Journal of Medicine and Life Science

Institute for Medical Science (제주대학교 의과학연구소)
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Effect of rheumatoid arthritis on primary total knee arthroplasty and revision arthroplasty

류마티스관절염이 슬관절치환술과 슬관절재치환술에 미치는 영향

  • Wooseong Jeong (Department of Internal Medicine, Jeju National University College of Medicine) ;
  • Oh-Sung Kwon (Department of Medical Information, Jeju National University Hospital) ;
  • Sung Wook Song (Department of Emergency Medicine, Jeju National University College of Medicine)
  • 정우성 (제주대학교 의과대학 내과학교실) ;
  • 권오성 (제주대학교병원 의료정보과) ;
  • 송성욱 (제주대학교 의과대학 응급의학교실)
  • Received : 2023.02.09
  • Accepted : 2023.03.03
  • Published : 2023.03.31
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Abstract

The demand for total knee arthroplasty (TKA) is rapidly increasing worldwide. The most common indication for TKA is osteoarthritis (OA); however, some patients with rheumatoid arthritis (RA) also undergo TKA. This study aimed to investigate the effects of RA on TKA. Our findings revealed that patients with RA underwent TKA at a younger age than did patients with OA. However, contrary to the findings of pre-21st century studies, the average age of TKA among patients with RA was not significantly different from that of patients with OA. Additionally, patients with RA had a 1.5-fold higher risk of undergoing TKA. Although not statistically significant, patients with RA had a higher revision TKA rate, a shorter time until revision TKA, and underwent more revision TKAs due to infections than did patients with OA. An analysis of factors that affect revision TKA revealed that the risk of revision increased if the erythrocyte sedimentation rate and C-reactive protein levels were increased at the time of TKA. This study showed that patients with RA have a slightly higher risk of undergoing TKA than did patients with OA. Furthermore, the presence of inflammation at the time of TKA increases the risk of revision; therefore, inflammation should be adequately controlled before performing TKA.

Keywords

Acknowledgement

이 연구는 2018년 제주대학교병원 연구비 지원으로 수행되었다.

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