Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지
DOI QR코드

DOI QR Code

Korean farm animal veterinarians' perception and practice of prudent use of antimicrobials

한국 농장동물 수의사의 항생제 신중사용에 대한 인식과 실천

  • Yoojin Choi (Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Seola Joo (Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Sang-Won Lee (College of Veterinary Medicine, Konkuk University) ;
  • Hong-Jae Lee (College of Veterinary Medicine, Konkuk University) ;
  • Myung-Sun Chun (Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University)
  • 최유진 (서울대학교 수의과대학 수의과학연구소) ;
  • 주설아 (서울대학교 수의과대학 수의과학연구소) ;
  • 이상원 (건국대학교 수의과대학) ;
  • 이홍재 (건국대학교 수의과대학) ;
  • 천명선 (서울대학교 수의과대학 수의과학연구소)
  • Received : 2023.03.03
  • Accepted : 2023.05.03
  • Published : 2023.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Antimicrobial (AM) resistance is a growing threat in human and veterinary medicine, spreading across species and perceived as One-Health issue. Prudent use of AM products is essential in mitigating this risk in both human and veterinary medicine. Farm veterinarians, responsible for prescribing appropriate AM and offering advice to farmers on their proper usage, are regarded as key players in the livestock industry. An online survey of farm veterinarians (n = 1,531) was conducted to assess their educational experience, beliefs, current status of prescription, practical behavior, and self-efficacy regarding the prudent use of antimicrobials (PUA). The data from 170 respondents were analyzed using descriptive statistics, regression and mediation analysis. Participants chose AM based on their experiences, academic resources, and peer veterinarians. Approximately 77% did not routinely conduct antibiotic-susceptibility-test. Most participants believed in the importance of PUA and the role of veterinarians to reduce AM resistance, but they reported a lack of awareness among farmers and insufficient national support interfere with their practical behavior with regard to PUA. Half of the participants had PUA-education, and 78.6% reported that education had a positive impact on their behavior with PUA. Self-efficacy partly mediates the relationship between belief and behavior for PUA, which accounted for 23.77% of the total effect that beliefs have on behavior for PUA. The findings of the study show that enhancing veterinarians' abilities to practice and their self-efficacy through education tailored to the current status of farms can contribute to the reduction of AMs in the livestock sector.

Keywords

Acknowledgement

This research was supported by a grant (Z-1543079-2019-20-01) from the Animal and Plant Quarantine Agency (APQA), Republic of Korea.

References

  1. Centers for Disease Control and Prevention (CDC). Antibiotic resistance threats in the United States [Internet] CDC; 2019 [cited 2022 Jan 29]. Available from: https://www.cdc.gov/drugresistance/biggest-threats.html.
  2. de Kraker ME, Stewardson AJ, Harbarth S. Will 10 million people die a year due to antimicrobial resistance by 2050? PLoS Med 2016;13:e1002184.
  3. Barbosa TM, Levy SB. The impact of antibiotic use on resistance development and persistence. Drug Resist Updat 2000;3:303-311. https://doi.org/10.1054/drup.2000.0167
  4. Thanner S, Drissner D, Walsh F. Antimicrobial resistance in agriculture. mBio 2016;7:e02227-e02215.
  5. Robinson TP, Bu DP, Carrique-Mas J, Fevre EM, Gilbert M, Grace D, Hay SI, Jiwakanon J, Kakkar M, Kariuki S, Laxminarayan R, Lubroth J, Magnusson U, Thi Ngoc P, Van Boeckel TP, Woolhouse ME. Antibiotic resistance is the quintessential One Health issue. Trans R Soc Trop Med Hyg 2016;110:377-380. https://doi.org/10.1093/trstmh/trw048
  6. Van Boeckel TP, Glennon EE, Chen D, Gilbert M, Robinson TP, Grenfell BT, Levin SA, Bonhoeffer S, Laxminarayan R. Reducing antimicrobial use in food animals. Science 2017;357:1350-1352. https://doi.org/10.1126/science.aao1495
  7. Ministry of Agriculture(MAF), Food and Rural Affairs (MAFRA). Nationwide Surveillance on Antimicrobial Use and Resistance. MAFRA, Sejong, 2021.
  8. Cattaneo AA, Wilson R, Doohan D, LeJeune JT. Bovine veterinarians' knowledge, beliefs, and practices regarding antibiotic resistance on Ohio dairy farms. J Dairy Sci 2009;92:3494-3502. https://doi.org/10.3168/jds.2008-1575
  9. Speksnijder DC, Jaarsma DA, Verheij TJ, Wagenaar JA. Attitudes and perceptions of Dutch veterinarians on their role in the reduction of antimicrobial use in farm animals. Prev Vet Med 2015;121:365-373. https://doi.org/10.1016/j.prevetmed.2015.08.014
  10. De Briyne N, Atkinson J, Pokludova L, Borriello SP, Price S. Factors influencing antibiotic prescribing habits and use of sensitivity testing amongst veterinarians in Europe. Vet Rec 2013;173:475.
  11. Norris JM, Zhuo A, Govendir M, Rowbotham SJ, Labbate M, Degeling C, Gilbert GL, Dominey-Howes D, Ward MP. Factors influencing the behaviour and perceptions of Australian veterinarians towards antibiotic use and antimicrobial resistance. PLoS One 2019;14:e0223534.
  12. Visschers VH, Backhans A, Collineau L, Loesken S, Nielsen EO, Postma M, Belloc C, Dewulf J, Emanuelson U, Grosse Beilage E, Siegrist M, Sjolund M, Stark KD. A comparison of pig farmers' and veterinarians' perceptions and intentions to reduce antimicrobial usage in six European countries. Zoonoses Public Health 2016;63:534-544. https://doi.org/10.1111/zph.12260
  13. McDougall S, Compton C, Botha N. Factors influencing antimicrobial prescribing by veterinarians and usage by dairy farmers in New Zealand. N Z Vet J 2017;65:84-92. https://doi.org/10.1080/00480169.2016.1246214
  14. Hong KS. The Study on Regulatory Measures for Appropriate Use of Antibiotics in Animals [thesis]. Yeonsei University, Seoul, 2005.
  15. Kim SJ, Moon DC, Mechesso AF, Kang HY, Song HJ, Na SH, Choi JH, Yoon SS, Lim SK. Nationwide Surveillance on Antimicrobial Resistance Profiles of Staphylococcus aureus Isolated from Major Food Animal Carcasses in South Korea During 2010-2018. Foodborne Pathog Dis 2021;18:388-397. https://doi.org/10.1089/fpd.2020.2899
  16. Moon DC, Kim SJ, Mechesso AF, Kang HY, Song HJ, Choi JH, Yoon SS, Lim SK. Mobile colistin resistance gene mcr-1 detected on an IncI2 plasmid in Salmonella typhimurium sequence type 19 from a healthy pig in South Korea. Microorganisms 2021;9:398.
  17. Herzog H, Grayson S, McCord D. Brief measures of the animal attitude scale. Anthrozoos 2015;28:145-152. https://doi.org/10.2752/089279315X14129350721894
  18. Herzog Jr HA, Betchart NS, Pittman RB. Gender, sex role orientation, and attitudes toward animals. Anthrozoos 1991;4:184-191. https://doi.org/10.2752/089279391787057170
  19. Nuangmek A, Rojanasthien S, Yano T, Yamsakul P, Chotinun S, Tadee P. Knowledge, attitudes and practices toward antimicrobial usage: a cross-sectional study of layer and pig farm owners/managers in Chiang Mai, Lamphun, and Chonburi provinces, Thailand, May 2014 to February 2016. Korean J Vet Res 2018;58:17-25. https://doi.org/10.14405/kjvr.2018.58.1.17
  20. OIE, World Organisation for Animal Health. OIE List of Antimicrobial Agents of Veterinary Importance. OIE, World Organisation for Animal Health, Paris, 2018.
  21. Golding SE, Ogden J, Higgins HM. Examining the effect of context, beliefs, and values on UK farm veterinarians' antimicrobial prescribing: a randomized experimental vignette and cross-sectional survey. Antibiotics (Basel) 2021;10:445.
  22. Bandura A. Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev 1977;84:191-215. https://doi.org/10.1037/0033-295X.84.2.191
  23. Anderson ES, Winett RA, Wojcik JR, Williams DM. Social cognitive mediators of change in a group randomized nutrition and physical activity intervention: social support, self-efficacy, outcome expectations and self-regulation in the guide-to-health trial. J Health Psychol 2010;15:21-32. https://doi.org/10.1177/1359105309342297
  24. Kim MY, Lee HK. A study on the influence factors of self-efficacy, job performance, and job satisfaction of university hospital nurses. J Korean Appl Sci Technol 2019;36:726-736.
  25. Son IB. The mediating effects of self-efficacy on the association between person-environment fit and job performance perceived by social workers in vocational rehabilitation facility for people with disabilities. GRI Rev 2019;21:207-235.
  26. Cake MA, Bell MA, Williams JC, Brown FJ, Dozier M, Rhind SM, Baillie S. Which professional (non-technical) competencies are most important to the success of graduate veterinarians?: a Best Evidence Medical Education (BEME) systematic review: BEME Guide No. 38. Med Teach 2016;38:550-563. https://doi.org/10.3109/0142159X.2016.1173662
  27. Korean Veterinary Medical Association; Accreditation Board for Veterinary Education in Korea. Forecasting the Demand for and Supply of Veterinary workforce in Korea. Korean Veterinary Medical Association, Accreditation Board for Veterinary Education in Korea, Seongnam, 2016.
  28. Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: a Regression-Based Approach. The Guilford Press, New York, 2013.
  29. Schweizer ML, Perencevich EN, Eber MR, Cai X, Shardell MD, Braykov N, Laxminarayan R. Optimizing antimicrobial prescribing: are clinicians following national trends in methicillin-resistant staphylococcus aureus (MRSA) infections rather than local data when treating MRSA wound infections. Antimicrob Resist Infect Control 2013;2:28.
  30. Tree M, McDougall S, Beggs DS, Robertson ID, Lam TJ, Aleri JW. Antimicrobial use on Australian dairy cattle farms: a survey of veterinarians. Prev Vet Med 2022;202:105610.
  31. Skjolstrup NK, Vaarst M, Jensen CS, Lastein DB. Danish cattle veterinarians' perspectives on antimicrobial use: contextual and individual influencing factors. J Dairy Sci 2022;105:3377-3393. https://doi.org/10.3168/jds.2021-20981
  32. Coyne LA, Latham SM, Williams NJ, Dawson S, Donald IJ, Pearson RB, Smith RF, Pinchbeck GL. Understanding the culture of antimicrobial prescribing in agriculture: a qualitative study of UK pig veterinary surgeons. J Antimicrob Chemother 2016;71:3300-3312. https://doi.org/10.1093/jac/dkw300
  33. Zhuo A, Labbate M, Norris JM, Gilbert GL, Ward MP, Bajorek BV, Degeling C, Rowbotham SJ, Dawson A, Nguyen KA, Hill-Cawthorne GA, Sorrell TC, Govendir M, Kesson AM, Iredell JR, Dominey-Howes D. Opportunities and challenges to improving antibiotic prescribing practices through a One Health approach: results of a comparative survey of doctors, dentists and veterinarians in Australia. BMJ Open 2018;8:e020439.
  34. Grondal H, Blanco-Penedo I, Fall N, Sternberg-Lewerin S. Trust, agreements, and occasional breakdowns: veterinarians' perspectives on farmer-veterinarian relationships and use of antimicrobials for Swedish dairy cattle. J Dairy Sci 2023;106:534-546. https://doi.org/10.3168/jds.2022-21834
  35. Padda H, Wemette M, Safi AG, Beauvais W, Shapiro MA, Moroni P, Ivanek R. New York State dairy veterinarians' perceptions of antibiotic use and resistance: a qualitative interview study. Prev Vet Med 2021;194:105428.
  36. Mazza F, Scali F, Formenti N, Romeo C, Tonni M, Ventura G, Bertocchi L, Lorenzi V, Fusi F, Tolini C, Clemente GF, Guadagno F, Maisano AM, Santucci G, Candela L, Romeo GA, Alborali GL. The relationship between animal welfare and antimicrobial use in Italian dairy farms. Animals (Basel) 2021;11:2575.
  37. Kunstler BE, Lennox A, Bragge P. Changing prescribing behaviours with educational outreach: an overview of evidence and practice. BMC Med Educ 2019;19:311.