DOI QR코드

DOI QR Code

Treatment of descemetocele with deep keratotomy combined with a nictitating membrane flap in a dog

  • Manbok Jeong (Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University)
  • 투고 : 2023.05.07
  • 심사 : 2023.06.23
  • 발행 : 2023.06.30

초록

A 10-year-old, spayed female, Maltese dog presented with a 2-day history of severe left eye squint. Slit-lamp biomicroscopy showed a deep corneal defect stained into a doughnut shape together with hypopyon in the anterior chamber. Based on these results, a diagnosis of descemetocele and uveitis in the left eye was made. Deep keratotomy combined with a nictitating membrane flap effectively resolved the descemetocele without complications. The surgical procedures performed on this patient were easy and effective, and could be used as an alternative to graft surgery for descemetocele treatment.

키워드

과제정보

The author would like to thank Songhui Lee, in the Department of Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, for assistance with illustrations and graphics.

참고문헌

  1. Ledbetter EC, Gilger BC. Diseases and Surgery of the Canine Cornea and Sclera. In: Gelatt KN, Gilger BC, Kern TJ, eds. Veterinary Ophthalmology. 5th ed. pp. 976-1049, Wiley Blackwell, Ames, 2013.
  2. Hakanson NE, Merideth RE. Conjunctival pedicle grafting in the treatment of corneal ulcers in the dog and cat. J Am Hosp Assoc 1987;23:641-648.
  3. Wilkie DA, Whittaker C. Surgery of the cornea. Vet Clin North Am Small Anim Pract 1997;27:1067-1107. https://doi.org/10.1016/S0195-5616(97)50104-5
  4. Boutin MP, Coutellier M, Ollivier FJ. Cotton-tip debridement, scalpel blade debridement, and superficial grid keratotomy for treatment of spontaneous chronic corneal epithelial defects (SCCED): a retrospective evaluation of 308 cases. Vet Ophthalmol 2020;23:979-986. https://doi.org/10.1111/vop.12838
  5. Helper LC, Blogg R. A modified third eyelid flap procedure. J Am Anim Hosp Assoc 1983;18:955-956.
  6. Maggs D. Corena and Sclera. In: Maggs D, Miller P, Ofri R, eds. Slatter's Fundamentals of Veterinary Ophthalmology. 5th ed. pp. 184-219, Elsevier, St. Louis, 2013.
  7. Kim JM, Kim JC, Park WC, Seo JS, Chang HR. Effect of thermal preconditioning before excimer laser photoablation. J Korean Med Sci 2004;19:437-446. https://doi.org/10.3346/jkms.2004.19.3.437
  8. Zhang J, Huang C, Feng Y, Li Y, Wang W. Comparison of beneficial factors for corneal wound-healing of rat mesenchymal stem cells and corneal limbal stem cells on the xenogeneic acellular corneal matrix in vitro. Mol Vis 2012;18:161-173.
  9. Peterson CW, Carter RT, Bentley E, Murphy CJ, Chandler HL. Heat-shock protein expression in canine corneal wound healing. Vet Ophthalmol 2016;19:262-266. https://doi.org/10.1111/vop.12302
  10. Morita M, Fujita N, Takahashi A, Nam ER, Yui S, Chung CS, Kawahara N, Lin HY, Tsuzuki K, Nakagawa T, Nishimura R. Evaluation of ABCG2 and p63 expression in canine cornea and cultivated corneal epithelial cells. Vet Ophthalmol 2015;18:59-68. https://doi.org/10.1111/vop.12147
  11. Cenedella RJ, Fleschner CR. Kinetics of corneal epithelium turnover in vivo. Studies of lovastatin. Invest Ophthalmol Vis Sci 1990;31:1957-1962.
  12. Shoshani Y, Pe'er J, Doviner V, Frucht-Pery J, Solomon A. Increased expression of inflammatory cytokines and matrix metalloproteinases in pseudophakic corneal edema. Invest Ophthalmol Vis Sci 2005;46:1940-1947. https://doi.org/10.1167/iovs.04-1203