Clinical Endoscopy

  • 제56권5호
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  • Pages.563-577
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  • 2023
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
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Current status of image-enhanced endoscopy in inflammatory bowel disease

  • Young Joo Yang (Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine)
  • 투고 : 2023.03.05
  • 심사 : 2023.06.22
  • 발행 : 2023.09.30
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초록

In inflammatory bowel disease (IBD), chronic inflammation leads to unfavorable clinical outcomes and increases the risk of developing colorectal neoplasm (CRN); thereby highlighting the importance of endoscopically evaluating disease activity as well as detecting and characterizing CRN in patients with IBD. With recent advances in image-enhanced endoscopic (IEE) technologies, especially virtual chromoendoscopy (VCE) platforms, this review discusses state-of-the-art IEE techniques and their applicability in assessing disease activity and surveillance colonoscopy in patients with IBD. Among various IEE, VCE demonstrated the capacity to identify quiescent disease activity. And endoscopic remission defined by the new scoring system using VCE platform better predicted clinical outcomes, which may benefit the tailoring of therapeutic strategies in patients with IBD. High-definition dye-chromoendoscopy (HD-DCE) is numerically superior to high-definition white light endoscopy (HD-WLE) in detecting CRN in IBD; however, discrepancy is observed in the statistical significance. VCE showed comparable performance in detecting dysplasia to HD-WLE or DCE and potential for optical diagnosis to differentiate neoplastic from nonneoplastic lesions during surveillance colonoscopy. Applying these novel advanced IEE technologies would provide opportunities for personalized medicine in IBD and optimal treatment of CRN in patients with IBD.

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참고문헌

  1. Neurath MF, Travis SP. Mucosal healing in inflammatory bowel diseases: a systematic review. Gut 2012;61:1619-1635.  https://doi.org/10.1136/gutjnl-2012-302830
  2. Ungaro RC, Yzet C, Bossuyt P, et al. Deep remission at 1 year prevents progression of early Crohn's disease. Gastroenterology 2020;159:139-147.  https://doi.org/10.1053/j.gastro.2020.03.039
  3. Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001;48:526-535.  https://doi.org/10.1136/gut.48.4.526
  4. Freeman HJ. Colorectal cancer risk in Crohn's disease. World J Gastroenterol 2008;14:1810-1811.  https://doi.org/10.3748/wjg.14.1810
  5. Kiesslich R, Neurath MF. Chromoendoscopy in inflammatory bowel disease. Gastroenterol Clin North Am 2012;41:291-302.  https://doi.org/10.1016/j.gtc.2012.01.016
  6. Kiesslich R, Neurath MF. Chromoendoscopy: an evolving standard in surveillance for ulcerative colitis. Inflamm Bowel Dis 2004;10:695-696.  https://doi.org/10.1097/00054725-200409000-00031
  7. Rutter M, Bernstein C, Matsumoto T, et al. Endoscopic appearance of dysplasia in ulcerative colitis and the role of staining. Endoscopy 2004;36:1109-1114.  https://doi.org/10.1055/s-2004-826049
  8. Deepak P, Fowler KJ, Fletcher JG, et al. Novel imaging approaches in inflammatory bowel diseases. Inflamm Bowel Dis 2019;25:248-260.  https://doi.org/10.1093/ibd/izy239
  9. Nardone OM, Cannatelli R, Ghosh S, et al. New endoscopic tools in inflammatory bowel disease. United European Gastroenterol J 2022;10:1103-1112.  https://doi.org/10.1002/ueg2.12316
  10. Iacucci M, Furfaro F, Matsumoto T, et al. Advanced endoscopic techniques in the assessment of inflammatory bowel disease: new technology, new era. Gut 2019;68:562-572.  https://doi.org/10.1136/gutjnl-2017-315235
  11. Kodashima S, Fujishiro M. Novel image-enhanced endoscopy with i-scan technology. World J Gastroenterol 2010;16:1043-1049.  https://doi.org/10.3748/wjg.v16.i9.1043
  12. Morimoto Y, Kubo M, Kuramoto M, et al. Development of a new generation endoscope system with lasers "LASEREO". Fujifilm Res Dev 2013;58:1-6. 
  13. Bessissow T, Lemmens B, Ferrante M, et al. Prognostic value of serologic and histologic markers on clinical relapse in ulcerative colitis patients with mucosal healing. Am J Gastroenterol 2012;107:1684-1692.  https://doi.org/10.1038/ajg.2012.301
  14. Park S, Abdi T, Gentry M, et al. Histological disease activity as a predictor of clinical relapse among patients with ulcerative colitis: systematic review and meta-analysis. Am J Gastroenterol 2016;111:1692-1701.  https://doi.org/10.1038/ajg.2016.418
  15. Kudo T, Matsumoto T, Esaki M, et al. Mucosal vascular pattern in ulcerative colitis: observations using narrow band imaging colonoscopy with special reference to histologic inflammation. Int J Colorectal Dis 2009;24:495-501.  https://doi.org/10.1007/s00384-008-0631-9
  16. Sasanuma S, Ohtsuka K, Kudo SE, et al. Narrow band imaging efficiency in evaluation of mucosal healing/relapse of ulcerative colitis. Endosc Int Open 2018;6:E518-E523.  https://doi.org/10.1055/s-0044-102297
  17. Neumann H, Vieth M, Gunther C, et al. Virtual chromoendoscopy for prediction of severity and disease extent in patients with inflammatory bowel disease: a randomized controlled study. Inflamm Bowel Dis 2013;19:1935-1942.  https://doi.org/10.1097/MIB.0b013e318290550e
  18. Iacucci M, Fort Gasia M, Hassan C, et al. Complete mucosal healing defined by endoscopic Mayo subscore still demonstrates abnormalities by novel high definition colonoscopy and refined histological gradings. Endoscopy 2015;47:726-734.  https://doi.org/10.1055/s-0034-1391863
  19. Iacucci M, Kiesslich R, Gui X, et al. Beyond white light: optical enhancement in conjunction with magnification colonoscopy for the assessment of mucosal healing in ulcerative colitis. Endoscopy 2017;49:553-559.  https://doi.org/10.1055/s-0042-124363
  20. Iacucci M, Daperno M, Lazarev M, et al. Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis. Gastrointest Endosc 2017;86:1118-1127.  https://doi.org/10.1016/j.gie.2017.03.012
  21. Trivedi PJ, Kiesslich R, Hodson J, et al. The Paddington International Virtual Chromoendoscopy Score in ulcerative colitis exhibits very good inter-rater agreement after computerized module training: a multicenter study across academic and community practice (with video). Gastrointest Endosc 2018;88:95-106.  https://doi.org/10.1016/j.gie.2018.02.044
  22. Iacucci M, Smith SCL, Bazarova A, et al. An international multicenter real-life prospective study of electronic chromoendoscopy score PICaSSO in ulcerative colitis. Gastroenterology 2021;160:1558-1569.  https://doi.org/10.1053/j.gastro.2020.12.024
  23. Nardone OM, Bazarova A, Bhandari P, et al. PICaSSO virtual electronic chromendoscopy accurately reflects combined endoscopic and histological assessment for prediction of clinical outcomes in ulcerative colitis. United European Gastroenterol J 2022;10:147-159.  https://doi.org/10.1002/ueg2.12185
  24. Cannatelli R, Bazarova A, Furfaro F, et al. Reproducibility of the electronic chromoendoscopy PICaSSO score (Paddington International Virtual ChromoendoScopy ScOre) in ulcerative colitis using multiple endoscopic platforms: a prospective multicenter international study (with video). Gastrointest Endosc 2022;96:73-83.  https://doi.org/10.1016/j.gie.2022.02.012
  25. Iacucci M, Cannatelli R, Parigi TL, et al. A virtual chromoendoscopy artificial intelligence system to detect endoscopic and histologic activity/remission and predict clinical outcomes in ulcerative colitis. Endoscopy 2023;55:332-341.  https://doi.org/10.1055/a-1960-3645
  26. Uchiyama K, Takagi T, Kashiwagi S, et al. Assessment of endoscopic mucosal healing of ulcerative colitis using linked colour imaging, a novel endoscopic enhancement system. J Crohns Colitis 2017;11:963-969.  https://doi.org/10.1093/ecco-jcc/jjx026
  27. Matsumoto K, Oka S, Tanaka S, et al. Clinical usefulness of linked color imaging for evaluation of endoscopic activity and prediction of relapse in ulcerative colitis. Int J Colorectal Dis 2021;36:1053-1061.  https://doi.org/10.1007/s00384-020-03810-9
  28. Nardone OM, Snir Y, Hodson J, et al. Advanced technology for assessment of endoscopic and histological activity in ulcerative colitis: a systematic review and meta-analysis. Therap Adv Gastroenterol 2022;15:17562848221092594. 
  29. Laine L, Kaltenbach T, Barkun A, et al. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. Gastroenterology 2015;148:639-651.  https://doi.org/10.1053/j.gastro.2015.01.031
  30. Alexandersson B, Hamad Y, Andreasson A, et al. High-definition chromoendoscopy superior to high-definition white-light endoscopy in surveillance of inflammatory bowel diseases in a randomized trial. Clin Gastroenterol Hepatol 2020;18:2101-2107.  https://doi.org/10.1016/j.cgh.2020.04.049
  31. Wan J, Zhang Q, Liang SH, et al. Chromoendoscopy with targeted biopsies is superior to white-light endoscopy for the long-term follow-up detection of dysplasia in ulcerative colitis patients: a multicenter randomized-controlled trial. Gastroenterol Rep (Oxf) 2020;9:14-21.  https://doi.org/10.1093/gastro/goaa028
  32. Yang DH, Park SJ, Kim HS, et al. High-definition chromoendoscopy versus high-definition white light colonoscopy for neoplasia surveillance in ulcerative colitis: a randomized controlled trial. Am J Gastroenterol 2019;114:1642-1648.  https://doi.org/10.14309/ajg.0000000000000341
  33. Feuerstein JD, Rakowsky S, Sattler L, et al. Meta-analysis of dye-based chromoendoscopy compared with standard- and high-definition white-light endoscopy in patients with inflammatory bowel disease at increased risk of colon cancer. Gastrointest Endosc 2019;90:186-195.  https://doi.org/10.1016/j.gie.2019.04.219
  34. Gondal B, Haider H, Komaki Y, et al. Efficacy of various endoscopic modalities in detecting dysplasia in ulcerative colitis: a systematic review and network meta-analysis. World J Gastrointest Endosc 2020;12:159-171.  https://doi.org/10.4253/wjge.v12.i5.159
  35. Dekker E, van den Broek FJ, Reitsma JB, et al. Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis. Endoscopy 2007;39:216-221.  https://doi.org/10.1055/s-2007-966214
  36. van den Broek FJ, Fockens P, van Eeden S, et al. Narrow-band imaging versus high-definition endoscopy for the diagnosis of neoplasia in ulcerative colitis. Endoscopy 2011;43:108-115.  https://doi.org/10.1055/s-0030-1255956
  37. Pellise M, Lopez-Ceron M, Rodriguez de Miguel C, et al. Narrow-band imaging as an alternative to chromoendoscopy for the detection of dysplasia in long-standing inflammatory bowel disease: a prospective, randomized, crossover study. Gastrointest Endosc 2011;74:840-848.  https://doi.org/10.1016/j.gie.2011.05.013
  38. Bisschops R, Bessissow T, Joseph JA, et al. Chromoendoscopy versus narrow band imaging in UC: a prospective randomised controlled trial. Gut 2018;67:1087-1094.  https://doi.org/10.1136/gutjnl-2016-313213
  39. Iacucci M, Kaplan GG, Panaccione R, et al. A randomized trial comparing high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy for detection of colonic neoplastic lesions during IBD surveillance colonoscopy. Am J Gastroenterol 2018;113:225-234.  https://doi.org/10.1038/ajg.2017.417
  40. Kandiah K, Subramaniam S, Thayalasekaran S, et al. Multicentre randomized controlled trial on virtual chromoendoscopy in the detection of neoplasia during colitis surveillance high-definition colonoscopy (the VIRTUOSO trial). Gut 2021;70:1684-1690.  https://doi.org/10.1136/gutjnl-2020-320980
  41. El-Dallal M, Chen Y, Lin Q, et al. Meta-analysis of virtual-based chromoendoscopy compared with dye-spraying chromoendoscopy standard and high-definition white light endoscopy in patients with inflammatory bowel disease at increased risk of colon cancer. Inflamm Bowel Dis 2020;26:1319-1329.  https://doi.org/10.1093/ibd/izaa011
  42. Resende RH, Ribeiro IB, de Moura DT, et al. Surveillance in inflammatory bowel disease: is chromoendoscopy the only way to go?: a systematic review and meta-analysis of randomized clinical trials. Endosc Int Open 2020;8:E578-E590.  https://doi.org/10.1055/a-1120-8376
  43. Neumann H, Neurath MF, Mudter J. New endoscopic approaches in IBD. World J Gastroenterol 2011;17:63-68.  https://doi.org/10.3748/wjg.v17.i1.63
  44. Rabinowitz LG, Kumta NA, Marion JF. Beyond the SCENIC route: updates in chromoendoscopy and dysplasia screening in patients with inflammatory bowel disease. Gastrointest Endosc 2022;95:30-37.  https://doi.org/10.1016/j.gie.2021.07.024
  45. Bisschops R, East JE, Hassan C, et al. Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline: update 2019. Endoscopy 2019;51:1155-1179.  https://doi.org/10.1055/a-1031-7657
  46. Murthy SK, Feuerstein JD, Nguyen GC, et al. AGA clinical practice update on endoscopic surveillance and management of colorectal dysplasia in inflammatory bowel diseases: expert review. Gastroenterology 2021;161:1043-1051.  https://doi.org/10.1053/j.gastro.2021.05.063
  47. Carballal S, Maisterra S, Lopez-Serrano A, et al. Real-life chromoendoscopy for neoplasia detection and characterisation in long-standing IBD. Gut 2018;67:70-78.  https://doi.org/10.1136/gutjnl-2016-312332
  48. Sugimoto S, Naganuma M, Iwao Y, et al. Endoscopic morphologic features of ulcerative colitis-associated dysplasia classified according to the SCENIC consensus statement. Gastrointest Endosc 2017;85:639-646.  https://doi.org/10.1016/j.gie.2016.11.013
  49. Aladren BS, Gonzalez-Lama Y, Garcia-Alvarado M, et al. Even non-experts identify non-dysplastic lesions in inflammatory bowel disease via chromoendoscopy: results of a screening program in real-life. Endosc Int Open 2019;7:E743-E750.  https://doi.org/10.1055/a-0839-4514
  50. Matsumoto T, Kudo T, Jo Y, et al. Magnifying colonoscopy with narrow band imaging system for the diagnosis of dysplasia in ulcerative colitis: a pilot study. Gastrointest Endosc 2007;66:957-965.  https://doi.org/10.1016/j.gie.2007.04.014
  51. Bisschops R, Bessissow T, Dekker E, et al. Pit pattern analysis with high-definition chromoendoscopy and narrow-band imaging for optical diagnosis of dysplasia in patients with ulcerative colitis. Gastrointest Endosc 2017;86:1100-1106.  https://doi.org/10.1016/j.gie.2017.09.024
  52. Iacucci M, McQuaid K, Gui XS, et al. A multimodal (FACILE) classification for optical diagnosis of inflammatory bowel disease associated neoplasia. Endoscopy 2019;51:133-141.  https://doi.org/10.1055/a-0757-7759
  53. Cassinotti A, Buffoli F, Fociani P, et al. Virtual chromoendoscopy with FICE for the classification of polypoid and nonpolypoid raised lesions in ulcerative colitis. J Clin Gastroenterol 2019;53:269-276.  https://doi.org/10.1097/MCG.0000000000000974
  54. Cassinotti A, Fociani P, Duca P, et al. Modified Kudo classification can improve accuracy of virtual chromoendoscopy with FICE in endoscopic surveillance of ulcerative colitis. Endosc Int Open 2020;8:E1414-E1422. https://doi.org/10.1055/a-1165-0169