Journal of Sensor Science and Technology (센서학회지)

The Korean Sensors Society (한국센서학회)
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Understanding of the Working Principle of Field-effect Transistor (FET) Biosensor with the Review Of Experimental Measurement Set-up

전계효과트랜지스터(FET) 바이오센서 실험 셋업 분석을 통한 동작원리 이해

  • 이국녕 ((주)위즈바이오솔루션 진단기기연구소)
  • Received : 2023.11.14
  • Accepted : 2023.11.30
  • Published : 2023.11.30
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Abstract

Over the past few decades, considerable research has been conducted on field-effect transistor (FET) biosensors; however, other than electrochemical sensors for pH, they have not reached the commercialization stage and still remain at the basic research level. Although several reports have been published on experiments with real biological samples, no reports exist of developments that have reached commercialization or finalized approval for use. In this paper, we explain the reason for the experiments of FET biosensors to induce spurious signals in an experimental setup and explain the existence of misunderstandings regarding the operating principle of FET biosensors owing to the spurious signals. Based on the thoughtful review of the results of previously published papers, we show that the electrochemical read-out principle of FET biosensors requires our intensive understanding of the interfacial potential between the solution and the sensor electrode for further progress in the FET biosensor research.

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References

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