Textile Science and Engineering (한국섬유공학회지)

The Korean Fiber Society (한국섬유공학회)
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Study on Mechanical Properties and Biocompatibility of PVA/CNC Biomaterial Hydrogel

PVA/CNC 바이오소재 하이드로겔의 기계적 물성과 생체적합성 연구

  • Young Ho Seo (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University) ;
  • Sun Mi Zo (School of Chemical Engineering, Yeungnam University) ;
  • Sung Soo Han (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University) ;
  • Tae Hwan Oh (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University)
  • 서영호 (영남대학교 대학원 유기신소재공학과) ;
  • 조선미 (영남대학교 화학공학부) ;
  • 한성수 (영남대학교 대학원 유기신소재공학과) ;
  • 오태환 (영남대학교 대학원 유기신소재공학과)
  • Received : 2023.10.01
  • Accepted : 2023.10.25
  • Published : 2023.10.31
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Abstract

In this study, PVA (polyvinyl alcohol) and CNC (cellulose nano-crystal) composite hydrogel was manufactured and the effect of CNC content less than 1 wt% was investigated on the mechanical properties and cell viability. The CNC was utilized to enhance the compressive stress of the PVA hydrogel. We have focused on a low content of CNC less than 1 wt% because CNC is very expensive to use as an additive. The fabrication of PVA/CNC hydrogels with CNC contents of 0.25, 0.50, and 0.75 wt% was done using solvent casting and freeze-thawing physical cross-linking method. The compressive strength of the PVA/CNC hydrogel with a CNC content of 0.75 wt% was improved up to 95% higher than that of pristine PVA. Furthermore, through MTT and DAPI staining experiments, PVA/CNC hydrogels exhibited no toxicity and good cell viability due to the smooth proliferation of cells.

Keywords

Acknowledgement

본 연구는 첨단바이오신소재기술개발사업(과제번호 20008490)의 지원을 받아 수행된 과제로 이에 감사드립니다.

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