibroblasts. International journal of cosmetic science 20, 151-158 (1998).  https://doi.org/10.1046/j.1467-2494.1998.171747.x
  16. Edgar, S. et al. Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts. Scientific Reports 8, 10474 (2018). 
  17. Sessa, W. Molecular control of blood flow and angiogenesis: role of nitric oxide. Journal of Thrombosis and Haemostasis 7, 35-37 (2009).  https://doi.org/10.1111/j.1538-7836.2009.03424.x
  18. Chen, K., Pittman, R. N. & Popel, A. S. Nitric oxide in the vasculature: where does it come from and where does it go? A quantitative perspective. Antioxid Redox Signal 10, 1185-1198 (2008).  https://doi.org/10.1089/ars.2007.1959
  19. Yoshikawa, T., Naito, Y. & Kondo, M. Ginkgo biloba leaf extract: review of biological actions and clinical applications. Antioxidants & redox signaling 1, 469-480 (1999).  https://doi.org/10.1089/ars.1999.1.4-469
  20. Hermenean, A. et al. Antioxidant and hepatoprotective activity of milk thistle (Silybum marianum L. Gaertn.) seed oil. Open life sciences 10 (2015).