Acknowledgement
The study was funded by Timab Magnesium.
References
- Sykes BW, Hewetson M, Hepburn RJ, Luthersson N, Tamzali Y. European College of Equine Internal Medicine Consensus Statement--equine gastric ulcer syndrome in adult horses. J Vet Intern Med. 2015;29(5):1288-1299. https://doi.org/10.1111/jvim.13578
- Andrews FM, Sifferman RL, Bernard W, Hughes FE, Holste JE, Daurio CP, et al. Efficacy of omeprazole paste in the treatment and prevention of gastric ulcers in horses. Equine Vet J. 1999;31(29):81-86. https://doi.org/10.1111/j.2042-3306.1999.tb05176.x
- Murray MJ, Haven ML, Eichorn ES, Zhang D, Eagleson J, Hickey GJ. Effects of omeprazole on healing of naturally-occurring gastric ulcers in thoroughbred racehorses. Equine Vet J. 1997;29(6):425-429. https://doi.org/10.1111/j.2042-3306.1997.tb03153.x
- Vokes J, Lovett A, Sykes B. Equine gastric ulcer syndrome: an update on current knowledge. Animals (Basel). 2023;13(7):1261.
- Huff NK, Auer AD, Garza F Jr, Keowen ML, Kearney MT, McMullin RB, et al. Effect of sea buckthorn berries and pulp in a liquid emulsion on gastric ulcer scores and gastric juice pH in horses. J Vet Intern Med. 2012;26(5):1186-1191. https://doi.org/10.1111/j.1939-1676.2012.00975.x
- Murray MJ, Grady TC. The effect of a pectin-lecithin complex on prevention of gastric mucosal lesions induced by feed deprivation in ponies. Equine Vet J. 2002;34(2):195-198. https://doi.org/10.2746/042516402776767268
- Venner M, Lauffs S, Deegen E. Treatment of gastric lesions in horses with pectin-lecithin complex. Equine Vet J. 1999;31(29):91-96. https://doi.org/10.1111/j.2042-3306.1999.tb05178.x
- Bach A, Guasch I, Elcoso G, Duclos J, Khelil-Arfa H. Modulation of rumen pH by sodium bicarbonate and a blend of different sources of magnesium oxide in lactating dairy cows submitted to a concentrate challenge. J Dairy Sci. 2018;101(11):9777-9788. https://doi.org/10.3168/jds.2017-14353
- Leno BM, LaCount SE, Ryan CM, Briggs D, Crombie M, Overton TR. The effect of source of supplemental dietary calcium and magnesium in the peripartum period, and level of dietary magnesium postpartum, on mineral status, performance, and energy metabolites in multiparous Holstein cows. J Dairy Sci. 2017;100(9):7183-7197. https://doi.org/10.3168/jds.2017-12773
- Colombo EA, Cooke RF, Araujo AC, Harvey KM, Pohler KG, Brandao AP. Supplementing a blend of magnesium oxide to feedlot cattle: effects on ruminal, physiological, and productive responses. J Anim Sci. 2022;100(1):skab375.
- Schaefer DM, Wheeler LJ, Noller CH, Keyser RB, White JL. Neutralization of acid in the rumen by magnesium oxide and magnesium carbonate. J Dairy Sci. 1982;65(5):732-739. https://doi.org/10.3168/jds.S0022-0302(82)82260-1
- Le Ruyet P, Tucker WB. Ruminal buffers: temporal effects on buffering capacity and pH of ruminal fluid from cows fed a high concentrate diet. J Dairy Sci. 1992;75(4):1069-1077. https://doi.org/10.3168/jds.S0022-0302(92)77851-5
- Rabuffo TS, Orsini JA, Sullivan E, Engiles J, Norman T, Boston R. Associations between age or sex and prevalence of gastric ulceration in Standardbred racehorses in training. J Am Vet Med Assoc. 2002;221(8):1156-1159. https://doi.org/10.2460/javma.2002.221.1156
- Dionne RM, Vrins A, Doucet MY, Pare J. Gastric ulcers in standardbred racehorses: prevalence, lesion description, and risk factors. J Vet Intern Med. 2003;17(2):218-222. https://doi.org/10.1111/j.1939-1676.2003.tb02437.x
- Roy MA, Vrins A, Beauchamp G, Doucet MY. Prevalence of ulcers of the squamous gastric mucosa in standardbred horses. J Vet Intern Med. 2005;19(5):744-750. https://doi.org/10.1111/j.1939-1676.2005.tb02755.x
- Jonsson H, Egenvall A. Prevalence of gastric ulceration in Swedish Standardbreds in race training. Equine Vet J. 2006;38(3):209-213. https://doi.org/10.2746/042516406776866390
- Bell NJ, Burget D, Howden CW, Wilkinson J, Hunt RH. Appropriate acid suppression for the management of gastro-oesophageal reflux disease. Digestion. 1992;51 Suppl 1:59-67. https://doi.org/10.1159/000200917
- Suzuki H, Nishizawa T, Tsugawa H, Mogami S, Hibi T. Roles of oxidative stress in stomach disorders. J Clin Biochem Nutr. 2012;50(1):35-39. https://doi.org/10.3164/jcbn.11-115SR
- Liu M, Dudley SC Jr. Magnesium, oxidative stress, inflammation, and cardiovascular disease. Antioxidants. 2020;9(10):907.
- Mathew AA, Panonnummal R. 'Magnesium'-the master cation-as a drug-possibilities and evidences. Biometals. 2021;34(5):955-986. https://doi.org/10.1007/s10534-021-00328-7
- Tandon R, Khanna HD, Dorababu M, Goel RK. Oxidative stress and antioxidants status in peptic ulcer and gastric carcinoma. Indian J Physiol Pharmacol 2004;48(1):115-118.
- Ige AO, Adewoye EO, Okwundu NC, Alade OE, Onuobia PC. Oral magnesium reduces gastric mucosa susceptibility to injury in experimental diabetes mellitus. Pathophysiology. 2016;23(2):87-93. https://doi.org/10.1016/j.pathophys.2016.04.003