Clinical Endoscopy

  • 제56권6호
  • /
  • Pages.744-753
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  • 2023
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
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Prevalence, natural progression, and clinical practices of upper gastrointestinal subepithelial lesions in Korea: a multicenter study

  • Younghee Choe (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Yu Kyung Cho (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Gwang Ha Kim (Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital) ;
  • Jun-Ho Choi (Department of Internal Medicine, Dankook University College of Medicine) ;
  • Eun Soo Kim (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Ji Hyun Kim (Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine) ;
  • Eun Kwang Choi (Department of Internal Medicine, Jeju National University College of Medicine) ;
  • Tae Hyeon Kim (Department of Internal Medicine, Wonkwang University College of Medicine) ;
  • Seong-Hun Kim (Department of Internal Medicine, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital) ;
  • Do Hoon Kim (Department of Internal Medicine, University of Ulsan college of medicine, Asan Medical Center)
  • 투고 : 2022.11.29
  • 심사 : 2023.04.18
  • 발행 : 2023.11.30
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초록

Background/Aims: This study aimed to evaluate the prevalence and natural progression of subepithelial lesions (SELs) in the upper gastrointestinal (UGI) tract. Methods: The medical records of patients with UGI SELs who underwent endoscopic screening at eight university hospitals between January and December 2010 were retrospectively investigated. The follow-up evaluations were performed until December 2016. Results: UGI SELs were found in 1,044 of the 65,233 participants screened (endoscopic prevalence, 1.60%; the total number of lesions, 1,062; mean age, 55.1±11.2 years; men, 53.6%). The median follow-up period was 48 (range, 8-74) months. SELs were most frequently found in the stomach (63.8%) and had a mean size of 9.9±6.1 mm. Endoscopic ultrasonography (EUS) was performed in 293 patients (28.1%). The most common lesions were leiomyomas, followed by gastrointestinal stromal tumors (GISTs), and ectopic pancreas. The proportions of SELs with malignant potential according to size were 3% (<1 cm), 22% (1-2 cm), 27% (2-3 cm), and 38% (≥3 cm). In gastric SELs larger than 1 cm, resections were performed in 20 patients because of an increase in size, of which 12 were found to be GISTs. Conclusions: The prevalence of UGI SELs was 1.60%. Further, 23% of gastric SELs ≥1 cm were precancerous lesions, most followed by EUS and clinical decisions without initial pathological confirmation.

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참고문헌

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