DOI QR코드

DOI QR Code

Complete Genome of Methicillin-Resistant Staphylococcus epidermidis Z0118SE0272 Isolated from a Residential Environment

  • Haeseong Lee (Division of Biotechnology, Jeonbuk National University) ;
  • Jae-Young Oh (Division of Biotechnology, Jeonbuk National University) ;
  • Kui Jae Lee (Division of Biotechnology, Jeonbuk National University) ;
  • Jong-Chan Chae (Division of Biotechnology, Jeonbuk National University)
  • 투고 : 2023.11.16
  • 심사 : 2023.12.05
  • 발행 : 2023.12.28

초록

Staphylococcus epidermidis is a normal flora of human skin and is occasionally associated with pathogenic infections. We report the complete genome sequence of methicillin-resistant Staphylococcus epidermidis strain Z0118SE0272 isolated from the residential environment sharing by a companion dog and dwellers. Resistance to cefoxitin was observed in the strain, whereas it was susceptible to erythromycin, clindamycin, quinupristin-dalfopristin, trimethoprim-sulfamethoxazole, mupirocin, vancomycin, teicoplanin, linezolid, and tigecycline. The strain Z0118SE0272 identified as sequence type 130 possessed the mecA gene responsible for methicillin resistance, which composed the new type of staphylococcal cassette chromosome mec elements lacking mecRI.

키워드

과제정보

This work was supported by grants of Korea Disease Control and Prevention Agency (2022-ER2103-00), Ministry of Food and Drug Safety (23194MFDS012), and Jeonbuk National University.

참고문헌

  1. Battaglia M, Garrett-Sinha LA. 2023. Staphylococcus xylosus and Staphylococcus aureus as commensals and pathogens on murine skin. Lab. Anim. Res. 39: 18.
  2. Flurin L, Greenwood-Quaintance KE, Patel R. 2019. Microbiology of polymicrobial prosthetic joint infection. Diagn. Microbiol. Infect. Dis. 94: 255-259. https://doi.org/10.1016/j.diagmicrobio.2019.01.006
  3. O'Gara JP, Humphreys H. 2001. Staphylococcus epidermidis biofilms: importance and implications. J. Med. Microbiol. 50: 582-587. https://doi.org/10.1099/0022-1317-50-7-582
  4. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. 2004. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin. Infect. Dis. 39: 309-317. https://doi.org/10.1086/421946
  5. Watanabe K, Nakaminami H, Azuma C, Tanaka I, Nakase K, Matsunaga N, et al. 2016. Methicillin-resistant Staphylococcus epidermidis is part of the skin flora on the hands of both healthy individuals and hospital workers. Biol. Pharm. Bull. 39: 1868-1875. https://doi.org/10.1248/bpb.b16-00528
  6. Uehara Y. 2022. Current status of staphylococcal cassette chromosome mec (SCCmec). Antibiotics 11: 86.
  7. Sharma P, Satorius AE, Raff MR, Rivera A, Newton DW, Younger JG. 2014. Multilocus sequence typing for interpreting blood isolates of Staphylococcus epidermidis. Interdiscip. Perspect. Infect. Dis. 2014: 787458.
  8. Wick RR, Judd LM, Gorrie CL, Holt KE. 2017. Unicycler: resolving bacterial genome assemblies from short and long sequencing reads. PLoS Comput. Biol. 13: e1005595.
  9. Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, et al. 2020. CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database. Nucleic Acids Res. 48: D517-D525. https://doi.org/10.1093/nar/gkz935
  10. Kaya H, Hasman H, Larsen J, Stegger M, Johannesen TB, Allesoe RL, et al. 2018. SCC mec Finder, a web-based tool for typing of staphylococcal cassette chromosome mec in Staphylococcus aureus using whole-genome sequence data. mSphere 3: e00612-17.