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Draft Genome Sequence of the Yeast Strain Hormonema macrosporum POB-4, which Produces the Biosurfactant Glycocholic Acid

  • Parthiban Subramanian (National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Jeong-Seon Kim (Agricultural Microbiology Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Jun Heo (Agricultural Microbiology Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Yiseul Kim (Agricultural Microbiology Division, National Institute of Agricultural Sciences, Rural Development Administration)
  • Received : 2023.10.05
  • Accepted : 2023.11.07
  • Published : 2023.12.28

Abstract

We report the draft genome sequence of the yeast strain Hormonema macrosporum POB-4, capable of producing the biosurfactant glycocholic acid, one of the bile acids. A majority of genes with known function were associated with metabolism and transport of amino acid and carbohydrate as well as secondary metabolites biosynthesis, transport, and catabolism. We observed genes of eleven C-N hydrolases and two CoA transferases which have been reported to be involved in the biosynthesis of glycocholic acid. Further experimental studies can help to elucidate the specific genes responsible for biosurfactant production in strain POB-4.

Keywords

Acknowledgement

This study (Project No. 015675) was carried out with the support of National Institute of Agricultural Sciences, Rural Development Administration, Republic of Korea.

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