Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Canine Lymphoma as a Possible Human Lymphoma Model: A Case-Series Study

  • Kiavash Hushmandi (Division of Epidemiology & Zoonoses, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran ) ;
  • Saied Bokaie (Division of Epidemiology & Zoonoses, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran ) ;
  • Darioush Shirani (Department of Small Animals Internal Medicine, Faculty of Veterinary Medicine, University of Tehran) ;
  • Ali Taghipour (Department of Veterinary Clinical Sciences, Karaj Branch, Islamic Azad University)
  • Received : 2023.04.22
  • Accepted : 2023.05.30
  • Published : 2023.06.30
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Abstract

Canine lymphoma (cL) is the most common hematopoietic cancer in dogs. Various determinants have been evaluated to find the predisposing factors in both human and canine lymphoma. Due to common risk factors and similar pathways, cL is considered a potential model for non-Hodgkin lymphoma (NHL) in humans. In this case-series study, major hospitals in Tehran consented to take part in this study and between the years of 2020-2022, provided us with 52 cL cases which were approved by the attended pathologist. We designed a questionnaire and collected information about the dogs and their owners. Most of the owners were women, young (younger than 50 years old), had at least diplomas and interestingly were housewives or househusbands. Male dogs with middle to old age (more than 6 years) were mostly referred. The most common characteristics were neutered, normal BCS, purebred, urban but not industrial residence, previous tobacco smoke exposure but no history of previous fungicide or pesticide exposure. Also, most of them did not have any previous autoimmune or immunosuppressive diseases. Presented characteristics should be considered risk determinants but to approve their validity, they should be further evaluated in epidemiological studies.

Keywords

Acknowledgement

We would like to thank all individuals who helped us in the process of producing this paper.

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