Journal of Cardiovascular Imaging

  • 제31권1호
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  • Pages.41-48
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  • 2023
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  • 2586-7210(pISSN)
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  • 2586-7296(eISSN)
한국심초음파학회 (Korean Society of Echocardiography)
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Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy

  • Se-Jung Yoon (Division of Cardiology, National Health Insurance Service Ilsan Hospital) ;
  • Sungha Park (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Eui-Young Choi (Division of Cardiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Hye-Sun Seo (Division of Cardiology, Soonchunhyang University Bucheon Hospital) ;
  • Chi Young Shim (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Chul Min Ahn (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Sung-Ai Kim (Division of Cardiology, Hallym University Medical Center) ;
  • Jong-Won Ha (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine)
  • 투고 : 2022.05.22
  • 심사 : 2022.09.05
  • 발행 : 2023.01.27
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초록

BACKGROUND: The function of left atrium (LA) is difficult to assess because of its ventricle-dependent, dynamic movement. The aim of this study was to assess LA function using velocity vector imaging (VVI) and compare LA function in patients with hypertrophic cardiomyopathy (HCMP) and left ventricular hypertrophy (LVH) with normal controls. METHODS: Fourteen patients with HCMP (72% male, mean age of 52.6 ± 9.8), 15 hypertensive patients with LVH (88% male, mean age of 54.0 ± 15.3), and 10 age-matched controls (83% male, mean age of 50.0 ± 4.6) were prospectively studied. Echocardiographic images of the LA were analyzed with VVI, and strain rate (SR) was compared among the 3 groups. RESULTS: The e' velocity (7.7 ± 1.1; 5.1 ± 0.8; 4.5 ± 1.3 cm/sec, p = 0.013), E/e' (6.8 ± 1.6; 12.4 ± 3.3; 14.7 ± 4.2, p = 0.035), and late diastolic SR at mid LA (-1.65 ± 0.51; -0.97 ± 0.55; -0.82 ± 0.32, p = 0.002) were significantly different among the groups (normal; LVH; HCMP, respectively). The e' velocity, E/e', and late diastolic SR at mid LA were significantly different between normal and LVH (p = 0.001; 0.022; 0.018), whereas LA size was similar between normal and LVH (p = 0.592). The mean late diastolic peak SR of mid LA was significantly correlated with indices of diastolic function (E/e', e', and LA size). CONCLUSIONS: The SR is a useful tool for detailed evaluation of LA function, especially early dysfunction of LA in groups with normal LA size.

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참고문헌

  1. Etemad T, Hosseinsabet A, Omidi N, Mohseni-Badalabadi R. Determinants of the volumetric markers of left atrial contraction function in coronary artery disease: a cross-sectional study. J Cardiovasc Imaging 2022;30:37-46.
  2. Akcay M, Coksevim M, Ulubasoglu H, Gedikli O, Yilmaz O. Evaluation of left atrial electromechanical delay and left atrial phasic functions in surgical early menopause patients. J Cardiovasc Imaging 2019;27:137-46.
  3. Grant C, Bunnell IL, Greene DG. The reservoir function of the left atrium during ventricular systole. An angiocardiographic study of atrial stroke volume and work. Am J Med 1964;37:36-43.
  4. Kuo LC, Quinones MA, Rokey R, Sartori M, Abinader EG, Zoghbi WA. Quantification of atrial contribution to left ventricular filling by pulsed Doppler echocardiography and the effect of age in normal and diseased hearts. Am J Cardiol 1987;59:1174-8.
  5. Spencer KT, Mor-Avi V, Gorcsan J 3rd, et al. Effects of aging on left atrial reservoir, conduit, and booster pump function: a multi-institution acoustic quantification study. Heart 2001;85:272-7.
  6. Di Salvo G, Caso P, Lo Piccolo R, et al. Atrial myocardial deformation properties predict maintenance of sinus rhythm after external cardioversion of recent-onset lone atrial fibrillation: a color Doppler myocardial imaging and transthoracic and transesophageal echocardiographic study. Circulation 2005;112:387-95.
  7. Sun BJ, Park JH, Lee M, et al. Normal reference values for left atrial strain and its determinants from a large Korean multicenter registry. J Cardiovasc Imaging 2020;28:186-98.
  8. Pellerin D, Sharma R, Elliott P, Veyrat C. Tissue Doppler, strain, and strain rate echocardiography for the assessment of left and right systolic ventricular function. Heart 2003;89 Suppl 3:iii9-17.
  9. Yang L, Qiu Q, Fang SH. Evaluation of left atrial function in hypertensive patients with and without left ventricular hypertrophy using velocity vector imaging. Int J Cardiovasc Imaging 2014;30:1465-71.
  10. Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 2015;28:1-39.e14.
  11. Gan GC, Bhat A, Chen HH, et al. Left atrial reservoir strain by speckle tracking echocardiography: association with exercise capacity in chronic kidney disease. J Am Heart Assoc 2021;10:e017840.
  12. Zhu M, Chen H, Liu Y, Shu X. Clinical implication of disturbed left atrial phasic functions in the heterogeneous population associated with hypertension or atrial fibrillation. Cardiovasc Ultrasound 2019;17:25.
  13. Lin J, Ma H, Gao L, et al. Left atrial reservoir strain combined with E/E' as a better single measure to predict elevated LV filling pressures in patients with coronary artery disease. Cardiovasc Ultrasound 2020;18:11.
  14. Donal E, Raud-Raynier P, De Place C, et al. Resting echocardiographic assessments of left atrial function and filling pressure interest in the understanding of exercise capacity in patients with chronic congestive heart failure. J Am Soc Echocardiogr 2008;21:703-10.
  15. Sutherland GR, Di Salvo G, Claus P, D'hooge J, Bijnens B. Strain and strain rate imaging: a new clinical approach to quantifying regional myocardial function. J Am Soc Echocardiogr 2004;17:788-802.
  16. Telagh R, Hui W, Abd El Rahman M, Berger F, Lange PE, Abdul-Khaliq H. Assessment of regional atrial function in patients with hypertrophic cardiomyopathies using tissue Doppler imaging. Pediatr Cardiol 2008;29:301-8.
  17. Paraskevaidis IA, Panou F, Papadopoulos C, et al. Evaluation of left atrial longitudinal function in patients with hypertrophic cardiomyopathy: a tissue Doppler imaging and two-dimensional strain study. Heart 2009;95:483-9.
  18. Eshoo S, Semsarian C, Ross DL, Marwick TH, Thomas L. Comparison of left atrial phasic function in hypertrophic cardiomyopathy versus systemic hypertension using strain rate imaging. Am J Cardiol 2011;107:290-6.
  19. Zhang Q, Yip GW, Yu CM. Approaching regional left atrial function by tissue Doppler velocity and strain imaging. Europace 2008;10 Suppl 3:iii62-9.
  20. Quintana M, Lindell P, Saha SK, et al. Assessment of atrial regional and global electromechanical function by tissue velocity echocardiography: a feasibility study on healthy individuals. Cardiovasc Ultrasound 2005;3:4.
  21. Huang J, Yang C, Ni CF, Yan ZN, Fan L, Song XT. Right atrial function assessed by volume-derived values and speckle tracking echocardiography in patients with hypertrophic cardiomyopathy. BMC Cardiovasc Disord 2020;20:335.
  22. Badran HM, Faheem N, Elnoamany MF, Kenawy A, Yacoub M. Characterization of left atrial mechanics in hypertrophic cardiomyopathy and essential hypertension using vector velocity imaging. Echocardiography 2015;32:1527-38.
  23. Badran HM, Soltan G, Hassan H, et al. Changes in left atrial deformation in hypertrophic cardiomyopathy: evaluation by vector velocity imaging. Glob Cardiol Sci Pract 2013;2012:67-80.
  24. Kojima T, Kawasaki M, Tanaka R, et al. Left atrial global and regional function in patients with paroxysmal atrial fibrillation has already been impaired before enlargement of left atrium: velocity vector imaging echocardiography study. Eur Heart J Cardiovasc Imaging 2012;13:227-34.
  25. Pichette M, Serri K, Page M, Di LZ, Bichet DG, Poulin F. Impaired left atrial function in fabry disease: a longitudinal speckle-tracking echocardiography study. J Am Soc Echocardiogr 2017;30:170-179.e2.
  26. Scherr J, Jung P, Schuster T, et al. Left ventricular diastolic function is strongly correlated with active emptying of the left atrium: a novel analysis using three-dimensional echocardiography. Cardiovasc Ultrasound 2016;14:43.
  27. de Gregorio C, Dattilo G, Casale M, Terrizzi A, Donato R, Di Bella G. Left atrial morphology, size and function in patients with transthyretin cardiac amyloidosis and primary hypertrophic cardiomyopathy - comparative strain imaging study. Circ J 2016;80:1830-7.
  28. Zhou D, Yang W, Yang Y, et al. Left atrial dysfunction may precede left atrial enlargement and abnormal left ventricular longitudinal function: a cardiac MR feature tracking study. BMC Cardiovasc Disord 2022;22:99.
  29. Kobayashi Y, Wheeler M, Finocchiaro G, et al. Left atrial function and phenotypes in asymmetric hypertrophic cardiomyopathy. Echocardiography 2017;34:843-50.
  30. Pirat B, McCulloch ML, Zoghbi WA. Evaluation of global and regional right ventricular systolic function in patients with pulmonary hypertension using a novel speckle tracking method. Am J Cardiol 2006;98:699-704.