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Chuna Manual Therapy for Constipation Predominant Irritable Bowel Syndrome: Systematic Review and Meta-analysis

변비형 과민대장증후군에 대한 추나요법의 효과: 체계적 문헌 고찰과 메타분석

  • Sang-Hyun Lee (Department of Korean Medicine, Pusan National University Graduate School) ;
  • Young-Jae Shin (Department of Korean Medicine Rehabilitation, Pusan National University Korean Medicine Hospital) ;
  • Hye-Jin Park (Department of Korean Medicine, Pusan National University Graduate School) ;
  • Eui-Hyoung Hwang (Department of Korean Medicine Rehabilitation, Pusan National University Korean Medicine Hospital)
  • 이상현 (부산대학교 대학원 한의학과) ;
  • 신영재 (부산대학교 한방병원 한방재활의학과) ;
  • 박혜진 (부산대학교 대학원 한의학과) ;
  • 황의형 (부산대학교 한방병원 한방재활의학과)
  • Received : 2023.05.20
  • Accepted : 2023.06.08
  • Published : 2023.06.30

Abstract

Objectives This review aimed to evaluate the effect and clinical utilization of chuna manual therapy (CMT) for constipation predominant irritable bowel syndrome. Methods Literature search was conducted using 12 electronic databases: PubMed, EMBASE, The Cochrane Library, Ovid, Web of Science, Chinese Academic Journals, KMBASE, ScienceOn, Korea Med, OASIS, KISS, and RISS. Only randomized controlled trials (RCTs) using CMT for constipation predominant irritable bowel syndrome treatment were included. The risk of bias of each RCT was evaluated using the Cochrane risk of bias tool. Results Seven RCTs met the inclusion criteria. CMT alone and CMT combined with Western medication showed positive result on constipation predominant irritable bowel syndrome treatment. Two RCTs that compared CMT alone with placebo medicine showed partially positive results in meta-analysis. However, vasoactive intestinal peptide and cholecystokinin values of these studies were evaluated in an opposite way; thus, meta-analysis of these values were not conducted. Conclusions CMT may be effective and clinically utilizable for constipation predominant irritable bowel syndrome treatment. However, there is limited evidence due to lack of well-designed RCTs. Further well-designed RCTs are needed for stronger evidence.

Keywords

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