The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report on the Improvement of Cancer Pain in a Patient with Metastatic Non-Small Cell Lung Cancer Through Herbal Medicine-based Integrative Cancer Treatment with Chemotherapy

항암화학요법과 병행한 한의기반 통합암치료를 통한 전이성 비소세포폐암 환자의 암성 통증 호전 증례보고

  • Young-min Cho (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Jae-ho Yang (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Han-eum Joo (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • So-jeong Park (Dept. of Korean Internal Medicine, Korean Medicine Hospital of Pusan National University) ;
  • Ji-hye Park (East-West Cancer Center, Seoul Korean Medicine Hospital of Daejeon University) ;
  • Hwa-seung Yoo (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University)
  • 조영민 (대전대학교 대전한방병원 동서암센터) ;
  • 양재호 (대전대학교 대전한방병원 동서암센터) ;
  • 주한음 (대전대학교 대전한방병원 동서암센터) ;
  • 박소정 (부산대학교 한방병원 한방내과) ;
  • 박지혜 (대전대학교 서울한방병원 동서암센터) ;
  • 유화승 (대전대학교 대전한방병원 동서암센터)
  • Received : 2023.05.31
  • Accepted : 2023.07.05
  • Published : 2023.06.30
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Abstract

Objective: To demonstrate an improvement in metastatic cancer pain and a decrease in tumor size in a patient with non-small cell lung cancer. Method: A 53-year-old female patient diagnosed with metastatic non-small cell lung cancer in August 2022 underwent integrative cancer treatment (ICT) for two months to decrease the tumor size and improve back pain from bone metastasis. The patient underwent chemotherapy with ICT. Radiologic outcomes were assessed by chest, abdomen, and pelvis computed tomography based on the Response Evaluation Criteria in Solid Tumors (RECIST) protocol. Clinical outcomes were assessed using National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Eastern Cooperative Oncology Group (ECOG), and a numeric rating scale (NRS). Result: During the two months of treatment, the NRS scores for back pain were improved, and the ECOG score improved from grade 2 to 1. The size and metabolic activity of the primary lung tumor decreased and underwent partial remission based on RECIST. No serious side effects of grade 3 or higher were noted on the NCI-CTCAE test. Conclusion: This case suggests that ICT may have a therapeutic effect for cancer pain and a synergetic effect with chemotherapy for metastatic non-small cell lung cancer.

Keywords

Acknowledgement

이 연구는 보건복지부 한국보건산업진흥원 한의약선도기술개발사업의 지원에 의하여 이루어진 것임(과제고유번호: HI19C1046).

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