DOI QR코드

DOI QR Code

Clinical Impact of Patient's Head Position in Supraclavicular Irradiation of the Whole Breast Radiotherapy

  • Surega Anbumani (Department of Radiation Oncology, HCG Bangalore Institute of Oncology) ;
  • Lohith G. Reddy (Department of Radiation Oncology, HCG Bangalore Institute of Oncology) ;
  • Priyadarshini V (Department of Radiation Oncology, HCG Bangalore Institute of Oncology) ;
  • Sasikala P (Department of Radiation Oncology, HCG Bangalore Institute of Oncology) ;
  • Ramesh S. Bilimagga (Department of Radiation Oncology, HCG Bangalore Institute of Oncology)
  • 투고 : 2022.10.24
  • 심사 : 2023.02.05
  • 발행 : 2023.03.31

초록

Patients with breast cancer can be positioned with their head turned to the contra lateral side or with their head straight during the radiation therapy treatment set-up. In our hospital, patients with locally advanced breast cancer who were receiving radiation therapy have experienced swallowing difficulty after 2 weeks of irradiation. In this pilot study, the impact of head position on reducing dysphagia occurrence was dosimetrically evaluated. Patients were divided into two groups viz., HT (head turned to the contra lateral side of the breast) and HS (head straight) with 10 members in each. Treatment planning was performed, and the dosimetric parameters such as Dmin, Dmax, Dmean, V5, V10, V20, V30, V40, and V50 of both groups were extracted from the dose volume histogram (DVH) of esophagus. The target coverage in the supraclavicular fossa (SCF) region was analyzed using D95 and D98; moreover, the dose heterogeneity was assessed with D2 from the DVHs. The average values of the dose volume parameters were 27.6%, 58.6%, 35.4%, 19%, 13.8%, 14.1%, 11.8%, 8.4%, and 8.1% higher in the HT group compared with those in the HS group. Furthermore, for the SCF, the mean values of D98, D95, and D2 were 42.4, 47.5, and 54 Gy, respectively, in the HS group and 38.9, 45.35, and 55.5 Gy, respectively, in the HT group. This pilot study attempts to give a solution for the poor quality of life of patients after breast radiotherapy due to dysphagia. The findings confirm that the head position could play a significant role in alleviating esophageal toxicity without compromising tumor control.

키워드

과제정보

The authors would like to thank all fellow colleagues in Radiation Oncology department, Bangalore Institute of Oncology (A unit of Healthcare Global Enterprises Ltd.,), India.

참고문헌

  1. Breastcancer.org. Difficulty swallowing, a radiation side efffect? Ardmore: Breastcancer.org., 2009 [cited 2022 Oct 24]. Available from: https://community.breastcancer.org/forum/70/topics/740460.
  2. Belderbos J, Heemsbergen W, Hoogeman M, Pengel K, Rossi M, Lebesque J. Acute esophageal toxicity in non-small cell lung cancer patients after high dose conformal radiotherapy. Radiother Oncol. 2005;75:157-164. https://doi.org/10.1016/j.radonc.2005.03.021
  3. Belkacemi Y, Gligorov J, Ozsahin M, Marsiglia H, De Lafontan B, Laharie-Mineur H, et al. Concurrent trastuzumab with adjuvant radiotherapy in HER2-positive breast cancer patients: acute toxicity analyses from the French multicentric study. Ann Oncol. 2008;19:1110-1116. https://doi.org/10.1093/annonc/mdn029
  4. Ragaz J, Olivotto IA, Spinelli JJ, Phillips N, Jackson SM, Wilson KS, et al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst. 2005;97:116-126. https://doi.org/10.1093/jnci/djh297
  5. Bradley J, Deasy JO, Bentzen S, El-Naqa I. Dosimetric correlates for acute esophagitis in patients treated with radiotherapy for lung carcinoma. Int J Radiat Oncol Biol Phys. 2004;58:1106-1113. https://doi.org/10.1016/j.ijrobp.2003.09.080
  6. Hirota S, Tsujino K, Endo M, Kotani Y, Satouchi M, Kado T, et al. Dosimetric predictors of radiation esophagitis in patients treated for non-small-cell lung cancer with carboplatin/paclitaxel/radiotherapy. Int J Radiat Oncol Biol Phys. 2001;51:291-295. https://doi.org/10.1016/S0360-3016(01)01648-0
  7. Radiation Therapy Oncology Group (RTOG). Breast cancer atlas for radiation therapy planning: consensus definitions. Philadelphia: RTOG; 2014.
  8. Federle MP, Rosado-de-christenson ML, Woodward PJ, Abbott GF. Diagnostic and surgical imaging anatomy: chest, abdomen, pelvis. Philadelphia: Lippincott Williams & Wilkins; 2006.
  9. Moore KL. Clinically oriented anatomy. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 1992.
  10. Lewis WH. Gray's anatomy of the human body. 20th ed. New York: Barlteby.com; 2000.
  11. Jabbour SK, Hashem SA, Bosch W, Kim TK, Finkelstein SE, Anderson BM, et al. Upper abdominal normal organ contouring guidelines and atlas: a Radiation Therapy Oncology Group consensus. Pract Radiat Oncol. 2014;4:82-89. https://doi.org/10.1016/j.prro.2013.06.004
  12. Maguire PD, Sibley GS, Zhou SM, Jamieson TA, Light KL, Antoine PA, et al. Clinical and dosimetric predictors of radiation-induced esophageal toxicity. Int J Radiat Oncol Biol Phys. 1999;45:97-103. https://doi.org/10.1016/S0360-3016(99)00163-7