Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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Mercury exposure is associated with obesity: a systematic review and meta-analysis

  • Jimin Jeon (Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine) ;
  • Kyong Park (Department of Food and Nutrition, Yeungnam University)
  • Received : 2023.05.17
  • Accepted : 2023.06.15
  • Published : 2023.06.30
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Abstract

Objectives: Previous studies have evaluated the association between mercury exposure and obesity but have yielded mixed conclusions. The aim of this study was to systematically review and summarize scientific evidence regarding the association between mercury exposure and obesity in the human population. Methods: We conducted a systematic search of PubMed, Web of Science, Scopus, and Science Direct for articles related to mercury exposure and obesity. Meta-analyses of the highest and lowest categories of mercury levels were evaluated using a random effects model. Begg's test was used to detect publication bias. Results: A total of 9 articles were included. The pooled random effects odds ratio (OR) for mercury exposure and obesity of all 9 studies was 1.66 (95% confidence interval [CI]: 1.16-2.38). This positive association was evident in adults (OR: 1.61, 95% CI: 1.02-2.54) and among studies with Asian populations (OR: 2.00, 95% CI: 1.53-2.59), but not among those with North America/African populations (OR: 0.90, 95% CI: 0.50-1.65). Conclusions: The present meta-analysis identified a positive association between mercury exposure and obesity. These findings suggest that toxic environmental metals such as mercury may be an important risk factor for obesity along with dietary habits and lifestyles.

Keywords

Acknowledgement

The authors thank Jihyun Im, Unhui Jo, Chaehyun Kim, Hyeonji Yoo, and Yeeun Park for their technical contributions to this work.

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