한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제40권4호
  • /
  • Pages.283-287
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  • 2023
  • /
  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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A Case of Choroidal Melanocytoma with Optic Nerve Involvement in a Dog

  • Jinseon Chang (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Dajeong Jeong (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Seonmi Kang (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Kangmoon Seo (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • 투고 : 2023.05.04
  • 심사 : 2023.07.18
  • 발행 : 2023.08.31
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초록

A 10-year-old spayed female beagle dog presented with a 2-month history of third-eyelid elevation in the left eye (OS). Ophthalmic examination revealed slightly diminished corneal and palpebral reflexes along with exophthalmos in the OS. Schirmer's tear test and intraocular pressure values were within the normal range for the OS. Slit-lamp biomicroscopy revealed protrusion of the third eyelid and corneal opacity in the OS. Fundoscopy revealed a prominent black mass in the OS covering the optic nerve. Tapetal hyper-reflectivity was also observed around the mass. Ocular ultrasonography showed a 0.74 × 0.67 cm echogenic posterior segment mass around the optic nerve protruding into the retrobulbar space. Computed tomography revealed a contrast-enhanced soft tissue lesion in the posteromedial aspect of the left eyeball protruding into the retrobulbar region, and the optic nerve was suspected to be involved. No evidence of osteolytic changes in the adjacent bone or distant metastasis was observed. Enucleation was performed to prevent potential metastasis or local invasion of the mass and to relieve discomfort due to exposure to keratopathy resulting from lagophthalmos. Histopathological examination revealed a central choroidal melanocytoma extending into the optic nerve. No local recurrence was detected until 16 months postoperatively.

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참고문헌

  1. Aguirre GD, Brown G, Shields JA, Dubielzig RR. Melanoma of the choroid in a dog. J Am Anim Hosp Assoc 1984; 20: 471-476.
  2. Badanes Z, Espinheira Gomes F, Ledbetter EC. Choroidal melanocytic tumors in dogs: a retrospective study. Vet Ophthalmol 2020; 23: 987-993. https://doi.org/10.1111/vop.12839
  3. Collinson PN, Peiffer RL. Clinical presentation, morphology and behavior of primary choroidal melanomas in eight dogs. Prog Comp Vet Ophthalmol 1993; 3: 158-164.
  4. Dubielzig RR. Ocular neoplasia in small animals. Vet Clin North Am Small Anim Pract 1990; 20: 837-848. https://doi.org/10.1016/S0195-5616(90)50064-9
  5. Dubielzig RR, Aguirre GD, Gross SL, Diters RW. Choroidal melanomas in dogs. Vet Pathol 1985; 22: 582-585. https://doi.org/10.1177/030098588502200612
  6. Dziezyc J, Hager DA, Millichamp NJ. Two-dimensional real-time ocular ultrasonography in the diagnosis of ocular lesions in dogs. J Am Anim Hosp Assoc 1987; 23: 501-508.
  7. Hyman JA, Koch SA, Wilcock BP. Canine choroidal melanoma with metastases. Vet Ophthalmol 2002; 5: 113-117. https://doi.org/10.1046/j.1463-5224.2002.00227.x
  8. Labelle AL, Labelle P. Canine ocular neoplasia: a review. Vet Ophthalmol 2013; 16 Suppl 1: 3-14. https://doi.org/10.1111/vop.12062
  9. Miwa Y, Matsunaga S, Kato K, Ogawa H, Nakayama H, Tsujimoto S, et al. Choroidal melanoma in a dog. J Vet Med Sci 2005; 67: 821-823. https://doi.org/10.1292/jvms.67.821
  10. Morgan RV, Patton CS. Choroidal melanoma in a dog. Cornell Vet 1993; 83: 211-217.
  11. Schoster JV, Dubielzig RR, Sullivan L. Choroidal melanoma in a dog. J Am Vet Med Assoc 1993; 203: 89-91. https://doi.org/10.2460/javma.1993.203.01.89
  12. Weisse I, Frese K, Meyer D. Benign melanoma of the choroid in a beagle: ophthalmological, light and electron microscopical investigations. Vet Pathol 1985; 22: 586-591. https://doi.org/10.1177/030098588502200613
  13. Wilcock BP, Peiffer RL Jr. Morphology and behavior of primary ocular melanomas in 91 dogs. Vet Pathol 1986; 23: 418-424. https://doi.org/10.1177/030098588602300411
  14. Withrow SJ, Vail DM, Page RL. Withrow and MacEwen's small animal clinical oncology. 5th ed. St. Louis: Saunders. 2013: 597-606.