Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Ischemic colitis complicated by Clostridioides difficile infection treated with fecal microbiota transplantation

  • Seok Hyung Kang (Division of Gastroenterology, International St. Mary's Hospital, Catholic Kwandong University, College of Medicine) ;
  • Tae-Geun Gweon (Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Hyunjung Hwang (Division of Gastroenterology, International St. Mary's Hospital, Catholic Kwandong University, College of Medicine) ;
  • Myong Ki Baeg (Division of Gastroenterology, International St. Mary's Hospital, Catholic Kwandong University, College of Medicine)
  • Received : 2021.07.05
  • Accepted : 2021.08.28
  • Published : 2023.09.30
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Abstract

Ischemic colitis is an inflammatory condition of the colon that results from insufficient blood supply commonly caused by enterocolitis, vessel occlusion, or shock. In contrast, pseudomembranous colitis is a clinical manifestation of Clostridioides difficile infection (CDI). Ischemic colitis caused by CDI has rarely been reported. Fecal microbiota transplantation (FMT) is an efficient treatment for refractory or fulminant CDI, and the indications for its use have recently expanded. However, performing FMT in patients with ischemic colitis is challenging because of the risk of perforation. Here, we have presented a case of ischemic colitis caused by CDI that was successfully treated with FMT via sigmoidoscopy.

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Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (grant number: NRF-2021R1G1A1094049).

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