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자기공명유속계 (MRV) 에서 3차원 다중경로 선적분법을 활용한 비침습적 압력예측 방법 개발

Development of Non-Invasive Pressure Estimation Using 3D Multi-Path Line Integration Method from Magnetic Resonance Velocimetry (MRV)

  • 무함마드 하피즈 아리푸딘 ;
  • 장일훈 ;
  • 송시몬
  • Muhammad Hafidz Ariffudin (Department of mechanical engineering, Hanyang Univ.) ;
  • Ilhoon Jang (Department of mechanical engineering, Hanyang Univ.) ;
  • Simon Song (Department of mechanical engineering, Hanyang University)
  • 투고 : 2023.05.24
  • 심사 : 2023.07.09
  • 발행 : 2023.07.31

초록

The pressure difference across stenotic blood vessels is a commonly used clinical metric for diagnosing many cardiovascular diseases. At present, most clinical pressure measurements rely solely on invasive catheterization. In this study, we propose a novel method for non-invasive pressure estimation using the incompressible Navier-Stokes equations and a 3D multi-path integration approach. We verify spatio-temporal convergence on an in-silico dataset of a cylindrical straight pipe phantom with steady and pulsatile flow fields. We then evaluate the proposed method on an in vitro dataset of reconstructed control, pre-operative, and post-operative carotid artery cases acquired from 4D flow MRI. The performance of our method is compared to existing approaches based on the pressure Poisson equation and work-energy relative pressure. The results demonstrate the proposed method's high accuracy, robustness to spatio-temporal subsampling, and reduced sensitivity to noise, highlighting its great potential for non-invasive pressure estimation.

키워드

과제정보

이 논문은 2021년도 정부(과학기술정보통신부)의 재원으로 한국연구재단의 지원을 받아 수행된 연구임(NRF-2021R1A2B5B03002103).

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