Acknowledgement
This research was supported by National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (NRF-2021R1F1A1057192) and Korea Environment Industry & Technology Institute (KEITI) through Core Technology Development Project for Environmental Diseases Prevention and Management, funded by Korea Ministry of Environment (MOE) (2021003310002).
References
- Evans, M.J. and Kaufman, M.H. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156. https://doi.org/10.1038/292154a0
- Guan, J., Wang, G., Wang, J., Zhang, Z., Fu, Y., Cheng, L., Meng, G., Lyu, Y., Zhu, J., Li, Y., et al. (2022). Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature 605, 325-331. https://doi.org/10.1038/s41586-022-04593-5
- Hogan, B.L., Cooper, A.R., and Kurkinen, M. (1980). Incorporation into Reichert's membrane of laminin-like extracellular proteins synthesized by parietal endoderm cells of the mouse embryo. Dev. Biol. 80, 289-300. https://doi.org/10.1016/0012-1606(80)90405-4
- Hou, P., Li, Y., Zhang, X., Liu, C., Guan, J., Li, H., Zhao, T., Ye, J., Yang, W., Liu, K., et al. (2013). Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 341, 651-654. https://doi.org/10.1126/science.1239278
- Jia, F., Wilson, K.D., Sun, N., Gupta, D.M., Huang, M., Li, Z., Panetta, N.J., Chen, Z.Y., Robbins, R.C., Kay, M.A., et al. (2010). A nonviral minicircle vector for deriving human iPS cells. Nat. Methods 7, 197-199. https://doi.org/10.1038/nmeth.1426
- Kim, D., Kim, C.H., Moon, J.I., Chung, Y.G., Chang, M.Y., Han, B.S., Ko, S., Yang, E., Cha, K.Y., Lanza, R., et al. (2009). Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476. https://doi.org/10.1016/j.stem.2009.05.005
- Lee, S.W., Wu, G., Choi, N.Y., Lee, H.J., Bang, J.S., Lee, Y., Lee, M., Ko, K., Scholer, H.R., and Ko, K. (2018). Self-reprogramming of spermatogonial stem cells into pluripotent stem cells without microenvironment of feeder cells. Mol. Cells 41, 631-638.
- Long, Y., Wang, M., Gu, H., and Xie, X. (2015). Bromodeoxyuridine promotes full-chemical induction of mouse pluripotent stem cells. Cell Res. 25, 1171-1174. https://doi.org/10.1038/cr.2015.96
- Longo, L., Bygrave, A., Grosveld, F.G., and Pandolfi, P.P. (1997). The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimaerism. Transgenic Res. 6, 321-328. https://doi.org/10.1023/A:1018418914106
- Martin, G.R. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. U. S. A. 78, 7634-7638. https://doi.org/10.1073/pnas.78.12.7634
- Okita, K., Ichisaka, T., and Yamanaka, S. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317. https://doi.org/10.1038/nature05934
- Okita, K., Matsumura, Y., Sato, Y., Okada, A., Morizane, A., Okamoto, S., Hong, H., Nakagawa, M., Tanabe, K., Tezuka, K., et al. (2011). A more efficient method to generate integration-free human iPS cells. Nat. Methods 8, 409-412. https://doi.org/10.1038/nmeth.1591
- Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676. https://doi.org/10.1016/j.cell.2006.07.024
- Takeda, Y., Harada, Y., Yoshikawa, T., and Dai, P. (2018). Chemical compound-based direct reprogramming for future clinical applications. Biosci. Rep. 38, BSR20171650.
- Woltjen, K., Michael, I.P., Mohseni, P., Desai, R., Mileikovsky, M., Hamalainen, R., Cowling, R., Wang, W., Liu, P., Gertsenstein, M., et al. (2009). piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770. https://doi.org/10.1038/nature07863
- Yang, Z., Xu, X., Gu, C., Li, J., Wu, Q., Ye, C., Nielsen, A.V., Mao, L., Ye, J., Bai, K., et al. (2020). Chemicals orchestrate reprogramming with hierarchical activation of master transcription factors primed by endogenous Sox17 activation. Commun. Biol. 3, 629.
- Ye, J., Ge, J., Zhang, X., Cheng, L., Zhang, Z., He, S., Wang, Y., Lin, H., Yang, W., Liu, J., et al. (2016). Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds. Cell Res. 26, 34-45. https://doi.org/10.1038/cr.2015.142
- Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, I.I., and Thomson, J.A. (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801. https://doi.org/10.1126/science.1172482
- Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920. https://doi.org/10.1126/science.1151526
- Zhao, T., Fu, Y., Zhu, J., Liu, Y., Zhang, Q., Yi, Z., Chen, S., Jiao, Z., Xu, X., Xu, J., et al. (2018). Single-cell RNA-seq reveals dynamic early embryonic-like programs during chemical reprogramming. Cell Stem Cell 23, 31-45.e7. https://doi.org/10.1016/j.stem.2018.05.025
- Zhao, Y., Zhao, T., Guan, J., Zhang, X., Fu, Y., Ye, J., Zhu, J., Meng, G., Ge, J., Yang, S., et al. (2015). A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming. Cell 163, 1678-1691. https://doi.org/10.1016/j.cell.2015.11.017