한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제40권5호
  • /
  • Pages.387-392
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  • 2023
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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A Case of Visceral T Cell Lymphoma with Prominent Histiocyte Infiltration in a Dog

  • Myung-Chul Kim (Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Du-Min Go (Laboratory of Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Sang-Ho Woo (Laboratory of Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Jeong-Seop Oh (Laboratory of Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Dae-Yong Kim (Laboratory of Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Na-Yon Kim (Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Yeseul Yang (Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Jae-Ha Jung (Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Hwa-Young Youn (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University) ;
  • Yongbaek Kim (Laboratory of Veterinary Clinical Pathology, College of Veterinary Medicine, Seoul National University)
  • 투고 : 2023.08.14
  • 심사 : 2023.09.25
  • 발행 : 2023.10.31
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초록

A 13-year-old intact male English Springer Spaniel presented with anorexia. Physical examination revealed a palpable abdominal mass without peripheral lymphadenopathy. Ultrasonography revealed hepatosplenomegaly and a markedly enlarged hepatic lymph node. Fine-needle aspiration of the splenic and nodal lesions revealed atypical round cells admixed with numerous histiocytes. The dog was euthanized owing to deteriorating condition despite a month of chemotherapy with lomustine. Histopathology revealed obliteration of the normal architecture of the liver, spleen, kidney, and hepatic and mesenteric lymph nodes by CD3+ neoplastic lymphocytes, accompanied by extensive F4/80+ histiocytic infiltration. This report describes a rare presentation of T-cell lymphoma with prominent histiocytic infiltration that may initially be misdiagnosed as histiocytic neoplasia in a dog.

키워드

과제정보

This study was supported by the Brain Korea 21 Program, Research Institute of Veterinary Sciences, College of Veterinary Medicine, and Seoul National University.

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