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Study on Mechanical Properties and Biocompatibility of Scaffold Made of Using PLA Mesh Fabric

PLA Mesh 직물 지지체의 기계적 물성 및 생체적합성 연구

  • Young Ho Seo (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University) ;
  • Sun Mi Zo (School of Chemical Engineering, Yeungnam University) ;
  • Sung Soo Han (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University) ;
  • Tae Hwan Oh (Department of Advenced Organic Materials Engineering, Graduate School, Yeungnam University)
  • 서영호 (영남대학교 대학원 유기신소재공학과) ;
  • 조선미 (영남대학교 화학공학부) ;
  • 한성수 (영남대학교 대학원 유기신소재공학과) ;
  • 오태환 (영남대학교 대학원 유기신소재공학과)
  • Received : 2023.10.02
  • Accepted : 2023.10.22
  • Published : 2023.10.31

Abstract

In this study, PLA scaffolds was manufactured by using PLA mesh fabric for tea-bags, and the effects of hot press temperature on mechanical properties, morphology, and cell viability were investigated. Research was focused on whether PLA mesh fabric for tea-bags can be used as a scaffold. PLA scaffolds were manufactured by laminating five layers of PLA mesh fabric that rotated at a 45 degree angle and the layers are hot pressed at 120, 130, 140, and 150 ℃. As the hot press temperature increased to 140 ℃, the tensile strength increased. SEM photographs showed that micro pores were formed well at 120 and 130 ℃. Non-toxicity and biocompatibility of the PLA mesh scaffold were revealed via MTT assay for cell viablity and DAPI staining experiments. We developed PLA scaffolds made of mesh fabric and showed the possibility thereof as scaffolds.

Keywords

Acknowledgement

본 연구는 산업통상자원부 첨단바이오신소재기술개발사업(과제번호 20008490)과 국제공동기술개발사업(과제번호 P0022396)의 지원을 받아 수행된 과제로 이에 감사드립니다.

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