Annals of Occupational and Environmental Medicine

  • Volume 35
  • /
  • Pages.52.1-52.13
  • /
  • 2023
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  • 1225-3618(pISSN)
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  • 2052-4374(eISSN)
The Korean Society of Occupational & Environmental Medicine (대한직업환경의학회)
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Prostate cancer in workers exposed to night-shift work: two cases recognized by the Korean Epidemiologic Investigation Evaluation Committee

  • Sungkyun Park (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency) ;
  • Seongwon Ma (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency) ;
  • Hoekyeong Seo (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency) ;
  • Sang Gil Lee (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency) ;
  • Jihye Lee (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency) ;
  • Shinhee Ye (Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency)
  • Received : 2023.05.08
  • Accepted : 2023.11.07
  • Published : 2023.12.31
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Abstract

Background: In 2019, the International Agency for Research on Cancer re-evaluated the carcinogenicity of night-shift work and reported that there is limited evidence that night-shift work is carcinogenic for the development of prostate cancer. Therefore, in 2020 and 2021, the Korean Epidemiologic Investigation Evaluation Committee concluded that 2 cases of prostate cancer were occupational diseases related to the night-shift work. Here, we report the 2 cases of prostate cancer in night-shift workers which were first concluded as occupational diseases by the Korean Epidemiologic Investigation Evaluation Committee. Case presentation: Patient A: A 61-year-old man worked as a city bus driver for approximately 17 years, from 2002 to 2019, and was exposed to night-shift work during this period. In March 2017, the patient was diagnosed with high-grade prostate cancer through core-needle biopsy after experiencing stinging pain lasting for 2 months. Patient B: A 56-year-old man worked as an electrician and an automated equipment operator in a cement manufacturing plant for 35 years from 1976 to 2013 and was exposed to night-shift work during this period. In 2013, the patient was diagnosed with high-grade prostate cancer through core needle biopsy at a university hospital because of dysuria that lasted for 6 months. Conclusions: The 2 workers were diagnosed with high-grade prostate cancer after working night shifts for 17 and 35 years respectively. Additionally, previous studies have reported that high-grade prostate cancer has a stronger relationship with night-shift work than low or medium-grade prostate cancer. Therefore, the Korean Epidemiologic Investigation Evaluation Committee concluded that night-shift work in these 2 patients contributed to the development of their prostate cancer.

Keywords

Acknowledgement

The present study utilized workers' data that were formally obtained from the Occupational Safety and Health Research Institute (OSHRI), and the Korean Occupational Safety and Health Agency (KOSHA) and did not include identifiable personal information.

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