Journal of Korean Neurosurgical Society

  • 제66권4호
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  • Pages.456-464
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  • 2023
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  • 2005-3711(pISSN)
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  • 1598-7876(eISSN)
대한신경외과학회 (The Korean Neurosurgical Society)
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Incidence and Risk Factors of Vestibular Schwannoma in Korea : A Population-Based Study

  • Subin Kim (Department of Otorhinolaryngology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Yun-Hee Lee (Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Sumin, Park (Department of Otorhinolaryngology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Junhui Jeong (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Ki-Hong Chang (Department of Otorhinolaryngology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
  • 투고 : 2022.09.08
  • 심사 : 2022.11.08
  • 발행 : 2023.07.01
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초록

Objective : This study aims to investigate the incidence of vestibular schwannoma (VS) and demographic characteristics in Korea using population-based National Health Insurance Service data. Methods : This study analyzed Korean National Health Insurance Service data from 2005 to 2020, based on the International Classification of Diseases, 10th version, Clinical Modification codes D333 and D431. Only those patients who had undergone magnetic resonance imaging and audiologic tests were considered definitive cases. Demographic variables included age, sex, treatment modality, hypertension, diabetics, dyslipidemia, smoking history, alcohol history, and income status. Results : The total number of VS patients was 5751. The average incidence rate was 0.71 per 100000 from 2005 to 2020, and the annual incidence rate increased from 0.33 in 2005 to 1.32 in 2019 but decreased to 0.80 in 2020. Incidence was highest in those aged 60-69 years (1.791) and lowest in those younger than 20 years (0.041). Incidence was higher in females, and the number of patients who received radiosurgery (46.64%) was largest compared to the wait and scan group (37.96%), microsurgery group (12.85%), or the group who received both (2.56%). Diabetes, dyslipidemia, and alcohol consumption increased the risk of VS, while cigarette smoking reduced the risk of VS. Conclusion : The incidence of VS exhibited an increasing trend from 2005 to 2019. Radiosurgery (46.64%) was the most common treatment modality. Diabetes, dyslipidemia, and alcohol consumption increased the risk of VS, while cigarette smoking reduced the risk of VS.

키워드

과제정보

This study was supported by the Research Fund of the E.N.T. Catholic University of Korea that was created in the program year of 2020.

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